Impressive data on novel treatment for SLE were presented at the EULAR22 Congress. A disease that is difficult to study due to its pleomorphic presentation, unpredictable disease course, and high mortality rates, SLE is considered the dragon of all autoimmune diseases. Here are highlights of four exciting abstracts presented at the meeting with emerging therapeutics designed to slay the beast.
All News
Article
Article
Bags are packed, ready to go, but wait there’s more abstracts to show.
The big news today were the “late breaking” abstracts. This is usually a favorite session of many as this is where the newest of study data often is showcased.
Article
Topical treatments have so often been the low level “sure you can try this” option. However there are exciting data that these approaches may become part of our main armamentarium.
Article
By now, those of us attending the meeting know how to find a free coffee or sprite, have found comfortable meeting nooks and know our way around! PAnd congrats to you virtual Rheums for mastering the multi-screen, multitask simultaneous consumption posters, tweets and oral abstract presentations.
Watch: Let’s Talk about Sex and Autoimmune Disease
Dr. Eric Dein discusses abstract OP0139 presented at #EULAR2022.
https://t.co/fNcIbykFqL https://t.co/6UaH5DIc51
Topical therapies take centre stage
Topical treatments have so often been the low level “sure you can try this” option. However there are exciting data that these approaches may become part of our main armamentarium. #EULAR2022
https://t.co/V9plk1vAEd https://t.co/fyNWWtconi
Laurent ARNAUD
Tweet
🆒 Couldn't attend my #EULAR2022 talk about the role of #twitter in #Rheumatology?
Check the 2 slides below summarizing the role of #socialmedia for the dissemination of medical information. #TwitterRheum
⬇️ BEFORE vs AFTER Twitter ⬇️ https://t.co/ZzVdoWYEMr
Watch: #EULAR2022 - Day 4 Faculty Panel Recap
Dr. David Liew and Dr. Jack Cush discuss day 4 of EULAR 2022. LB0001, LB0002, LB0004, and LB0006.
https://t.co/B7AYkTnAe0 https://t.co/NF3f6AFv6K
#EULAR2022 – Day 4 Report
Check out our my favorite late-breakers from Day 4.
https://t.co/R0hPetOos4 https://t.co/T57XRIKZs5
WATCH: #EULAR2022 - Day 3 Faculty Panel Recap
Drs. Jack Cush, Janet Pope, Aurelie Najm and Yuz Yusof discuss highlights from Day 3 of EULAR 2022.
https://t.co/ExCXY6Xbl4
@Janetbirdope @AurelieRheumo @Yuz6Yusof https://t.co/tIB8QrdYuI
David Liew
Tweet
MIVAC I & II RCTs from India:
for AZ vaccine (ChAdOx1), withhold MTX for 2w after:
hold both dose 1&2
or hold just dose 2
(vs continue)
Endpoint: Ab titre
both hold approaches better than continue, to a similar magnitude
- similar to German study w mRNA
#EULAR2022 @RheumNow
#LB0006 #EULAR2022 Therapy for relapsing polymyalgia rheumatica. 118/280 recruited re:COVID impact. Phase 3 RCT of Sarilumab+14Wk Steroid taper showed more pts had sustained remission at Wk52 vs PBO+52Wk Steroid Taper(28% vs 10%) even if CRP excluded. PRO improved too! @RheumNow https://t.co/P11iXIAfGn
Dr. Antoni Chan
Tweet
Novel ePROMS use. Use of ePROMS RAPID3/PASS and asking patients if they had a flare had high diagnostic accuracy identifying those not needing DMARD or steroid intensification up and eligible to skip their next outpatient clinic visit. Seppen et al #EULAR2022 @RheumNow POS0381
Dr. Antoni Chan
Tweet
Who remotely enters PROs online? Glintborg et al from the Danbio Registry showed that patients who used the system were mainly 40-80 years of age, on biologics and had lower HAQ score. Disease duration and diagnosis had no impact, reminders helped #EULAR2022 @RheumNow POS0373 https://t.co/voCfGiJgwm
#POS1112 #EULAR2022 A crossover RCT assessed effect of weight- and non-weight bearing exercises on type 2 collagen in knee #osteoarthritis. Small rise in collagen turnover markers initially for 24hrs. Gradual rise later on was contributed to cardiovascular influence @RheumNow https://t.co/AOxdFNihPR
David Liew
Tweet
The potential for patients to benefit from digital health technologies in rheumatology is multifaceted, upside might be enormous.
There's so much space for us all, but there are factors in many domains where it can all go wrong.
We need to raise standards.
#EULAR2022 @RheumNow https://t.co/TozfK1Qs16
David Liew
Tweet
Agree. Love to understand:
- standardisation for whole body MRI
- how it does not compromise image quality vs limited field
- clear explanation of benefit vs limited field, where it exists
Its inappropriate use in the worried well by charlatans has skewed me #EULAR2022 @RheumNow https://t.co/3LRz0OOAEF
Richard Conway
Tweet
Sousa et al. Anti-Ku disease. Cluster analysis (Ku alone, Ku with other abs) asking is is a distinct entity. In isolated anti-Ku+ maybe so, characterised by Raynauds (41%), arthritis (26%), sicca (26%), myositis (15%), ILD (15%) @RheumNow #EULAR2022 POS0861 https://t.co/IboWzMYFMB
#OP0286 #EULAR2022 With no licensed therapy, we need a better and responsive outcome measure. Using data-driven method, SJÖGREN’S TOOL FOR ASSESSING RESPONSE (STAR) has been developed. This will be evaluated in NECESSITY RCTs across Europe @RheumNow https://t.co/U5Aj6bwWBy
David Liew
Tweet
So maybe, when it comes to delivering healthcare and telemedicine, we need to think about quality and efficiency? #EULAR2022 @RheumNow https://t.co/JMbQ1ZUB0o


