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Lungs ILD

Actemra FDA Approved for Systemic Sclerosis Interstitial Lung Disease

Jack Cush, MD

Genentech announced Thursday that the US Food and Drug Administration approved tocilizumab (Actemra) for the treatment of Systemic Sclerosis-associated Interstitial Lung Disease (SSc-ILD), specifically indicated for slowing the rate of decline in pulmonary function in adul

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RheumNow Podcast – Pounds of Prevention (3.5.2021)

Jack Cush, MD

Dr. Jack Cush reviews and discusses nearly a dozen news reports and journal articles from the past week on RheumNow.com.

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RheumNow Podcast – Sweet Lies or Hard Truths? (2.26.2021)

Jack Cush, MD

Dr. Jack Cush reviews and discusses the news and Journal reports from the past week on RheumNow.com.

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Lung Preservation with Tocilizumab in Early Systemic Sclerosis

Jack Cush, MD

Arthritis & Rheumatology has published the results of a subanalysis from tocilizumab (TCZ) clinical trials showing that Il-6 inhibition was associated with preservation of lung function patients with early systemic sclerosis (SSc).

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RheumNow Podcast – Systemic Sclerosis Pearls (2.19.2021)

Jack Cush, MD

Dr. Jack Cush reviews nearly a dozen news and journal reports from the past 2 weeks on RheumNow.com, including the ACR's new COVID-19 vaccine guidance for patients with rheumatic disease.

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RheumNow Podcast – Rheumatology Burnout (1.29.2021)

Jack Cush, MD

Dr. Jack Cush reviews this past week's journal articles and news features on RheumNow.com. Colchicine, vaccine rollout, risk of RA in endometriosis patients, tREACH trial, lupus nephritis news, rheumatology burnout and more.

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2020 Year Review

2020 Rheumatology Year in Review

Jack Cush, MD

2020 was historic, memorable and game-changing. Under the cloud of COVID-19, there were many significant and memorable advances and setbacks for the rheumatology world. In our accounting of most read articles for 2020, (not surprisingly) 17/20 were COVID-related.

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News Feature: Rituximab in Systemic Sclerosis? A recent metanalysis suggests that rituximab may improve skin score and disease activity indices (DAS, mRSS) while stabilizing organ involvement in SSc patients. https://t.co/lH7aP7ht10 https://t.co/UdV8NRHxdC

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News Feature: Actemra FDA Approved for Systemic Sclerosis Interstitial Lung Disease https://t.co/6A4muejeH9 https://t.co/D3JSfBpRZx

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Dr. John Cush RheumNow ( View Tweet)
News Feature: Actemra FDA Approved for Systemic Sclerosis Interstitial Lung Disease https://t.co/6A4muejeH9 https://t.co/xQbIoEEscv

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QD Clinic: PFAPA Syndrome Recurrent Fevers, Stomatitis, Lymphadenopathy ? https://t.co/uMBk8e2wJO https://t.co/02ZMjRmOuU

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Systemic Sclerosis is 5 times more prevalent in women than men. Analysis of epidemiology studies shows SSc prevalence as 17.6 per 100000 and pooled incidence of SSc was 1.4 per 100000 PYs. https://t.co/RyVIBUWyen

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A woman w/ Raynauds, puffy fingers, nailfold capillary changes, abundant mat telangiectases consistent with limited cutaneous systemic sclerosis. Telangiectasias can be on skin, oral mucosa, GI tract & may associate w/ pulm HTN. https://t.co/FcL4VHMpmM

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New Video: Dry Eyes and Tripping Over Tires RWCS 2021 Poster Session by Dr. Faizan Ahmad https://t.co/9UymYbYcJ0

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RheumNow Podcast is now up! Systemic Sclerosis Pearls Dr. Jack Cush reviews nearly a dozen news and journal reports from the past 2 weeks on https://t.co/fxtCOkxTER, https://t.co/nKRmKWR0Bd https://t.co/ESdycxLoCz

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Study of Systemic Sclerosis patients from the EUSTAR database: shows of the 144 with anti-PM/Scl+ Abs, there was an increased risk of muscle involvement, ILD, calcinosis and dermatomyositis; muscle involvement had a more severe disease phenotype. https://t.co/ORA2y1BWgn

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Dry Eyes and Tripping Over Tires RWCS 2021 Poster Session by Dr. Faizan Ahmad https://t.co/9UymYbYcJ0

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Dr. John Cush RheumNow ( View Tweet)

Systemic Sclerosis Rapid Onset Pulmonary Arterial Hypertension Pulmonary Capillary Hemangiomatosis RWCS 2021 Poster Session by Dr. Jason Melehani, Stanford University https://t.co/wfxiY2VqcN

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Johns Hopkins & UCSF Scleroderma pts tested for Abs against telomerase & shelterin (TERF1); while rare in RA, myositis, controls; TERF1 Abs seen in 9% of SSc & assoc w/ severe lung disease (OR 2.4) & shorter telomere length. (TERF1 found in 7% of IPF) https://t.co/e5ai8uO4kK

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Osteitis in Systemic Sclerosis is UNCOMMON. French study of 48 pts shows 54% w/ osteitis beneath digital tip ulcers. Pain (75%), erythema (73%), warmth (73%) & 65% had high CRP. X‐ray, CT‐scans or MR. Antibiotics were 1st line therapy. https://t.co/o58gwq2SCC

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