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$30 Billion and Counting (4.29.2022)

Apr 29, 2022 1:10 pm

Dr. Jack Cush reviews the news and journal reports and takes viewer questions this week.

  1. Global Rheumatology Therapeutics (drug) Market size is estimated to be $29.37 billion (USD) in 2022, and is projected to grow to $40.13 billion by 2027. .

  2. Pregnancy outcomes in systemic sclerosis (SSc) studied in 154 pregnancies from SSc, SLE, APS, & controls (2008 to 2019). Adverse Preg Outcomes APO significantly higher in SSc vs HC (61% vs 10%) w/ more miscarriages, preeclampsia, SGA & preterm births

  3. Systematic literature review of studies where steroids were used as initial "Bridge Therapy" in RA patients - included 10 studies, but only 4 RCTs w/ protocolized discontinuation - these showed 22% were still on GC @ 12 mos, 10% @24 mos

  4. Cardiovascular risk (CVR) was assessed in Psoriasis (#PSO) & #PSA in multiracial population in S Brazil using the Framingham Risk Score. Compared to controls PSO & PSA had higher FRS (16.3 & 18 vs 10.6) and also increased with age. Hig

  5. FDA approved 1st drug for kids with COVID-19. Veklury (remdesivir) get an expanded indication in Peds >28days old & wt > 3 kg who has SARS-CoV-2 & are Hospitalized, or Not hospitalized & at high risk for severe COVID-19 or death

  6. One centers experience with a combined Rheum-Derm Clinic. Among 151 psoriasis patients with suspicious musculoskeletal complaints, 85% were dx w/ PsA - 62% of these PsA was 1st diagnosed.

  7. Study of PCP Dx irritable bowel dz; 459 randomised to 8 weeks of oral antispasmodics or diet (low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP). Better responses with diet (71% vs 61%; p=0.03). Better adherence w/ diet.

  8. Nature study shows videoconferencing inhibits creativity (idea generation) because it focuses communicators on a screen, which prompts a narrower cognitive focus. Yet, virtual interaction might increase decision quality.

  9. Arthritis Predicts Hepatic Fibrosis in Hemochromatosis 

  10. #ACA – Ask Cush Anything – CRP and Arthralgias?

  11. TNR Tuesday, May 3, 2022  Rheumatoid arthritis discussion with Drs. Cush, Michaud, Choy

The author has received compensation as an advisor or consultant on this subject

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