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FDA Approves Bimekizumab for Plaque Psoriasis
UCB announced today that the US Food and Drug Administration (FDA) has approved bimekizumab-bkzx (Bimzelx)) for the treatment of moderate to severe plaque psoriasis in adults who needing systemic therapy or phototherapy.
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PMR and Palindromic Rheumatism Similarities
I'd like to discuss the similarities between polymyalgia rheumatica and palindromic rheumatism. And in doing that, highlight how these similarities help us understand the relationship between polymyalgia rheumatica and rheumatoid arthritis. Perhaps not everybody watching this will be very familiar with palindromic rheumatism. It is considered uncommon, but every rheumatologist sees it in their practice.
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2023 EULAR Lupus Management Recommendations
EULAR has published updated recommendations for the management of systemic lupus erythematosus (SLE) based on new evidence and expert opinion - formulationg five overarching principles and 13 recommendations.
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JAKne? Systematic review &meta-analysis (25 studies, 10 839 pts), JAK inhibitor use was associated with an elevated odds of acne (OR 3-5 for UPA, TOFA, BARI, Deucra; but higher for abrocitinib (OR 13.5). Seen in Derm pts but hardly at all in Rheum pts https://t.co/XdHmARnxpu https://t.co/N7Bm5GIgjd
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RHEUM Survey: In Newly Dx #PMR patients, How many do you do imaging for GCA vascular involvement?
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Looks like #PMR - But is it?
Patients referred to rheumatologists for suspected PMR - but is it? And what's the role of imaging to help make the diagnosis?
https://t.co/oinfFXE978 https://t.co/4aAHrYbjZD
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Could Methotrexate Work in Hand Osteoarthritis?
Lancet reports the results of the METHODS study from Australia where hand osteoarthritis (HOA) patients benefitted from 6 months of methotrexate (MTX) - as long as there was MRI synovitis!
https://t.co/GhVB7WzJLQ https://t.co/Lt0pvm3RCW
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12.3 million Americans over 50 have osteoporosis; 47 million have osteopenia. W/ OP Fx the risk of repeat Fx is highest in 1st 6 mos, yet 8% of Medicare pts w/ Fx have a diagnostic bone density scan (less in African Americans 5%) https://t.co/2mogEEk3tq https://t.co/9tjwXg0WzZ https://t.co/ruLnjm4kXr
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Tuesday Nite Rheumatology webinar on the use of steroid-sparing drugs in patients with #PMR.
Featuring Panelists: Drs. David Liew, Robert Spiera, Sarah Mackie, Anisha Dua
Moderator: Dr. Sebastian Sattui
https://t.co/HDXCG1bq2m https://t.co/95vfTnXtNP
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Tocilizumab Use in #GCA. In 10 yrs, 114 GCA pts started on TCZ after mean 4.5 mos & Rx for 2.3 yrs. GCA Relapse rates:
- before TCZ 0.84/PY
- on TCZ 0.28/PY (P<0.001)
- post TCZ D/C 0.64/PY
52 pts D/C TCZ after 16.8 mos & 27 (52%) relapsed after 8.4 mo https://t.co/D3INiMdC4U https://t.co/aD2rijR6xd
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Sleep problems in SpA & PsA? Study of 201 pts shows 43% of axSpA and 47% of PsA pts reported sleep problems. In both poor sleep assoc w/ dz activity. In axSpa it signif assoc w/ Dz activity (OR 8.45),biologic use (OR .24), & CRP levels (OR .16) https://t.co/9TEUOODO1P https://t.co/5IhVmOpTCB
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Anifrolumab was studied in 7 adolescents w/ resistant #DLE (discoid); given 6 monthly IV doses. All had signif decreases in skin CLASI-A scores (72%) at 1 month (P =.01), sustained at 6-mo F/U. SLEDAI-2K score also decr by 7 pts; 1 had HSV-1 reactivation https://t.co/Nc0IN1Rsao https://t.co/XeAB99YZMF
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Bimekizumab (Bimelex), a dual IL-17A/F inhibitor, is FDA approved for u Treatment of Adults with Moderate to Severe Plaque Psoriasis https://t.co/IeobNWcM94 https://t.co/OMbhVwFCCt
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#PMR: Ageism, Pain and Drug Management
Dr. Divyani Misra, Boston, discusses ageism, pain and drug management in older adults with polymyalgia rheumatica.
https://t.co/opWAJoF8b3 https://t.co/0JUrdnGa8s
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Learn about enhancing patient care in axSpA through this engaging video series, as Dr Lianne Gensler and Dr Atul Deodhar walk through the updates to the ASAS-EULAR Guidelines. https://t.co/NxGuOXPKjZ https://t.co/HdCGE3ZgpI
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Fever of Unknown Origin
Featuring Dr. Sebastian Sattui (Pittsburgh)
68 yr. old with fatigue and daily fevers of 101F; what's the differential diagnosis?
https://t.co/il6EBLOp0M
#PMR https://t.co/PL5DSdRb1s
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Frailty in #PMR: Why do I need to care?
https://t.co/JYbavonDWL https://t.co/aP97c6zFIH
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Sleep Apnea Smart Watches
Dr. Jack Cush reviews the news, journal reports and regulatory approvals from this past week on RheumNow.
https://t.co/BbBa4JaOV3 https://t.co/vcOxbP6yhQ
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#PMR with Cancer
Dr. Sebastian Sattui (Pittsburgh, PA) Can PMR be a paraneoplastic presentation?
https://t.co/fr2y9VLSMD https://t.co/RsANcK5pbi
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TONIGHT at 7pm ET! Join us for #PMR & Steroid-Sparing Therapeutics featuring panelists Drs. Robert Spiera and Sarah Mackie, and moderator Dr. Sebastian Sattui .
https://t.co/EslrRh7ArO https://t.co/3WY881eDGP
Links:
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