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Biosimilars Match Biologic Originators in Rheumatoid Arthritis
A systematic review and meta-analysis in JAMA Network Open has shown that biosimilars of adalimumab, infliximab, and etanercept were associated with clinically equivalent treatment effects compared with their reference biologics for the treatment of rheumatoid arthritis (RA).
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Time to Risk Stratify Methotrexate Lab Monitoring?
A longitudinal cohort analysis has developed a prognostic model that informs a risk stratified approach to monitoring blood tests during long term methotrexate (MTX) therapy.
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Should we be reassured of JAK safety with new data?
Dr. Janet Pope discusses abstracts OP0133 and OP0132 at EULAR 2023 in Milan, Italy.
https://t.co/Gf4puWXkLY https://t.co/kcnpfEpnTW
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Dr. John Cush RheumNow ( View Tweet)
Still's Disease Abstracts at EULAR 2023
https://t.co/lb1QRcsa9G https://t.co/JIBszS7s7D
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Dr. John Cush RheumNow ( View Tweet)
Watch: IRAEs, Targeted Therapies and Survival
Dr. Aurelie Najm discusses OP0270 presented at EULAR 2023 in Milan, Italy.
@AurelieRheumo
https://t.co/501Rc4SPY1 https://t.co/Ifw93ICqwW
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Dr. John Cush RheumNow ( View Tweet)
Novel drug in development, LY3361237, is a BTLA (B & T lymphocyte attenuator) agonistic antibody to treat autoimmune Dz (eg SLE) - augments immune responses by activating checkpoint inhibitory receptors (CIRs). https://t.co/3iYq9UwHww https://t.co/RwrhqRO8cm https://t.co/tl8qVIXqjc
Dr. John Cush RheumNow ( View Tweet)
Bimekizumab (Bimzelx) has been EMA approved to treat adults with active PsA & axial spondylarthritis in the EU. This dual IL-17 A/F inhibitor is approved to treat moderate -severe plaque psoriasis in the EU, Canada, UK & Japan; but not yet in USA https://t.co/kmjo3HYg4K https://t.co/PINZryXQBP
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Dr. John Cush RheumNow ( View Tweet)
Swedish registry study shows of 3629 children born to mothers with RA#, 70 (1.94%) were diagnosed with Autism Spectrum disorder (ASD). If RA was dx before delivery, an increased risk of ASD (HR = 1.43), especially for seronegative RA (HR = 1.61) https://t.co/6OVZhkTdGc https://t.co/3VHhI7nfQm
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Assessing CV Risk in Inflammatory Arthritis: Which Score?
Dr. Aurelie Najm discusses OP0267 presented at EULAR 2023 in Milan, Italy. @AurelieRheumo
https://t.co/qlJ9iMwrip
@AurelieRheumo https://t.co/Yh2siy6555
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Dr. John Cush RheumNow ( View Tweet)
Abatacept: is there a role before RA hits?
Dr. David Liew discusses OP0130 at EULAR 2023 in Milan, Italy. @drdavidliew
https://t.co/SPLOCjjhUt https://t.co/wkPJLz9ctg
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Dr. John Cush RheumNow ( View Tweet)
ANCA-associated vasculitis: beyond therapy with rituximab?
AAV is a group of multi-system autoimmune small vessel vasculitides which includes GPA, MPA and EGPA.
https://t.co/eZ3mgdjrEp https://t.co/dM9B4tVgmr
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Dr. John Cush RheumNow ( View Tweet)
Methotrexate - an old trusted friend who deserves better
MTX has been used as the anchor drug for the treatment of RA and PsA for many years. It has been co-prescribed with biologics and JAKi in clinical trials and as well as in clinical practice.
https://t.co/xp40KklMkA https://t.co/oVqzlQeqbe
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RheumNow Eular2023 Coverage - SLE Panel Discussion https://t.co/pLWOqZo2aw https://t.co/itAOjgmMTl
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Dr. John Cush RheumNow ( View Tweet)
AOSD: Young vs. Elderly Onset
AOSDis an autoinflammatory condition characterized by fevers, arthritis, and rash. It is considered an orphan disease because of its low prevalence - it is reported anywhere between 16 to 40 per ten million.
https://t.co/fg5TakEvvv https://t.co/lu34gX7WTZ
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Dr. John Cush RheumNow ( View Tweet)
EULAR 2023 Notes from Milan
Dr. Jack Cush reviews highlight abstracts and sessions - covering lupus, RA, gout, Still's disease, safety data, AI in medicine and more - from last week's EULAR 2023 Congress held in Milan, Italy
https://t.co/brcgGv2GHD https://t.co/zVyZkEuLy4
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Dr. John Cush RheumNow ( View Tweet)
Assessing CV Risk in Inflammatory Arthritis: Which Score?
Dr. Aurelie Najm discusses OP0267 presented at EULAR 2023 in Milan, Italy.
https://t.co/MvqkKya4vm
@AurelieRheumo
Links:
Dr. John Cush RheumNow ( View Tweet)
Combining a Tyk2 inhibitor with a JAKi in RA?
Dr. Janet Pope (@Janetbirdope ) weighs in on #EULAR23 abstracts.
https://t.co/7fTZjvnHT3 https://t.co/o43VrWpVpI
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Dr. John Cush RheumNow ( View Tweet)
A step change towards self-empowerment for people living with SLE
As I reflect on my research journey, I recall several issues that still need to be addressed in the management of SLE.
https://t.co/ElunbUgSGF https://t.co/YmA1YWPxVP
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Dr. John Cush RheumNow ( View Tweet)
Postpartum Depression in RA
Dr. Jonathan Kay discusses abstract POS0206-HPR at EULAR 2023 in Milan, Italy.
https://t.co/dzUMIia8Q6 https://t.co/IjeEvz8Cab
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Dr. John Cush RheumNow ( View Tweet)
The Importance of Identifying Central Pain in PsA
Dr. Eric Ruderman discusses abstracts OP0068 and OP0299 at EULAR 2023 in Milan, Italy.
https://t.co/5fjNTrQvNx https://t.co/E1ivkK2bFz
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Dr. John Cush RheumNow ( View Tweet)