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MSK Manifestations in Pediatric IBD
Arthritis and musculoskeletal (MSK) symptoms may accompany pediatric-onset inflammatory bowel diseases (pIBD) as an extra-articular intestinal manifestation, but may vary in presentation and clinical course.
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Mediterranean Diet Efficacy in Psoriasis
A small clinical trial found that a 16-week Mediterranean diet reduced psoriasis severity, presumably due to anti-inflammatory benefits of extra virgin olive oil, plant-based foods, and moderate meat consumption, according to a study published in JAMA Dermatology.
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Eating Crow (10.10.2025)
Dr. Jack Cush reviews the news, FDA approvals, and journal articles. In this episode: HMGCR Abs, FDA approvals and Cush eats crow.
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Whole Body MRI for Arthritis
Whole-body MRI (wbMRI) reviews have increasingly appeared in the medical literature, owing to better scanners, faster imaging times and reduced costs. Used of such non-oncologic musculoskeletal imaging provides high-contrast resolution images of the entire body or selected regions screening, diagnosis, staging, and surveillance purposes.
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Whole Body MRI for Arthritis
Whole-body MRI (wbMRI) reviews have increasingly appeared in the medical literature, owing to better scanners, faster imaging times and reduced costs. Use of such non-oncologic musculoskeletal imaging provides high-contrast resolution images of the https://t.co/6RIrDOwQx2
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Review: Monoclonal Gammopathy of Undetermined Significance
NEJM has reviewed the common hematologic/immunologic finding of "monoclonal gammopathy of undetermined significance" (MGUS) - a common premalignant plasma-cell proliferative disorder found in approximately 5% of those https://t.co/kleuYayTZW
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Rheumatic and musculoskeletal disorders in musicians: Famous musicians/performers with Rheumatic dz and the most common disorders reviewed. https://t.co/FitQpg4KvC https://t.co/ch8V2WGJXm
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Single center study of pregnancy outcomes in 189 women (131 RA, 29 SpA, 29 PsA). Stats for RA/SpA/PsA -- Live births 76%/90%/69%; Preterm 16%/12%/7%; IUGR 31 RA, none in SpA/PsA.. C-Sections ~1/3. TNFi used in 12% RA, but higher in SpA (48%) & PsA (31%) https://t.co/wVWOlRR0c0 https://t.co/sChkDJMrUs
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Multimorbidity in SLE: metanalysis of 3 studies (1175 pts) saw Multimorbidity (by higher Charlson comorbidity index/CCI), is a strong independent predictor of mortality in SLE (OR 3.92). In SLE, the most freq comorbidities were DM, CVD, COPD, renal/lung/CNS Dz https://t.co/fuYUdfC6wE
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Tramadol not effective at chronic pain
The strong opioid painkiller, tramadol, is not that effective at easing chronic pain for which it’s widely prescribed, finds a pooled data analysis of the available research, published online in BMJ Evidence Based Medicine. https://t.co/zFWwyy1j3O
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"It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has." – William Osler
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Review of GLP-1 agonist use in rheumatology - with benefits beyond DM, obesity, improved survival, reduced major cardiovascular and renal events. Anti-inflammatory & chondroprotective effx shown benefit in knee OA & pain. GLP-1RAs do not prevent gout attacks. More research https://t.co/8zh18mlYDh
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FDA has approved nerandomilast (PDE4b inhibitor) for treatment of adults with idiopathic pulmonary fibrosis (IPF). Approval is based on 2 RCTs, FIBRONEER-IPF & FIBRONEER-ILD, that show slowing of lung function decline IP & progressive pulmonary fibrosis (PPF) pts. https://t.co/pIQwyLUBoj
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Sequencing DNA to find new lupus treatments
MUSC geneticist Betty Tsao, Ph.D., will lead a five-year project to identify rare mutations associated with childhood-onset SLE, or lupus, with more than $3.5 million in funding from the National Institute of Arthritis and https://t.co/1vfQ4fK6FX
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Systematic review of obesity management meds - 56 RCTs (60,307 pts). All OMMs were better at total weight loss than PBO (P < 0.0001), >10% semaglutide & tirzepatide (both effective at NIDDM CHF). Semaglutide effective reducing pain in knee osteoarthritis https://t.co/4MX2IiDC2X
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Activity Trackers Can Predict RA Flares
People with rheumatoid arthritis (RA) who experienced disease flares often showed changes in heart rate and physical activity captured by popular wearable devices 4 weeks before they became clinically apparent, a small study indicated. https://t.co/LjE0LkJTrB
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Taiwan study of HBV or HCV reactivation w/ bDMARD use in PsO & PsA - among 5527 treatment episodes (3197 ts/bDMARDs) found a 10% risk of reactivation of HBVr (10.6%) & HCV (9.9%), highest w/ TNFi. Reactivation assoc w/ TNFi, HBsAg+, HBeAg+, immunosuppressant use without antiviral https://t.co/AwpmRpfJUT
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NY Times on Osteoporosis in Men
The NY Times has addressed the problem of osteoporosis in men noting a need for increased awareness and screening...
Read more: https://t.co/SzNtuPllY6 https://t.co/13EcEfv4ab
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Gender Complexities in Psoriatic Arthritis Treatment Outcomes
Analysis of a German psoriatic arthritis (PsA) patients registry demonstrates sex-specific differences regarding clinical manifestation and treatment outcomes, especially with regard to drug discontinuations. https://t.co/zGtfpndod9
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From the plenary to posters, RheumNow is your companion for ACR Convergence 2025. Expect:
• KOL videos
• Clinical trial highlights
• Daily faculty recaps
• Live streaming
#ACR25 #Rheumatology #ClinicalTrials https://t.co/M5sxhWz2EK
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