Chikungunya Club Meeting (7.24.2026)
Dr. Jack Cush reviews the news, journal reports from the past week on RheumNow.com.
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Evidence-Based Dietary Recommendations for Gout
Gout, historically referred to as the “disease of kings,” was once associated with a lifestyle of excess, including ready access to alcohol and rich meats once reserved for society’s highest ranks. Today, it is more appropriate to refer to gout as a “disease of commoners,” as it is
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QD Clinic: Gout: Is it the Journey or the Destination?
Dr. Arthur Kavanaugh discusses a gout patient whose frequent flares improved after lifestyle changes, despite medication not being enough on its own.
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Dr. John Cush @RheumNow( View Tweet )
Predicting and Managing Gout Flares in Hospitalized Patients
Dr. Kanon Jatuworapruk, Bangkok, discusses predicting and managing gout flares in hospitalized patients as part of RheumNow's "Gout: More than Flares" campaign in July 2026.
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Dr. John Cush @RheumNow( View Tweet )
Allopurinol - severe allergic reactions are estimated at 0.4%-2%, rising to 8–18% in patients with chronic kidney disease. Being HLA-B*58:01 (+) dramatically increases risk (OR 117).
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Genetic study of 16 pts w/ Allopurinol-induced severe cutaneous adverse Rxn (SJS/TEN) shows 2 class I alleles to be associated: HLA-B*58:01 (OR, 28.0 [95% CI, 8.6-100.6]) and HLA-A*34:02 (OR, 20.6 [95% CI, 3.3-131.1]). Both explain 80% risk in US pts https://t.co/OxDXuWCbup https://t.co/oky61JImQV
Dr. John Cush @RheumNow( View Tweet )
Gout master class @RheumNow
Upgrading & Maximizing the Classics (Colchicine, Allopurinol, etc.) https://t.co/yvSkULQlyR via @YouTube
Nouf Al hemmadi @NoufAhmedAlham2( View Tweet )
Persistence of education and monitoring is crucial to optimal gout management
It is important that the misconceptions and myths held by the patient are discussed and dispelled and, most importantly, establish a clear understanding of “the plan” and the reason for initiating urate-lowering therapy (ULT).
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Gout patients are at greater risk for dementia, sleep apnea, septic arthritis and erectile dysfunction.
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Dr. John Cush @RheumNow( View Tweet )
The Marriage between Gout and the Kidney
While the link between uric acid and gout was first described by Alfred Baring Garrod in the 1800s, the proof that uric acid might actually be the cause had to await the self-experimentation of two rheumatologists from the University of https://t.co/AWZbjaUtdu
Dr. John Cush @RheumNow( View Tweet )
SGLT2i use in gout reduces use of gout meds. Study of 26,739 gout pts w/ NIDDM (mean 66 yrs), 67% w/ polypharmacy. SGLT2i (vs DPP-4i) user had less Allopurinol starts (HR 0.62;0.52–0.73), also lower use of steroids (,78), NSAID (.85), colchicine (.87) & diuretics (.87) https://t.co/1dW27YzSvg
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Pragmatism in Gout: How therapeutic choices can have multiple benefits
William James famously wrote in Pragmatism, “There can be no difference anywhere that doesn’t make a difference elsewhere.” Gout treatment offers a striking medical example of that idea. Drugs prescribed to calm flares or lower uric acid are designed with one primary goal in
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Gout in Minority Populations
Recent research has revealed substantial racial and ethnic disparities in both who develops gout and the care patients receive. These differences reflect not only genetic susceptibility but also the substantial influence of social determinants of https://t.co/SKEsQVZPw6
Dr. John Cush @RheumNow( View Tweet )
Low dose ASA (81mg or 325mg) increase gout attacks by 81% (RR 1.81). Effect nullified by allopurinol use.
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Dr. John Cush @RheumNow( View Tweet )
The Hidden Cost of Gout
For many people, gout is viewed as an episodic disease: a painful flare, a short course of treatment, and then life returns to normal. However, as rheumatologists, we know that recurrent attacks can lead to joint damage and tophi if left untreated. Furthermore, the true burden of gout extends
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Gout TRUST trial compared gout flares in 28 pts assessed biweekly electronically or by phone. Over 12 wk (109 flare periods, 108 electronic & 99 phone assessments) there were 23 flares on electronic surveys and 22 flares on phone surveys (96% agreement; strong concordance, ICC https://t.co/fugYIasf4G
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Why Do Gout Flares Start at Night?
The striking propensity for gout flares to initiate at night has been recognized for centuries. More recent epidemiological research supports this observation, indicating that the risk of a gout flare is more than twice as high in the early https://t.co/FbCUmXEl2y
Dr. John Cush @RheumNow( View Tweet )
Rheumatoid arthritis is found in 2-3.8% of gout patients.
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QD Clinic: Allopurinol for All Gout? Not Quite
Dr. Brian Jaros, Chicago, discusses the use of allopurinol.
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Dr. John Cush @RheumNow( View Tweet )
QD Clinic: When There's Doubt in Gout
Dr. Eric Dein discusses how imaging was used in correctly diagnosing a mid-foot symptom in gout.
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Dr. John Cush @RheumNow( View Tweet )
Seronegative RA Disease Activity (7.17.2026)
Dr. Jack Cush reviews the news, journal articles and Gout features from this past week on RheumNow.com.
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Gout Imaging in Care
Gout is all about the crystals and the consequences of the disease are due to the inflammation they cause. Getting rid of urate crystals is the ultimate goal in gout, as we now know that it leads to the risk zero of flares and it normalizes the https://t.co/DGuiTOtQFa
Dr. John Cush @RheumNow( View Tweet )
Saliva and Uric Acid Testing
A recent report from China reaffirms the potential utility of salivary uric acid (UA) testing delivers smartphone-guided, enzyme-free gout screening at home for pennies per test.
https://t.co/VtvJuPNEWA https://t.co/pdBmy5JoQd
Dr. John Cush @RheumNow( View Tweet )
Four Things About Allopurinol Hypersensitivity Syndrome
Dr. Robert Terkeltaub discusses allopurinol hypersensitivity syndrome in gout patients.
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Dr. John Cush @RheumNow( View Tweet )
The Marriage between Gout and the Kidney
While the link between uric acid and gout was first described by Alfred Baring Garrod in the 1800s, the proof that uric acid might actually be the cause had to await the self-experimentation of two rheumatologists from the University of Pennsylvania. Given some comments that the presence of
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Watch our 'Systemic Burden of Gout' series as part of this month's Gout More than Flares campaign. Check out our videos including: Genome-Wide Association Studies in Gout, Gout and Cardiovascular Disease and Gout & Obesity.
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Daily Gem
Gout, unlike any other disease, kills more rich men than poor, more wise men than simple.
-- Thomas Sydenham
Campaign Videos
Podcasts
What Lies Beneath - Uric Acid Deposition & Imaging
Gout QD clinics - lessons from the Clinic QD307-QD311
Gout Journal Club