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ACR Promotes New COVID-19 Vaccine Clinical Guidance for Rheumatic Patients
The American College of Rheumatology has published a draft guidance on the use of COVID-19 vaccination in rheumatic disease and musculoskeletal disease patients, based on the efforts of the North American Task force. The document provides guidance to rheumatology providers on the use of the COVID-19 vaccine and the associated management of RMD patients around the time of vaccination. Here is a summary of the recommendations.
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2020 Rheumatology Year in Review
2020 was historic, memorable and game-changing. Under the cloud of COVID-19, there were many significant and memorable advances and setbacks for the rheumatology world. In our accounting of most read articles for 2020, (not surprisingly) 17/20 were COVID-related.
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Rhapsody Study: IL-1 Inhibition in Recurrent Pericarditis
Recurrent pericarditis is a rare, probable autoinflammatory disorder mediated by interleukin-1 (IL-1); and is often refractory to glucocorticoids and colchicine.
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ACR 2020 Reproductive Guidelines - Lactation Guidance (Best of 2020)
In this third excerpt from the ACR guidelines on managing reproductive health issues in rheumatic disease patients, we present recommendations regarding the use of glucocorticoids and guidance on lactation and medication use post-partum.
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PFAPA does not have a genetic dx (yet). But she's sure increase in IL - 12 p70, this making apremilast and ustekinumab potential therapy for difficult cases. @RWCSmtg https://t.co/gdz7d5KCrm
PFAPA may be part of a spectrum the includes Behcets @rwcs https://t.co/wmX76bFPX2
PFAPA (aka Marshall syndrome) also occurs in adults @RWCSmtg https://t.co/52NVpKGCzP
Dr. Susan Shenoy @rwcs shows discovery of autoinflammatory diseases began w MEFV genes (FMF) in 1997, followed by genes for TRAPS and HIDS in 1999. @ https://t.co/sG4BlK1zhR
Not just Juvenile: Adult Onset Still's Disease Complicated by Macrophage Activation Syndrome RWCS 2021 Poster Session by Dr. Eric Seronick, UC-Irvine https://t.co/p9DsTu8kBK
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Dr. John Cush RheumNow ( View Tweet)
QD Clinic - Fever by the Numbers Diagnosis of Periodic Fever by Fever Duration https://t.co/q3ZmJLrgOO
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Dr. John Cush RheumNow ( View Tweet)
Defects in NLRC4 inflammasome can drive IL 18 production in systemic JIA. @RWCSmtg https://t.co/ffzODTXd52
Colchicine suppresses MSU & CA pyrophosphate crystal activation of Nod-Like Receptor Protein 3 (NLRP3) inflammasome, thereby suppressing caspase-1 activation and the subsequent release of IL-1β and IL-18. Great review by Pillinger et al https://t.co/n7MHtSviT5
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Dr. John Cush RheumNow ( View Tweet)
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Dr. John Cush RheumNow ( View Tweet)
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Autoinflammatory & Still's Disease Panel #acr20 Dr. Jack Cush leads a panel of experts regarding Still's Disease and ACR 2020. https://t.co/4GmM56l1cb https://t.co/WbXMUtz6Up
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#BestACR20Tweets RT @KDAO2011 : #FDA updates 6/16/20 canakinumab for AOSD 5/29/20 ixekizumab for nr-AxSpa 80 mg q4wks 3/9/20 nintedanib for progressive ILD 1/29/20 and 6/16/20 secukinumab nr-axSpa 150 mg q4wks, AS 300 mg SQ q4weeks 1/17/20 belimumab label for black pts removed
Dr. John Cush RheumNow ( View Tweet)
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