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Should we be measuring HCQ levels?
- note HCQ doses should be reconsidered in pts with CKD stage >2 w/ 4 fold higher odds of HCQ levels
- adjust dose for pts with renal impairment
@RheumNow #RNL2023 https://t.co/JvaRJKJRPv
Robert B Chao, MD doctorRBC ( View Tweet)
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#RNL2023 Year in Review
BE COMPLETE: P3 trial Bimekizumab for PsA in TNF inadequate responses at 16 weeks
160 mg BKZ SQ q4w vs PBO
ACR50 43%, PBO 7%
PASI 1000: BKZ 58.5% vs PBO 4.5%
Safety: oral candidiasis: 2.6% BKZ vs PBO 0%
@RheumNow https://t.co/bW00Wg6Cnf
Eric Dein ericdeinmd ( View Tweet)
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Talk to me about candidiasis. BKZ showed increased safety signals for candida infections. I fear infxns may be under reported (after approval and in use) if patients see other physicians for treatment vs their rheumatologist/derm. Thoughts on this signal? #RNL2023 @rheumnow https://t.co/UPA5oP9G49
Dr. Rachel Tate uptoTate ( View Tweet)
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Could MTX every other week dosing be an option in patients with stable disease..?
#RNL2023 https://t.co/EZRdQnuXjy
Dr Gurdeep Dulay gurdeep_dulay ( View Tweet)
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Urinary biomarkers in lupus nephritis
@RheumNow and Kavanaugh discusses new urinary biomarkers in lupus nephritis that correlates with histology!
#RNL2023 https://t.co/l1gQgFhviI
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
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Year in Review by Dr. Cush and Dr. Kavanaugh
Combo biologic therapy?
Phase II study from GI colleagues for UC
Guselkumab + golimumab
- no additional safety concerns
- improved clinical response
- extrapolate to rheumatology use?
#RNL2023 @RheumNow https://t.co/DirAovm1AX
Robert B Chao, MD doctorRBC ( View Tweet)
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✅ RheumNow Live 2023
#RNL2023 @RheumNow
Which adverse events ⬇️ can be expected by patients & their rheumatologists when using #hydroxychloroquine for #Lupus? https://t.co/9zP8aJ4cGq
Laurent ARNAUD Lupusreference ( View Tweet)
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TYK2 in plaque psoriasis By Eric Ruderman #RNL2023 @RheumNow
Safer?
No lab monitoring
And it works https://t.co/9Woen2q4hZ
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
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Beautiful summary of GPA management by Dr.Carol Langford #RNL2023 @RheumNow https://t.co/FCwKN9tovX
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
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PMR lab studies by @anisha_dua @RheumNow #RNL2023
Majority of patients will have elevated inflammatory markers.
Rapid clinical response to low dose of steroid. https://t.co/AgdIJ5YbOu
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
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Some points to consider in relapsing PMR , by @anisha_dua @RheumNow #RNL2023
Elevated ESR and CRP rule out GCA.
Relapses are common with steroid tapering, especially below 5mg. https://t.co/D17mdly7z5
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
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Long live the GOAT Rx: MTX 🐐🐐
History of usage dating back to 1950
Use 1st-line
Optimize dose
Supplement folic acid
Split dose
Give SQ
Use in combination therapy
Dr Joel Kremer #RNL2023 @RheumNow https://t.co/CCBvQoNHXo
Eric Dein ericdeinmd ( View Tweet)
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#ClinicalPearl #Methotrexate weekly May reduce side effects in rapidly dividing cells vs using it daily or every few days. GI, oral, bone marrow side effects should be less if once a week. Joel Kremer @RheumNow #RNL2023 https://t.co/i0LZoQuK0w
Janet Pope Janetbirdope ( View Tweet)
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TYK2 signalling Vs JAK signalling summary
#RNL2023 https://t.co/0VNBiEc6jq
Dr Gurdeep Dulay gurdeep_dulay ( View Tweet)
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Approach to pregnancy in patients with PsA , By Dr.Chambers #RNL2023 @RheumNow https://t.co/8tSz7qbmQU
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
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Prevalence of PsA in women of reproductive age, By Dr.Chambers #RNL2023 @RheumNow https://t.co/hB6QQtz7fw
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
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Dr. Laura Coates on PsA treatment:
- Applying treat to target associated with better quality of life
- low disease activity is a reasonable target
Do you use PROs in managing your PsA pts? Perhaps we should
@RheumNow #RNL2023 https://t.co/36n1Cp5jtP
Robert B Chao, MD doctorRBC ( View Tweet)
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Why do PROs matter? @DrLauraCoates reviewed this slide regarding the increased survival curve in end-stage cancer patients when we monitor PROs. @RheumNow #RNL2023 https://t.co/JfHNBKJGRl
Dr. Rachel Tate uptoTate ( View Tweet)
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Dr.Robert Spiera approach to GCA #RNL2023 @RheumNow https://t.co/ublzYwBbIF
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
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Steroid sparing agents in GCA , what worked? By Dr.Robert Spiera #RNL2023 @RheumNow https://t.co/7Q9UYRSAhR
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)