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Depression and anxiety in PsA is higher and has more consequences than in general population
Swedish and Danish clinical registers 23000+ PsA pts
HR 1.4 specialised psychiatric out/ inpatient care vs. general pop
HR for psychiatric in patient care numerically higher but ns.
No https://t.co/qduMcwGK0S
Aurelie Najm AurelieRheumo ( View Tweet)
Prediction of PsA in PSO pts: does it work?
First predictive model using mainly clinical data and labs extracted from primary care
Performs well in the cohort it was trained w/ but not in validation cohort.
Often an issue with prediction models!
Needs more granularity than https://t.co/5cVgqfd4fX
Aurelie Najm AurelieRheumo ( View Tweet)
‼️Diagnosis of axSpA is clinical
-MRI is a tool but still has a lot of limitations.
-Improve reports by directly communicating with radiology and be specific on pt clinical info.
-Unified algorithms are needed to apply AI in dx of SIJ inflammation on MRI.
#EULAR2025 @RheumNow https://t.co/9GR6FsgIcL
Links:
Adela Castro AdelaCastro222 ( View Tweet)
Is #PDE5i protective in development of
#SSc #ILD?
Maybe
444 w ILD of >4000 #EUSTAR Pts over 1 to 2 yrs f/u
#immunesuppressive use maybe or not
🤷♀️channeling bias
Reduction in new #ILD in #scleroderma
PDE5i ✅
Immunesuppression ?
@RheumNow #EULAR2025 @eular_org #OP0334 https://t.co/6dtLfybkRV
Links:
Janet Pope Janetbirdope ( View Tweet)
#EULAR2025 Take Home message from Updated EULAR Recommendations @eular_org for #Lupus Nephritis:
-Kidney Biopsy vital
-Early use of Combination Therapies (HCQ + GC + Immunosuppressant + CNI/Belimumab/Obinutuzumab)
-Severe: High dose Cyclo + GC
@RheumNow https://t.co/jHFqdT1TLf
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Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
🔍MRI lesions in early axSpA vs non axSpA with chronic back pain:
-Data from SPACE cohort
-n 318 (214 axSpA vs 108 non-axSpA).
-Baseline imaging (CR and MRI) and at 2y f/u
-Minimal progression on CR in both early axSpA and non-axSpA CBP.
-On MRI, significant increase in the https://t.co/m5YOAiFUz1
Links:
Adela Castro AdelaCastro222 ( View Tweet)
E3N cohort 78000+ women >30yrs follow up
698 incident RA cases)
In non smokers, RA asso w/
-tall at birth HR=1.55
In smokers, RA risk associated w/
-prematurity HR=1.63
-in utero exposure to tobacco HR=1.83 (ns)
#EULAR2025 @RheumNow POS0226 https://t.co/xC3k3kiKsZ
Aurelie Najm AurelieRheumo ( View Tweet)
PsA asso w/ higher risk of preterm births in women
Scandinavian registries
688 PsA pregnancies
8% preterm births vs. 4.5% general population OR 1.8
16.4% if bDMARD combination OR 4
3.1% if bDMARD monotherapy OR 0.7
bDMARDs combo probably a surrogate of high disease activity
Aurelie Najm AurelieRheumo ( View Tweet)
Difficult-to-Manage AxSpA: Global Prevalence and Associated Factors
The concept of D2M axSpA is a recent development, with the first expert consensus definition published by the Assessment of SpondyloArthritis International Society (ASAS) earlier this year. https://t.co/KmfJvAtwp0
Dr. John Cush RheumNow ( View Tweet)
RheumNow’s expanded coverage of the #EULAR2025 Annual meeting is sponsored in part by Johnson & Johnson and UCB. All content chosen by RheumNow & its Faculty.
Dr. John Cush RheumNow ( View Tweet)
Live Daily Eular 2025 Recap Day 2 https://t.co/78NYTcFPG6
Links:
Dr. John Cush RheumNow ( View Tweet)
Secukinumab promise in PMR is real
GCA is getting steroid-sparing therapy choices, and PMR doesn’t want to miss out. Most PMR patients with current therapy approaches incur multiple grams of cumulative prednisolone exposure, even though they’re often exactly the kind of https://t.co/GuD0l7zSfj
Dr. John Cush RheumNow ( View Tweet)
Among 200 #axSpA pts from Rheumazentrum Ruhrgebiet
🔴Performance tests (SPPB)
were associated with
🔴Global functioning and health (ASAS-HI and other PROs)
What does this mean?
Improving physical performance could enhance PROs & QOL
#EULAR2025
POS#
@RheumNow
@XBaraliakos https://t.co/P3Q5NDvtoj
Nelly ZIADE 🍀 Nellziade ( View Tweet)
#D2M_axSpA_saga 🇬🇷
Prevalence of D2M axSpA in 395 patients: 10.1%
Associated factors:
🔹️High disease activity at diagnosis
🔹️Comorbidities (high BMI, smoking, depression)
🔹️Unemployment
Kougkas et al.
POS#0121
#EULAR2025
@rheumnow https://t.co/vcPcTATTx5
Nelly ZIADE 🍀 Nellziade ( View Tweet)
What's the difference between PIPsA & NIPsA?
(Persistent Inflammatory confirmed by IMAGING
vs. Non inflammatory PsA)
🔹️Cross-sectional study
🔹️517 pts under b/tsDMARDs
🔹️10.3% D2T
🔹️57% PIPsA / 43% NIPsA
👇 Distinct phenotypes 👇
OP0176
#EULAR2025
@rheumnow https://t.co/YGHpbeE6ws
Nelly ZIADE 🍀 Nellziade ( View Tweet)
What happens to the prevalence of D2T PsA if we use different parameters in its definition?
Data from 5 Nordic registries including 13,872 patients showed a variation from 37% (less stringent) to 0.6% (more stringent)!
OP0177
#EULAR2025
@rheumnow https://t.co/QbF15t3Zrz
Nelly ZIADE 🍀 Nellziade ( View Tweet)
#EULAR2025 Abstr#OP0319 Multicentre study in Canada showed no difference in longterm Lung Transplant outcomes among IIM-ILD, SSc-ILD & IPF. Some differences: IIM-ILD was progressive pre-transplant with prolonged hospitalisation post-surgery. For us to be aware @RheumNow https://t.co/eFdY4XGtlj
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
🚨Diagnostic delays are real in axSpA:
-Can lead to more extra-msk manfieststions (EMMs) in PsA and axSpA.
-Increases disease burden and productivity losses.
-EMMs can present before articular sx
-Uveitis and IBD associated with longer dx delays.
-Diagnosis has improved since https://t.co/rWMwG7Ewwe
Links:
Adela Castro AdelaCastro222 ( View Tweet)
#guidelines everywhere
@jeffsparks presents points of interest from #ACR #ILD #recommendations
- a joint venture with American College of Chest Physicians
While simultaneously the EULAR ILD recommendations are being unveiled!
@RheumNow #EULAR2025 @eular_org @ACRheum https://t.co/cfHrqIAbx9
Links:
Janet Pope Janetbirdope ( View Tweet)
A machine learning (ML) model using electronic medical record (EMR) data from 396,000 Mayo Clinic primary care patients identified undiagnosed psoriatic arthritis (PsA) with area under the curve (AUC) 79.6%. Key predictors: psoriasis, joint pain, tenosynovitis, https://t.co/VsYevnJEjK
Antoni Chan MD (Prof) synovialjoints ( View Tweet)
