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RECITAL Trial: RTX vs. CTX in CTD-ILD
A UK study suggests the equivalent outcomes when patients with interstitial lung disease (ILD) associated with connective tissue disease (CTD) are treated with either intravenous rituximab (RTX) or cyclophosphamide (CTX), but with fewer adverse events with RTX.
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Just Can’t Get Enough of Hydroxychloroquine
When it comes to hydroxychloroquine dosing, issues on efficacy, toxicity and therapeutic thresholds may affect the optimal use of this important drug.
Following are three abstracts presented during the meeting that address these topics.
Steroid injections worsen knee arthritis
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EurekAlert!
Two studies comparing injections commonly used to relieve the pain of knee osteoarthritis found that corticosteroid injections were associated with the progression of the disease.
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A great read from Dr. Anthony Fauci as he steps down from leading the NIH NIAID research for nearly 40 years. He writes on pundits, need for specialty growth, evolution of vaccines and "it aint over till its over" is now "its never over" https://t.co/z0noGckIvx https://t.co/DJKG88V1mc
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Dr. John Cush RheumNow ( View Tweet)
Estimated worldwide market for DMARDs in 2022 was $20.7 billion USD and is expected to rise at a 3.5% annual growth rate to $ 272 billion USD by 2030 https://t.co/futp7249rF https://t.co/QgxJR7TQNw
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The Great Debate: To Treat or Not to Treat Pre RA
Dr. Janet Pope ( @Janetbirdope) and Dr. Jonathan Kay ( @RheumKay) discuss the Great Debate, which Dr. Pope participated in, at #ACR22.
https://t.co/PPXiX8MG6m https://t.co/Uy0kQd7XGz
Links:
Dr. John Cush RheumNow ( View Tweet)
Fertility issues in SpA
Dr. Sheila Reyes ( @RHEUMarampa) speaks with Dr. Sabrina Hamroun about abstract 1673 at #ACR22.
https://t.co/SvCuE4fx04 https://t.co/DAveKT29J8
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Dr. John Cush RheumNow ( View Tweet)
Does Race play a role in Mycophenolate Response in Scleroderma
Dr. Eric Dein ( @ericdeinmd) speaks with Dr. Lauren Smith about abstract 0521 at #ACR22.
https://t.co/3lcVjfMsub https://t.co/P3XcsiXgWa
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Dr. John Cush RheumNow ( View Tweet)
Copays Reduce Adherence to SLE Medications
Dr. Michael Putman ( @EBRheum) reports on abstract 1115 at #ACR22 Convergence in Philadelphia, PA.
https://t.co/VLyMTSLFCf https://t.co/0nOA0b1576
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Dr. John Cush RheumNow ( View Tweet)
Proceedings of the Royal Society of Medicine and Fibromyalgia Action UK Webinar: Fibromyalgia in the 21st century: Redefining care. https://t.co/6k4Thx4ZSN https://t.co/1TfapVGMoe
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Dr. John Cush RheumNow ( View Tweet)
Study of 1207 joints in 55 RA pts shows that Xray progression over 2 yrs is significantly assoc w/ US Power Doppler (OR 2.92), erosions (OR 4.74), but also with Joint tenderness w/o swelling (OR 1.85) ! (Less signif w/ PsA) https://t.co/gue5jt6Xdx https://t.co/vhFBWTgEHW
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Dr. John Cush RheumNow ( View Tweet)
Mayo LUMEN study looked at SLE nephritis incidence betw 1976 -2018, & showed that LN increased over past 4 decades. LN patients have poor outcomes w/ higer rates of ESRD & mortality rates (SMR 6.33); @10 yr survival =70% & 13% ESRD https://t.co/QDDTORSgyZ https://t.co/89ldzxhuMk
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Dr. John Cush RheumNow ( View Tweet)
Thinking Outside the Box: Novel Strategies for Early Detection of AxSpA
Early diagnosis of AxSpA remains a challenge. Strategies to identify patients with suspected inflammatory back pain in the general population is critical.
https://t.co/LsKOOHDOJI https://t.co/NARG61vBSn
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Dr. John Cush RheumNow ( View Tweet)
Dual inhibition of IL17A and IL17F in AxSpA
https://t.co/OvzQnYw7dH https://t.co/qkCsyBofDJ
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Dr. John Cush RheumNow ( View Tweet)
Do different genders experience PsA differently?
There has been a lot of talk lately about the difference in the way male and female PsA patients experience their disease.
Dr. Petryna ( @DrPetryna) weighs in. #ACR22
https://t.co/nPHf2fR6gQ https://t.co/CcO2gwgh3Y
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Dr. John Cush RheumNow ( View Tweet)
Advancing Telehealth in Rheumatology #ACR22
https://t.co/TZL2ZHVTax https://t.co/4Z5Sbvpo23
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Dr. John Cush RheumNow ( View Tweet)
mTORC1 as a Driver of Inflammation in sJIA Connecting Pathogens of sJIA and MAS
Dr. Olga Petryna discusses Abstract 0004 presented at #ACR22
Abstract 0004: mTORC1 Drives the Spectrum of Pathology in Systemic JIA and Macrophage Activation Syndrome
https://t.co/XLbchHGG6w https://t.co/h5KArPYrPZ
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Dr. John Cush RheumNow ( View Tweet)
Can you use the BASDAI in Pregnancy?
Dr. Eric Dein ( @ericdeinmd) discusses abstract 0374 presented at #ACR22 Convergence in Philadelphia, PA. Abstract 0374: The BASDAI Index During Pregnancy.
https://t.co/UB8ZGyQ6mz https://t.co/tkr6cOIMD9
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Dr. John Cush RheumNow ( View Tweet)
Vaccine Efficacy in Patients with Seronegative SpA
Vaccine efficacy remains an important topic at #ACR22 given the ongoing COVID-19 health crisis, current influenza season, and recently published 2022 ACR guidelines.
https://t.co/2PHrJYV8Om
Written by Dr. Sims ( @DrCassySims) https://t.co/hUFnPIDzUU
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Dr. John Cush RheumNow ( View Tweet)
Can we accurately capture disease activity in pregnant patients with AS?
Dr. Aurelie Najm ( @AurelieRheumo) discusses Abstract 0374. #ACR22
https://t.co/oafV1BP91X https://t.co/wMelZm5iOj
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Dr. John Cush RheumNow ( View Tweet)