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A meta-analysis of 11 randomized trials shows no significant difference in efficacy of bDMARDs for early vs. established axial spondyloarthritis (axSpA). Treating at different stages yields comparable short-term outcomes. Abstr#1468 #Spondyloarthritis #RheumatologyResearch… https://t.co/QYuTcVj2m1 https://t.co/ADzEEbCvUM
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Antoni Chan MD (Prof) synovialjoints ( View Tweet)
@ACRheumDC State Update:
No changes at executive level
Some shifts in state legislation
With political changes and new administration, states will probably take larger role in healthcare legislation
- PBM reform, copay accum, prior auth/step, reprod healthcare
@RheumNow #ACR24 https://t.co/jc77HCLxqQ
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Eric Dein ericdeinmd ( View Tweet)
State Update @ACRheumDC
No executive level changes, some state legislative flips
Political changes will likely lead to more state legislative healthcare legislation
- In the works for PBM reform, copay accum, prior auth/Step, reprod healthcare
@RheumNow #ACR24 https://t.co/94KyHU0Blr
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Eric Dein ericdeinmd ( View Tweet)
#1326
🔬 Predicting Imminent Inflammatory Arthritis
➡️543 anti-CCP+ at-risk (high/low) tracked
🔑Predictors for IA in high-risk:
🔴EMS≥30min(OR 11)
🔴RF+(OR 6)
🔴US PD(OR 5)
🔴smJTC (OR 5)
🔑Predictors for IA in low risk:
🔴RF+(OR 8)
🔴Anti CCP >3xULN(OR 7)
#ACR24 @RheumNow https://t.co/ou9HNcNb8X
Caoilfhionn Connolly CaoilfhionnMD ( View Tweet)
What is Osteoarthritis? A downloadable patient education page from JAMA. https://t.co/pQgGfI0boe https://t.co/pd3kygUxkH
Dr. John Cush RheumNow ( View Tweet)
Dietary changes are intermittent fasting are common in axial spondylarthritis (axSpA) patients, possibly reducing inflammation. A study found 55% currently on a diet and 31% fasting. Many believe these practices improve disease activity. Abstr#1459 #diet #axSpA @RheumNow #ACR24
Antoni Chan MD (Prof) synovialjoints ( View Tweet)
Regulatory update @ACRheumDC
Inflation Reduction
Planned decrease in 10 drug prices including ETN
Expect this may be gutted by new administration. Will follow and advocate for drug pricing
@RheumNow #ACR24 https://t.co/ZrcMaLD6tu
Links:
Eric Dein ericdeinmd ( View Tweet)
Harkins @DrTrishHarkins et al. Novel diagnostic cytokines in treatment naive PMR. Elevations CXCL-9 (100%), MCP-1 (93%), IL-17A (83%), vs TNF (7%) and IL-6 (67%) @RheumNow #ACR24 Abstr#0881 https://t.co/DbYOn81QJH https://t.co/3eyre00D5d
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Richard Conway RichardPAConway ( View Tweet)
119 Congress - prepare for change
Obamacare subsidies set to expire
NIH changes and possible reorg
ACR champions are in gov positions for both parties
Focus on affecting change that is practical, possible and improves rheumatology practice
@ACRheumDC @LennMcD
@RheumNow #ACR24 https://t.co/tcxixdlSWQ
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Eric Dein ericdeinmd ( View Tweet)
@LennMcD @ACRheumDC
Do policies affect medication access, costs, reimbursements, telehealth, or your life as a rheumatology provider or patients?
Contact - quick and easy!
https://t.co/TvMlXiIZQR
@RheumNow #ACR24 https://t.co/plnUtl7Kml https://t.co/lFGx7hzlKy
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Eric Dein ericdeinmd ( View Tweet)
#Blinded by results? 😊
#Ocular #involvement in #GPA
👇
Helped by #rituximab
👁️ #GPA
Difficult
Proptosis
Pseudotumour
Conjunctivitis
Scleritis
Vasculitis
Ocular muscles - diplopia
Small case series ‘author defined’ remission in
80% 👍 #RTX
#abst0726 @rheumnow #ACR24 https://t.co/GHptelOTyv
Janet Pope Janetbirdope ( View Tweet)
If high +ANA and NO #rheumatic #disease LOOK 👀 at #LIVER #Autoimmune #hepatitis And #alcoholic #liver #dx #ACRBest #ACR24 @rheumnow abst#0627 https://t.co/EVLUyvpBfD
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Janet Pope Janetbirdope ( View Tweet)
Improved fertility in women with RA when treated with a Treat-to-Target (T2T) approach aimed at remission.
Key findings:
- Shorter time to pregnancy (TTP) in PreCARA cohort (84 days) vs. PARA cohort (196 days).
- Increased TNF-inhibitor use and lower NSAID/prednisone use in the… https://t.co/YyD2lpXVRC https://t.co/LH5LMOH8al
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Antoni Chan MD (Prof) synovialjoints ( View Tweet)
@ACRheumDC
Check out the ACR policy position statements
Created by volunteer-led, non-partisan group of GAC committee - changes based on the needs of the ACR members
@cdowneymd
https://t.co/oAFfYUct4y
@RheumNow #ACR24 https://t.co/MmVd8XYs0j
Links:
Eric Dein ericdeinmd ( View Tweet)
Half of the respondents chose #IL17i for #psoriatic #arthritis #PsA Rx for #Achilles #tendonitis
Interesting as lots
Of data
On #enthesitis wIL23i
Likely all
Effective #PsA Rx helps #tenosynovitis
some have
➡️ data on #efficacy
⬆️ bio rationale
#ACR24 @RheumNow @ACRheum https://t.co/wzefjsfdaj
Janet Pope Janetbirdope ( View Tweet)
If you are not at the table, you are on the menu
https://t.co/c4anIn3aue
@cdowneymd @ACRheumDC
Join a committee
RheumPAC
Write a letter
Write a post card at ACR Hub at #ACR24
Advocacy office hours with ACR staff
#Act4Arthritis & Advocacy 101 on Cap Hill
@RheumNow https://t.co/bpilydxEpB
Links:
Eric Dein ericdeinmd ( View Tweet)
The post hoc analysis of the SURPASS study evaluated predictors of radiographic spinal progression in axial spondyloarthritis patients treated with IL-17A (secukinumab) or TNF inhibitors over 2 years.
Key findings:
- New syndesmophytes: 18.2% (SEC 150 mg), 15.8% (SEC 300 mg),… https://t.co/jke6OHdPjZ
Antoni Chan MD (Prof) synovialjoints ( View Tweet)
The future use of a panel of immunological urinary biomarkers as a liquid biopsy for the management of lupus nephritis. Plenary Abstr#1642 @RheumNow #ACR24 https://t.co/waSRVd7FV7
Antoni Chan MD (Prof) synovialjoints ( View Tweet)
@LennMcD @ACRheumDC
Current congress (118th) - very tight margins, paralyzed by the ‘24 elections. Now in lame duck
Many ACR policies made into bills - PA, step rx, copay accumulator, workforce, loan repayment, incr Rx transparency
Needs to be passed into law
@RheumNow #ACR24 https://t.co/1elEUiUAmh
Eric Dein ericdeinmd ( View Tweet)
@DrLauraCoates presented Sex differences in clinical presentations of PsA:
-Women present >polyarthritis, enthesitis and worse PROs which translates to ⬆️ DAPSAs in spite of less Rx progression.
-Men more oligoarthritis, axial involvement, higher skin disease.
#ACR24… https://t.co/iapZF0nZWX https://t.co/jZ79WfxZwh
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Adela Castro AdelaCastro222 ( View Tweet)