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Dr. Jack Cush reviews the journal reports and articles from this past week on RheumNow.com. The ACR (and Cush) address their new website designed to educate PCPs and APPs - what do you think?
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A large, propensity score-matched cohort study shows that metformin use in patients with pre-diabetes significantly lowers the risk of future gout.
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A single center study demonstrates that biologic treatment of psoriasis (PsO) significantly reduces the likelihood of psoriatic arthritis (PsA) development; suggesting a role for more aggressive treatment of PsO.
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The American College of Rheumatology recently launched Rheumatology for Primary Care, a new resource for primary care physicians (PCP) and advanced practice providers (APP) offering them expanded support and guid
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At the recent SPARTAN annual meeting in Cleveland, Dr. Jose Meade-Aguilar reported that amongst axial spondyloarthritis patients receiving nonsteroidal anti-inflammatory drugs, there was no difference in the risk for hypertension when comparing those on high vs. low dose NSAIDs.
Dr. John Cush
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Anakinra in COVID showed mixed (often negative) results. But this Turkish retrospective observational study comparing standard of care to IV anakinra in severe COVID pts. IV ANAK had less thromboembolic event (5% vs 12.3%, p = 0.038), better survival https://t.co/4webWJKEfB https://t.co/85GnCd6N8O
Dr. John Cush
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Forbes on the future of CAR-T cell therapy - A Gamechanger For Autoimmune Diseases. Innovation, costs, more trials and regulatory differences for autoimmune (vs cancer) patietns? https://t.co/1Yg40HPTzh https://t.co/NqCwEzmZ1g
Prof. Feynman
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There's a huge difference between knowing the name of something and knowing something.
We talk in fact-deficient, obfuscating generalities to cover up our lack of understanding.
NatRevRheumatol
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#JuneIssue | Relapsing polychondritis is challenging to diagnosis owing to overlapping symptoms with other conditions
Learn more about the clinical features and differential diagnoses in this #Review
https://t.co/iXl9rQ0ONS
Dr. John Cush
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Kaiser/California EHR study of #SLE pregnancies (2011-2020) - 657 pregnancies in 453 prs; The live birth rate = 74%, 23% w/ Spontaneous Ab, 2% ectopic/molar & <1% stillbirths. Variable outcomes by race & ethnicity, aPL status & nephritis history https://t.co/gvmYpTuFon https://t.co/9TeG8kfLmK
Dr. John Cush
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JAMA full read comprehensive review of 'Chronic Pruritus' affecting 22%, 1% of all out pt visits
- Dx algorithm
- Pathophys
- Rx options
- Alternative Rx
https://t.co/4sd2HqUX9Y https://t.co/FoVHFnfEPa
Dr. John Cush
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Do you have a rheumatology question or case for Dr. Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.
https://t.co/qvVEUoNYi5 https://t.co/duw6jg5xpp
Dr. John Cush
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Hypertension not associated with High NSAID Doses in AxSpA
At the SPARTAN meeting, Dr.Meade-Aguilar reported that amongst axSpA patients receiving NSAIDs, there was no diff in the risk for hypertension when comparing those on high vs. low dose NSAIDs.
https://t.co/UsRfobVHO7 https://t.co/fGj5yO53Yk
Dr. John Cush
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Save the date! We are covering #EULAR24! We'll be sharing recaps, videos, and more. https://t.co/vEQUZGAuJe
Dr. John Cush
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2 large 48-wk phase 3 trials (Be HEARD I/II) of Bimekizumab vs PBO in moderate-to-severe hidradenitis suppurativa shows BKZ to be safe & significantly effective (48% vs 29% & 52% vs 32%) vs PBO. https://t.co/xPXUd9vHyE https://t.co/uESOGYhAdw
Adam Grant
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Most leaders value loyalty. Great leaders put a higher premium on integrity.
Loyalty is allegiance to power. You're expected to show deference and follow orders.
Integrity is allegiance to principles. You're expected to challenge orders that violate your mission or values.
Dr. John Cush
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No Great Options for Treating VEXAS
For patients with the auto-inflammatory disease VEXAS, treatment decisions are unfortunately fraught with tradeoffs between effectiveness and risk of adverse effects, a French registry study showed.
https://t.co/tjCX1STnnD https://t.co/Bn40Nfxy9Y
Dr. John Cush
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The Window of Opportunity (5.24.2024)
Dr. Jack Cush reviews the journal reports and news from the past week on https://t.co/V10S4oVFsv. This week: blockbuster drugs, opioids in rheumatology and nontreatment of inflammatory arthritis?
https://t.co/zSjb2tKPWY
Dr. John Cush
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Preliminary results of ph IIB ORIGIN trial of placebo vs Atacicept (binds BAFF & APRIL)in 166 pts w/ IgA Nephropathy (Berger’s Dz) Gd-IgA1, hematuria, and UPCR (vs PBO) in the blinded 1st 36 weeks of the trial. https://t.co/tPhCrSaSTC https://t.co/6HqGFtb1IE
Dr. John Cush
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NHANES study of 2500 #RA pts, found a significant correlation between an inflammatory diet (meas by DII score) and inflammatory indices like systemic immune-inflamm Index (SII) & neutrophil-lymphocyte ratio (NLR) https://t.co/sWXZRrG6hV https://t.co/9IcLDF1Jlo
