Hypertension not associated with High NSAID Doses in AxSpA Save
At the recent SPARTAN annual meeting in Cleveland, Dr. Jose Meade-Aguilar reported that amongst axial spondyloarthritis (axSpA) patients receiving nonsteroidal anti-inflammatory drugs (NSAIDs), there was no difference in the risk for hypertension when comparing those on high vs. low dose NSAIDs.
Such findings may be important as axSpA patients have a higher risk for cardiovascular disease and hypertension and that NSAIDs are often employed as first line therapy.
Data was derived from the DESIR study of recent-onset axSpA in France. A total of 631 adult patients without HTN were enrolled and followed for 6 years.
Key takeaways:
- 11% developed hypertension;
- 39% of patients were high NSAID users;
- HTN was not associated with high dose NSAID use
These results may reflect the younger age of participants and earlier disease stage. The study was observational.
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