Skip to main content

Hypertension not associated with High NSAID Doses in AxSpA

  • Medscape

At the recent SPARTAN annual meeting in Cleveland, Dr. Jose Meade-Aguilar reported that amongst axial spondyloarthritis (axSpA) patients receiving nonsteroidal anti-inflammatory drugs (NSAIDs), there was no difference in the risk for hypertension when comparing those on high vs. low dose NSAIDs.

Such findings may be important as axSpA patients have a higher risk for cardiovascular disease and hypertension and that NSAIDs are often employed as first line therapy.

Data was derived from the DESIR study of recent-onset axSpA in France. A total of 631 adult patients without HTN were enrolled and followed for 6 years.

Key takeaways: 

  • 11% developed hypertension; 
  • 39% of patients were high NSAID users;
  • HTN was not associated with high dose NSAID use 

These results may reflect the younger age of participants and earlier disease stage. The study was observational.


If you are a health practitioner, you may to comment.

Due to the nature of these comment forums, only health practitioners are allowed to comment at this time.