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What's New in Lyme Disease

Jack Cush, MD

JAMA has published an overview of new considerations on Lyme disease, focusing on Diagnostics, Vaccines, and Prevention.

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POETYK PsA-1: Deucravacitinib in Biologic-Naïve PsA

Jack Cush, MD

POETYK PsA-1 trial tested the disease modifying efficacy of deucravacitinib, a tyrosine kinase 2 (TYK2) inhibitor, in psoriatic arthritis (PsA) patients and was shown to be superior vs to placebo for clinical responses, patient-reported outcomes, and structural damage inhibition in PsA.

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Mentshlichkeit* (8.7.2026)

Jack Cush, MD

Dr. Jack Cush reviews the news and recent journal reports on RheumNow.com.

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Air Pollution Increases RA Activity and Flares

MedPage Today

In this study from Korea, levels of small particulate matter correlated with increased RA disease activity and risk for disease flares.

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Top 20 Best Rheumatology Hospitals

Jack Cush, MD

U.S. News & World Report has published its Best Hospitals for 2026-2027, listing the best among many specialties, including rheumatology.  Each year U.S. News Best Hospitals ranked hospitals in the U.S.

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Keep HCQ Blood Levels Up to Avoid Cardiovascular Disease in Lupus

MedPage Today

People taking hydroxychloroquine (HCQ) for systemic lupus erythematosus (SLE) showed markedly increased risk for atherosclerotic cardiovascular disease when blood levels of the drug were low and when long-term adherence was poor, a prospective study showed.

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A Tribute to Daniel L. Kastner, MD, PhD (1951–2026)

Jack Cush, MD

The rheumatology, genetics and NIH communities mourn for Dr. Daniel L. Kastner, who died on July 28, 2026, in Bethesda, Maryland, at age 74. The following are declarations, tributes, and memories dedicated to this mensch of a man, titan of science, memorable mentor and humble physician.

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Arrhythmias in Autoimmune Rheumatic Disease

Jack Cush, MD

A new review in the Journal of Cardiovascular Development and Disease (Tamirisa et al) synthesizes how systemic lupus erythematosus, rheumatoid arthritis, and systemic sclerosis have an increased risk of arrhythmias and sudden cardiac death attributable to shared immune pathways.

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JAMA Review of Hip Fracture

Jack Cush, MD

The July 16th edition of JAMA reviews the highly prevalent problem of hip fractures - a major global health burden: 14.2 million occur worldwide annually (280,000 in the US), with global incidence higher in women (833.9/100,000) than men (510.0/100,000). Lifetime risk at age 50 is 22.9% for women, 10.7% for men. Mortality is substantial.

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JAMA Patient Education Page on: Therapeutic Use of Cannabis and Cannabinoids https://t.co/s6F7B9qLfr https://t.co/lpLGozJgvi

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Dr. John Cush RheumNow ( View Tweet)
NSAIDs reduces age-related macular degeneration. TriNetX study (2015-2024) looked at non-AMD pts & showed NSAID use (n 634794) had signif less AMD at 6 mos (HR 0.31), 1 yr (0.36), 3 yrs (0.42) & 5 yrs (0.48); w/ signif protective effect (HR 0.58), Same for ASA (0.72) & https://t.co/Cgxrz92Omt
Dr. John Cush RheumNow ( View Tweet)
Rethinking Treatment of EGPA Like MPA & GPA, the goals of EGPA are controlling initial organ damage and preventing relapse. But EGPA has the added challenge of chronic upper and lower respiratory tract involvement, allergic type 2 inflammations and risk of glucocorticoid https://t.co/KIVpyhsghg
Dr. John Cush RheumNow ( View Tweet)
“We may have all come on different ships; but we’re in the same boat now.” -Martin Luther King, Jr.

Dr. John Cush RheumNow ( View Tweet)

U Alberta Rheumatology study of GCAPS score in 62 new onset, suspected GCA referrals. GCA Dx in 39 pts excluded in 23. 50% had a High risk GCAPS (screening) score, 38% Intermediate & 13% had Low risk GCAPs. Intermediate or High risk GCAPS sensitivity 97%, specificity 30%, PPV 70% https://t.co/gKD1Je3QRH
Dr. John Cush RheumNow ( View Tweet)

True or False: In a 6-month RCT for refractory ITP, combining baricitinib with danazol achieved a durable response rate more than double that of danazol monotherapy. Take this week's RheumIQ quiz at https://t.co/yQn8cIT5Cw to see if you got it right! https://t.co/MJSw1gYUob

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Dr. John Cush RheumNow ( View Tweet)
Top 20 Best Rheumatology Hospitals U.S. News & World Report has published its Best Hospitals for 2026-2027, listing the best among many specialties, including rheumatology. At the top of the list are Johns Hopkins Hospital, Cleveland Clinic, Hospital for Special Surgery (HSS), https://t.co/IjGwcDQehq
Dr. John Cush RheumNow ( View Tweet)
A Tribute to Daniel L. Kastner, MD, PhD (1951–2026) The rheumatology, genetics and NIH communities mourn for Dr. Daniel L. Kastner, who died on July 28, 2026, in Bethesda, Maryland, at age 74. https://t.co/Qti4Nay6NX https://t.co/gjmY7G4XAc

Links:

Dr. John Cush RheumNow ( View Tweet)
U Alberta Rheumatology study of GCAPS score in 62 new onset, suspected GCA referrals. GCA Dx in 39 pts excluded in 23. 50% had a High risk GCAPS (screening) score, 38% Intermediate & 13% had Low risk GCAPs. Intermediate or High risk GCAPS sensitivity 97%, specificity 30%, PPV 70% https://t.co/HxHL60VAuO
Dr. John Cush RheumNow ( View Tweet)
💡 JAMA Insights: #SleepHealth and #obesity are linked, with insufficient sleep quantity and poor sleep quality associated with weight gain, less healthy diet, and incident obesity. https://t.co/SEj9dwNHiW https://t.co/JbPah4BwDr

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JAMA JAMA_current ( View Tweet)
Treatment goals in gout: aim for remission! Rheumatologists are used to the concept of disease remission as this is a treatment goal we use for many chronic rheumatic diseases in our clinical practice. Recently, G-CAN (the Gout and Crystal Arthritis Network), endorsed a https://t.co/PP2NBqvo7E
Dr. John Cush RheumNow ( View Tweet)
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