RheumNow Week in Review – 30 September 2016

Save

Three new FDA approvals, proteomics, cancer, infectious risk, nonadherence and disappointing clinical trial results covered in this RheumNow Week in Review.

No Difference in Infection Rates Among SLE Drugs

Save

Rates of serious infection and mortality among patients with systemic lupus erythematosus (SLE)  did not depend on the immunosuppressive drug regimen they were on, investigators reported.

Recognizing Arboviral Infections in Rheumatic Disease Patients.

Save

What does sex have to do with it? Although the Zika virus infection is known to be sexually transmitted, the same cannot be claimed for Dengue or Chikungunya.

New Shingles Vaccine Effective for up to Four Years

Save

In the current issue of the NEJM, a Herpes zoster subunit vaccine was reported to be highly effective in adults - specifically in 2 studies (ZOE50 and ZOE70) targeting adults over age 50 and over age 70 years. (Citation source: http://buff.ly/2cMng17)

Aspergillus Arthritis - A Rare Opportunistic Infection

Save

The International Osteoarticular Mycoses Consortitum has publist their review Aspergillus arthritis caused by invasive aspergillosis.

Their review identified 31 evaluable cases, 87% of whom were males and adults.

The RheumNow Week in Review – 9 September 2016

Save

Dr. Jack Cush reviews highlights from the past week on RheumNow.com, including IBD/TNFi and cancer risk, fracture nonunion, PMR worse in women, not treating asymptomatic hyperuricemia, and shingles followed by stroke.

Shingles Plus Autoimmune Disease Hikes Stroke Risk

Save

Patients with autoimmune inflammatory diseases who develop herpes zoster are at increased risk of stroke for the subsequent 3 months, with risks diminishing thereafter, analysis of Medicare data showed.

P. Gingivalis Antibodies Antedate Rheumatoid Arthritis Onset

Save

Periodontal disease, gingivitis and Porphyromonas gingivalis have been linked to the pathogenesis of rheumatoid arthritis (RA) and the production of anti-citrullinated protein antibodies (ACPA).

Is Biologic Safety Different in the Elderly?

Save

The factors that influence the safety of biologic therapy are numerous. Amongst them, increasing age is a potential risk factor, moreso if you also consider the polypharmacy, comorbidities and longer disease duration inherent in an elderly group of rheumatoid arthritis (RA) patients.

Risk of Sepsis or Death Lower with Biologics in Rheumatoid Arthritis

Save

Researchers from Germany have analyzed their large prospective rheumatoid arthritis (RA) registry to address whether being on biologic therapies leads to poorer outcomes - namely sepsis or death, following a serious infection (SIE).

RheumNow Week in Review – 5 August 2016

Save

Highlights from this week on RheumNow.com include:

1. Having #RA in addition to solid cancer (breast, lung, prostate, colon) increases mortality rates by 40-50% in elders https://t.co/aitjusmOai
2. The global market for rheumatoid arthritis therapies was $19.9 billion in 2015, expected to reach $21.3B by 2020 https://t.co/d2Sh5C8y9f
3. Half of doctors never heard of MACRA:Medicare Access & CHIP Reauthorization Act. Starts on Jan 1st! https://t.co/eYgWBWCw6y Blog:https://t.co/sRKZSOFyNV

And more!

Serious Infections are Not Increased in HIV Patients Treated with TNF Inhibitors

Save

Infections are a concern for many when using tumor necrosis factor-α inhibitor (TNFi) therapy to treat inflammatory disorders. Even moreso in those at higher risk.

Severe, Refractory Psoriasis in HIV-Positive Patients: Are TNF Inhibitors a Solution?

Save

Psoriasis and psoriatic arthritis are more prevalent, often more severe, and sometimes refractory to conventional treatments in HIV-positive patients, but clinicians are understandably concerned about moving on to immunosuppressive anti-tumor necrosis factor (TNF) agents when other treatments fai

Dinosaur Arthritis

Save

The recent edition of Science has an interesting article on the cause of death in a dinosaur - septic arthritis.

Palentologists have unearthed a 70 million year old duck-billed dinosaur near New Jersey and found that the arm bones were not quite right.  

RheumNow Week in Review - 29 July 2016

Save

Dr Jack Cush reviews this week's highlights from RheumNow.com.

SAPHO Syndrome Revisted

Save

SAPHO is an acronym that describes a constellation of findings (synovitis, acne, pustulosis, hyperostosis, and osteitis) that defines this rare syndrome. 

RheumNow Week in Review – 15 July 2016

Save

Dr. Jack Cush reviews highlights from this week's rheumatology news on RheumNow.com.

Gut Microbiome Shapes Risk and Response in Rheumatoid Arthritis

Save

In Genome Medicine, Mayo Clinic researchers investigated a cohort of rheumatoid arthritis (RA) patients, their relatives and a healthy control group analyzing the gut microbiome vial16S ribosomal DNA analysis of fecal samples.

10 Ways Rheumatoid Arthritis Could’ve Killed Glenn Frey

Save

I was truly stunned when it was announced that Glenn Frey, from the Eagles, had died as a result of complications from his rheumatoid arthritis, ulcerative colitis and pneumonia.