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Did you missed this past Tuesday Night Rheumatology? We have the playback available now. The PsA Expert panelists included: Dr. Dafna Gladman Dr. Joseph Merola, Dr. Peter Nash, Dr. Christopher Ritchlin, Dr. Jose Scher and Dr. Jack Cush. https://t.co/u5lt2uDoGK https://t.co/lOmN4OoGLi

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Dr. John Cush RheumNow ( View Tweet)
TNR,controversies,psa

TNR - Controversies in PsA

d Jack Cush, MD

Held on April 19, 2022, Tuesday Night Rheumatology: Controversies in PsA, featured a lively and informative panel discussion, moderated by Dr. Jack Cush.



The PsA Expert panelists included:

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child.guttate.psoriasis

Kids With Psoriasis Maintained with Long Term IL-17A Inhibitor

d MedPage Today

Pediatric patients with moderate-to-severe plaque psoriasis obtained significant improvement in disease status for as long as 2 years with the interleukin (IL)-17A inhibitor ixekizumab (Taltz), long-term follow-up from a randomized trial showed.

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Large metanalysis looks at Quality of Life outcomes w/ Therapies in #PSA 37 RCTs = 14.115 PsA pts ◾️ bDMARDs > PBO ◾️ bDMARDs = MTX (or Tofa) ◾️ bDMARDs + MTX > MTX https://t.co/6DDsVjcdcr https://t.co/ljb6AOH3UK

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Dr. John Cush RheumNow ( View Tweet)
QD Clinic - PsA Lessons from the Clinic Reasons why PsA patient can lose biologic efficacy and what to do about it QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022 https://t.co/Bxy1G68rU9 https://t.co/CLe9SHfRQJ

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Dr. John Cush RheumNow ( View Tweet)
How long does a good response last to a biologic? How and When to distinguish between flares and intercurrent illness. QD Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022 https://t.co/ZIWQysY5dd https://t.co/RZrS6FfUTV

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Dr. John Cush RheumNow ( View Tweet)
ICYMI: Review of 5 trials shows ixekizumab with higher rates of complete skin & nail clearance compared H2H against to etanercept, guselkumab, ustekinumab, and adalimumab (Data from IXORA-R, IXORA-S, UNCOVER-2, UNCOVER-3, & SPIRIT-H2H trials https://t.co/t5wrmE3nbK #PsA #PsAlways https://t.co/MQjgktOZWR

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Dr. John Cush RheumNow ( View Tweet)
RheumNow Podcast square

RheumNow Podcast – What You Do For & What You Do To the Patient (4.8.2022)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week and discusses the use of fibroscan in RA, steroid hip injections in OA and famous quotes from a famous cardiologist.

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CorEvitas Registry study of Axial #PsA pts showed 6 mos of bDMARD/tsDMARD resulted in modest, nonsignificant improvement axial outcomes,(irrespective HLA-B27 status), including ASDAS40, BASDAI50, & spinal pain. 31% of pts were B27+ https://t.co/9m9H7PwIIF #PsAlways https://t.co/dYk5GfIdez

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Dr. John Cush RheumNow ( View Tweet)
Network metaanalysis studied 46 RCTs biologics in #PsA. Some TNFi's numerically (not signif) better vsn interleukin inhib for ACR resps, but worse on PASI resps (IL-23, IL-17i had better PASI responses); No diff in enthesitis & dactylitis resps https://t.co/AvnoLRVi6C #PsAlways https://t.co/BSl9hVbIx6

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Dr. John Cush RheumNow ( View Tweet)
RheumNow Podcast square

PsA All the Way – Unmet Needs

d Jack Cush, MD

Throughout the month of April 2022, RheumNow is introducing a new approach to education and information sharing – a campaign devoted to a single disease. Our first campaign is entitled PsA All the Way: RheumNow will escalate awareness on this topic, its unmet needs, clarify advances and discuss key advances and modern disease management. We're featuring guest bloggers, hosting Tuesday Night Rheumatology, posting slides and videos, and much more dedicated to PsA.

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#PsA Biologic initiation was associated with a SMALL drop in NSAIDs (51.1 to 42.5%); glucocorticoids (57.4 to 46.9%) and opioids (38.1 to 33.8%) (Initial vs 12 mos later). Pain Rx use study in 5681 PsA, 2180 AS, & 34,047 RA pts #PsAlways https://t.co/wyrT9CVNq8 https://t.co/8vl7e2a63n

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Dr. John Cush RheumNow ( View Tweet)
Differences in Biologic Persistence in PsO and PsA Administrative claims analysis of biologic use in PsO and PsA in French health insurance databases shows that despite widespread biologic use, overall drug persistence was low for PsO and PsA biologics. https://t.co/PtrXu9xyFa https://t.co/RWciF4DqXj

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Dr. John Cush RheumNow ( View Tweet)
alopecia,areata,bald,hairloss

Baricitinib Efficacy in Alopecia Areata

d Jack Cush, MD

The NEJM has published the results of the BRAVE-AA1 and BRAVE-AA2 trials, demonstrating that baricitinib is effective at regrowing hair in alopecia areata (AA) patients, thus paving the way for future regulatory approval for this difficult to treat disorder. 

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CV,risk,MI,heart,cardiac

Stable Low Risk of Acute Coronary Syndrome in RA

d Jack Cush, MD

A Nordic multinational collaborative study examined the risk of acute coronary syndrome (ACS) in rheumatoid arthritis and found a less than 2 fold increased risk of ACS patients initiating biologic disease-modifying antirheumatic drugs (bDMARDs) with little risk variation with short-ter

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New download available. DMARD and Biologic Safety Prescribing https://t.co/zXE7HwgAYU https://t.co/pMQGPU6KCM

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Dr. John Cush RheumNow ( View Tweet)
Lit review of MDA5 antibody-positive clinically amyopathic dermatomyositis w/ ILD - shows limited data from 15 studies, 388 pts, 1 RCT: ? best survival with high-dose steroids + immunosuppressive (CTX or CyA/tacrolimus). Refractory dz Rx w/PLEX, Tofa, RTX https://t.co/LIl23O6x2Y https://t.co/qvISwpr7Mw

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Dr. John Cush RheumNow ( View Tweet)
Network meta-analysis reviewing PsO biologic treatments and QoL reviewed by Dr. K. Gordon at #RNL2022 @RheumNow https://t.co/BV8s1LJ7VX
Dr. Rachel Tate uptoTate ( View Tweet)
Do you use Otezla with biologics in PsA? #RNL2022 @RheumNow

Dr. Rachel Tate uptoTate ( View Tweet)

Completed Early RA prevention trials using agents like steroids, RTX, atorvastatin, abatacept No sig difference in steroids, atorvastatin RTX delayed onset but no overall diff Abatacept decreased RA progression at 1.5 years @RheumNow #RNL2022 https://t.co/v7WxI2P7r5
Robert B Chao, MD doctorRBC ( View Tweet)

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