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#Precisionmedicine is here but we’re not using it? A 23 molecular signature response classifier (MSRC) identified pts w RA unlikely to respond to #TNFi. no response was<ACR50 over 1yr. 175 w 26⬆️MSRC & 47 ⬆️⬆️MSRC. If ⬇️MSRC29%<ACR50 v 42&60%. ?cost Abst#1252 #ACR21 @RheumNow https://t.co/xdYyN0oXrh
Janet Pope Janetbirdope ( View Tweet)
Abst1100 #ACR2021 @RheumNow PAH in AOSD rare, mostly in polycyclic disease, associated w/flares (85%). overall survival 93% at 1 year and 74% at 3 years. PAH was severe at diagnosis: 2 (15%), 7 (54%) and 4 (31%) patients were in NYHA functional class II, III and IV, respectively. https://t.co/x20LooA2G7
Olga Petryna DrPetryna ( View Tweet)
Always thought⬆️health care access in Canada would lead to⬆️utilization of arthroplasty also rich-poor differences would be lower due to universal health access. Our study Canada Vs US and says otherwise!! Rich-poor differences are📈 greater in Canada! @rheumnow #abst1037 #ACR21 https://t.co/wKHXpsgSJn
Bella Mehta bella_mehta ( View Tweet)
While outcomes didn't worsen, de novo PsO can occur at any time point in axSpA (results per 6 year, DESIR cohort study.) Regular follow ups are key to monitoring. Abs 1311 #ACR21 #RheumNow #ACRbest @RheumNow https://t.co/X1bot5UJ6Q https://t.co/qfbDhCT9q5
Dr. Rachel Tate uptoTate ( View Tweet)
Well, this just got fun.
Let's follow this, blow by blow in this thread.
@US_FDA session #ACR21 @RheumNow https://t.co/3GCRfsINgn
David Liew drdavidliew ( View Tweet)
Abstr 1317
Impact of Memory in #axSpA
Compared to healthy controls, patients with #axSpA performed significantly worse on Memory and Attention Test (MAT) specifically in working memory and selective attention
#ACR21 @RheumNow https://t.co/PJS2QroKOS
Akhil Sood MD AkhilSoodMD ( View Tweet)
Why do pts get #RheumatoidArthritis & also #psoriatic in same jts? Also #psoriasis recurs in same spots. Memory cells, altered permeability of cell membranes? Dunno but neat study shows early RA jt involvement likes to recur in same jts. But can spread! @RheumNow #ACR21 abst#1216 https://t.co/qCORzfhjqH
Janet Pope Janetbirdope ( View Tweet)
MSK Ultrasound demonstrated continued improvement of synovitis and enthesitis in PsA pts on secukinumab.
⭐️continued improvement of GLOESS (synovitis) and OMERACT enthesitis score at 52 weeks
Abs#1360
#ACR21
@RheumNow
https://t.co/ISVZrXkEiI https://t.co/dXlfi3R962
Robert B Chao, MD doctorRBC ( View Tweet)
Routine evaluation of MRE and MRI in Crohn's Disease could be a way to detect axSpa. 25% of 48 CD patients had abnormal SI joint finding, majority asymptomatic,
female, and had stricturing or penetrating CD @RheumNow #ACR21 Abst#1306 #ACRBest https://t.co/MYMV3UDGck https://t.co/p9fov02OdH
Dr. Antoni Chan synovialjoints ( View Tweet)
What matters for PsA pts & MDs?
In this study, pts and MDs in consensus w/#arthritis dse activity, fatigue & pain as impt aspects of PsA care; but disparities still exist👇
MDs-clinical
Pts-access to care, sleep
Communication is🔑➡shared decision making
@RheumNow #ACR21 abs1165 https://t.co/Zd4r47OMGx
sheila RHEUMarampa ( View Tweet)
A clever hack for those who have difficulty with public speaking! I would add breathe to this list! Janet Zeide presents "RHEUM" during The Gift of Gab at #ACR21 @RheumNow https://t.co/fjAFZDiao5
Dr. Rachel Tate uptoTate ( View Tweet)
A retrospective cohort study demonstrates a statistically and clinically significant lower risk for developing PsA among patients with psoriasis that receive biologic medications
Abst #1355 #ACR21 @RheumNow https://t.co/OK20VKO82f
swethaann23 swethaann23 ( View Tweet)
@SattuiSEMD on frailty in PMR. High prevalence frailty (12-17%) and pre-frailty (54-59%). Frailty associated worse HRQoL. Abstr#1392 #ACR21 @RheumNow https://t.co/Y2evVHrrTa
Richard Conway RichardPAConway ( View Tweet)
#ACR21 Opening Day Recap: Drs. Cush, Dao ( @KDAO2011) , Tate ( @uptotate) and Reyes ( @RHEUMarampa )
https://t.co/v0DH4jY84v https://t.co/oflVOkzSie
Links:
Dr. John Cush RheumNow ( View Tweet)
"If you follow this advice👇, you will be the best speaker in the RHEUM!"
😉😊🤓
@RheumNow #ACR21 https://t.co/y2IYMFJChE
sheila RHEUMarampa ( View Tweet)
Efficacy to the COVID-19 vaccine is based on both humoral (antibody) and cellular responses. Rituximab impairs B-cell response but not T-cell response to COVID-19 vaccine in auto-immune diseases @RheumNow #ACR21 8M101 Mariette X https://t.co/RoFTC6VpCt
Dr. Antoni Chan synovialjoints ( View Tweet)
Prevalence of abnormal SI joint findings on MRE and MRI is 25% in Crohn's pts. Majority didn't report back pain, were female, and had intestinal complications of CD. Abs 1306 #ACR21 #RheumNow @RheumNow https://t.co/LOGoxAfrQi https://t.co/qAKC8GCLno
Dr. Rachel Tate uptoTate ( View Tweet)
Abst1005 #ACR21 #ACRBest @RheumNow study identifies monocyte-derived DC population characterized as CD209+/CD14+ DC in the synovium of RA and PsA patients sensitive to JAK/STAT, but not TNF inhibition.
Olga Petryna DrPetryna ( View Tweet)
VACOLUP study: COVID19 vacc, 1189 SLE pts
👉No sig. diff based on gender, age, nor type of vax
👉3.2% pts w/SLE flare
👉Flares mainly fatigue and MSK symptoms (SLE flare or side-effect of the vac?)
https://t.co/w5dYsLkk5D
#ACR21 Abst#1421 @RheumNow #ACRBest
Pedro Castillo _Castillo_Pedro ( View Tweet)
Dr Keen presenting on GCA admitted to hospital. Propensity score matched to non-GCA population. Increased all cause mortality compared to general population in Western Australia (aHR 1.13). Most pronounced in early years after diagnosis. Abstr#1393 #ACR21 @RheumNow https://t.co/laW8mxp6uq
Richard Conway RichardPAConway ( View Tweet)