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A survey of 317 carers and clinicians focused on psoriatic arthritis has set an agenda of the top 10 research questions for psoriatic arthritis (PsA).
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The first large multi-ancestry genetics study of osteoarthritis (OA) has found 10 novel OA-associated genetic loci, and results showed some of the OA-associated regions are robustly found in every population ancestry studied.
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A recent randomised clinical trial suggests immunomodulators reduce arterial inflammation, and thereby cardiovascular (CV) risk, but shows no significant benefit to TNF inhibitors over triple therapy in patients with rheumatoid arthritis (RA).
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The biosimilar landscape will change dramatically in 2023, following the successful rollouts in other countries in Europe.
Dr. John Cush
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Comorbidities in Ankylosing Spondylitis
Dr. Akhil Sood ( @AkhilSoodMD) discusses Abstract 1609 at #ACR22 Convergence.
https://t.co/tX0gP3mYmW https://t.co/PYLpoczz08
Dr. John Cush
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Vaccines Work!
Dr. Eric Dein ( @ericdeinmd) and Dr. Caoilfhionn Connolly discuss abstracts 2275 & 0797 at #ACR22 Convergence.
https://t.co/xXcs5yQPSi https://t.co/1C4Cj9Ykei
Dr. John Cush
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Systematic review of MSK findings in patients with acute lymphoblastic leukemia finds 29 pts with peripheral arthritis (7), axial manifestations (17), and osteolytic lesions (21 pts) & Vertebral Fx (4) Hypercalcemia in 9 cases. https://t.co/DhCMMlMs7f https://t.co/HjjL4aF22a
Dr. John Cush
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Comparison of 227 Systemic Sclerosis pts w/ & without ILD shows SSc-ILD to have more muscle Dz [OR 2.55], LVDD [OR 2.36], PAH [OR 9.13], dcSSc [OR 2.86], PLR [OR 1.005], elevated KL-6 [OR 2.03], and anti-Scl-70 [OR 3.1]. https://t.co/Pzx9N5rPcF https://t.co/F8mBQ1u5iL
Dr. John Cush
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Fat and bone are never alone: osteoporotic fracture in RA
Dr. David Liew ( @drdavidliew) discusses Abstract 889 at #ACR22. Abstract 889: Serum Adipokines Predict Incident Osteoporotic Fracture in Patients with Rheumatoid Arthritis
https://t.co/jSFmOiQb6N https://t.co/JTXugoxofP
Dr. John Cush
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Gender Differences in axSpA
In abstract 1614, Dr. Poddubnyy presents the results of the PROOF study which assessed the probability of achieving inactive disease or low disease activity among males and females who were recently diagnosed with axSpA.
https://t.co/DL2TDgXJnG https://t.co/XSQxWWnQgD
Dr. John Cush
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Lupus Linked With Greater Risk of Cardiovascular Complications of Childbirth
Pregnant women with SLE were more prone to cardiovascular complications during delivery, and their risk seems to have increased over the past 15 years, according to data.
https://t.co/mRUOVrKbt2 https://t.co/m18DWxSV20
Dr. John Cush
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Retrospective study of US National Inpatient Sample data 2015-2019 looked at 60,360 gout admissions, roughly 1/4 had Arrhythmias (mostly older pts; AFib (88%), atr flutter (6.2%), VTach (3.2%). Gout-arrhythmia pts had more deaths (adj OR 2.06) https://t.co/L1WEsybI7h https://t.co/xwAfFVJOuk
Dr. John Cush
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In pts undergoing hip or knee arthroplasty for OA, aspirin (3.45%) compared with enoxaparin (1.82%) resulted in a significantly higher rate of symptomatic VTE within 90 days, defined as below- or above-knee DVT or pulmonary embolism https://t.co/7hgLbynNx6 https://t.co/HMc4UbMcdy
Dr. John Cush
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RA-ILD takes centre stage
Greg McDermott presented abstract 2248 on the prevalence and mortality of subpleural interstitial lung abnormalities (ILA) in RA and non-RA comparators.
https://t.co/zrg7IEhBfg https://t.co/dKACCzr4CZ
Dr. John Cush
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More Than a Conference:Life’s Lessons
By: @KDAO2011
This is my 20th year attending the ACR meeting; despite my virtual attendance, I was still able to connect w/people. I reflected on my experiences w/ the conference and wanted to share my life lessons.
https… https://t.co/9gBbaYBujc
Dr. John Cush
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MTX side effects more prominent in PsA than RA pts. Study of 240 PsA & 86108 RA pts starting either MTX or TNFi. TNFi AE same betw PsA & RA, but MTX adverse greater in PsA (44.8% vs. 29.4%), especially N/V, abdominal pain, depression, tinnitus https://t.co/0QBc6sb900 https://t.co/FZibAeFDBx
Dr. John Cush
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Sleep Quality & PsA
Abstract #0387 presented at #ACR22 attempted to shed light in this important quality of life determinant. 247 adult PsA patients were included in this study and their sleep quality was measured using the PSQI questionnaire.
https://t.co/lLTnrh2yxG https://t.co/9ViEnEFE6c
Dr. John Cush
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Humira biosimilars became available in EU 10/18; and will soon be available in the USA w/ Amjevita (Amgen) available Jan 2023 & 6 others (Pfizer, BI, Samsung, Coherus, Sandoz, Biocon) after July 2023. https://t.co/LH3MpT0o9O https://t.co/VeCbcdq5Ie
Dr. John Cush
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Methotrexate + pegloticase increases response rates in gout
Patients with refractory gout and those with high burden of tophi have only few options when it comes to uric acid lowering agents.
https://t.co/8cqsAXuzIB https://t.co/OSpf5ehiCm
Dr. John Cush
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Best of ACR Day Two in PSA
https://t.co/FXGCPaTGX6 https://t.co/WICtjVICC2
