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When to Stop Biologics in Systemic JIA?

d Jack Cush, MD

Systemic onset juvenile idiopathic arthritis (sJIA) is a dramatic onset inflammatory condition marked by spiking fevers, intermittent rash, polyarthritis and a host of other hyperinflammatory manifestations.

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T2T Debate - A Prologue with Dr. Marty Bergman

d Jack Cush, MD

Drs. Jack Cush and Martin Bergman review the topic of treat-to-target (T2T) management in rheumatology.



Both will debate the pro's and con's of the T2T strategy at the upcoming RWCS meeting on Feb. 17, 2022.

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Feet, foot

Pre-clinical RA: starting off the wrong foot

d Aurelie Najm, MD, PhD

Patients with clinically suspect arthralgia can represent a challenge for clinicians, in a sense that there are not yet reliable markers to predict evolution to clinical RA nor enough evidence to support routine prescription of conventional synthetic DMARDS or biologic treatments in this setting.

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Genes and Obesity Tied to Higher Gout Risk in Women

d Jack Cush, MD

Excess adiposity and genetic predisposition both contributed to risk of gout among U.S. women, with the risks being highest when both factors are present, a large prospective study found.

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NYC Hosp for Special Surgery is the 1st to use a "smart" knee arthroplasty - TKR with a smart sensor capable of monitoring steps, speed, range of motion & other knee functions fed back to the orthopedist = called Persona IQ, FDA authorized https://t.co/QR49JC7oCz

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Pre-clinical RA: starting off the wrong foot https://t.co/LA2dLaAM6C https://t.co/lgKFY0zDeq

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Dr. John Cush RheumNow ( View Tweet)
Genes and Obesity Tied to Higher Gout Risk in Women Excess adiposity and genetic predisposition both contributed to risk of gout among U.S. women, with the risks being highest when both factors are present, a large prospective study found. https://t.co/vLR8GJC9qf https://t.co/6Scc5c0dUU

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Fibromyalgia pts are prone to suicidal ideation (29.6%; OR 9.1), attempts (5.7%; OR 3.1), & events (OR 1.38), but significance lost when correcting for psych illness. Risk assoc w/ work, dz severity, obesity, addiction, chronic pain & co-morbidities. https://t.co/jjiZ5iZBjP https://t.co/cuCsKKcOj7

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ICYMI: TNF inhibitors and radiographic progression in axSpA A remaining challenge for clinicians is the ability to delay, if not completely stop, structural progression in patients with (ax-Spa, whether they are diagnosed with -axSpa or nr-axSpA disease. https://t.co/H0Fr54PwOP https://t.co/tFZJUr1j4B

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ICYMI:CDC and the ICD-10 Coordination and Maintenance Committee has assigned a diagnostic code for non-radiographic axial spondyloarthritis (nr-axSpA) == M45.A

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FDA Puts Boxed Warnings on JAK Inhibitors Based on the safety review of tofacitinib in Pfizer's Oral Surveillance study, the FDA has formalized the recommendation that patients should be started on a TNF inhibitor (TNFi) before trying a JAK inhibitor. https://t.co/bXZ4Yedyyv https://t.co/tsvHOtIEK0

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ICYMI: Risks associated with mortality in VEXAS https://t.co/mpAc5shaMq https://t.co/FdOQcfwusp

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ICYMI: Zoom Fatigue is real. Study shows fatigue is from being on-cam that triggers self-presentation - the needs to monitor how you look to others; more common in women. Suggest: reduce monitor/image size & Turn off Self view (avoid self evaluation) https://t.co/vS8tJv9Kpd https://t.co/F7mHdYgOXy

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New podcast up! Drs. Jack Cush and Martin Bergman review the topic of treat-to-target (T2T) management in rheumatology. Both will debate the pro's and con's of the T2T strategy at the upcoming RWCS meeting on Feb. 17, 2022. https://t.co/oe6hsAq2KG https://t.co/1sbTmd9cnV

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Download Available! The Scary Side of Steroid. Log in and download today. https://t.co/sYVWGTVHgx https://t.co/NIbi49SJEo

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AURORA 2 results were presented at #ACR21 - a continuation study of voclosporin in 116 active Lupus Nephritis pts randomized to either PBO or voclosporin. After 36 mos the VOC group had stable GFR and reduction in proteinuria https://t.co/O7G1dCIzbP

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ASK CUSH ANYTHING! Have a Rheumatology question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. https://t.co/tl3Nkxdv0B https://t.co/WwxgWGuVcC

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Check out our blog by Dr. Kathryn Dao ( @KDAO2011) on "Redefining Aging." https://t.co/GbE77GTa0y https://t.co/e2GYETqsUR

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CBD and Opioids in PsA : Dr. Eric Ruderman ( @JointMD) reviews abstract #1456 and #1777 presented at the ACR21 annual meeting. https://t.co/ZATSfzqj51 https://t.co/dhFwgS9b6J

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Should we start considering therapeutic drug monitoring when prescribing TNFi for treatment of our rheumatologic conditions? https://t.co/RbOlrnW54O https://t.co/iDlqwv32zs

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