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Passive Smoke Exposure and Rheumatoid Risk
A current report in Arthritis & Rheumatology examined the Nurses Health Study II data set and shows that parental smoking, and passive exposure to children, can later lead to an increased risk of adult-onset incident seropositive rheumatoid arthritis (RA).
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Most recent numbers from the CDC - The agency said 202,041,893 people had received at least one dose while 171,367,657 people are fully vaccinated as of Tuesday. https://t.co/3rp7QMt84y
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Safety study of 97 AAV (72 GPA, 25 MPA) pts Rx with Rituxan, median 8 infusions, followed median 3.9 yrs (0.05–4.32). Serious Risks (per 100 Pt-Yrs): serious infections 7.11, cardiac events 5.0, & vascular events 2.37. No deaths related to RTX. https://t.co/WLMQoq79gd
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Psoriasis Prevalence in adults in the United States is 3.0%, indicating that more than 7.5 million adults 20 years or older have psoriasis. Most common in non-Hispanic White individuals; prevalence has not significantly changed since 2003. https://t.co/3yrlPu1GGi
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New download available!
Cytokine Storm Overview
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Dr. John Cush RheumNow ( View Tweet)
A current report in Arthritis & Rheumatology examined the Nurses Health Study II data set and shows that parental smoking and passive exposure to children, can later lead to an increased risk of adult-onset incident seropositive rheumatoid arthritis (RA).
https://t.co/szl5L7DGJG https://t.co/yxoEquyLjP
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Dr. John Cush RheumNow ( View Tweet)
Rheums--have a question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.
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European Commission has approved tofacitinib (Xeljanz) to treat active polyarticular juvenile idiopathic arthritis & juvenile psoriatic arthritis (PsA) > 2yrs old, not responding to DMARDs (as tablet & new oral solution (weight-based dosing) https://t.co/FyqZI0qsYa
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Dr. John Cush RheumNow ( View Tweet)
Watch Now:
Using Vitamin D in RA
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Dr. John Cush RheumNow ( View Tweet)
Comprehensive, full read overview of (European EADV) S2k guideline: Diagnosis and management of cutaneous lupus erythematosus – Part 1 (classification, Dx, activity) & Part 2 (Treatment) https://t.co/puBCr8VO1I https://t.co/rZKDEsvDzr
Dr. John Cush RheumNow ( View Tweet)
Breakthrough infections: As of Aug. 9, almost 74% of the 8,054 vaccinated people that were hospitalized with COVID-19 were above the age of 65, according to the U.S. Centers for Disease Control and Prevention. ~20% of those cases ended in deaths https://t.co/jaSmKv5pPS
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Dr. John Cush RheumNow ( View Tweet)
Oligoarticular vs. Polyarticular Psoriatic Arthritis
https://t.co/lQVNdmWgMc https://t.co/Kswfkbp5nC
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Dr. John Cush RheumNow ( View Tweet)
The CDC has reported that mRNA vaccine effectiveness against COVID-19–associated hospitalizations was sustained over 24 weeks; but there is evidence of waning protection amongst the immunosuppressed.
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The interleukin-6 inhibitor, tocilizumab (TCZ), was studied in a cohort of difficult systemic sclerosis (SSc) and was shown to be effective in refractory joint and skin disease with good long-term retention rates and disease stabilization. https://t.co/XkJDVwJLwb
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ICYMI:
Belimumab in Pregnancy? a study of 13 pregnancies in 13 pts, mean age 38 yrs.. There were 11 live births, 1 case omphalitis (recovered w Abx) . No fetal anomalies found. 6 pts (46%) w/ Hx of recurrent pregnancy loss, four had live births on BEL https://t.co/FJJhepa25M
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#RA & Driving studied w/ installed auto sensor-based instrumentation - 23 controls compared to 33 RA pts (1292 driving hrs): shows RA & worsening Dz severity assoc w/ poor vehicle control; Braking/accelerating & steering variability liked to CDAI levels. https://t.co/umXGAbuicz https://t.co/EYxVVkzxR8
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Dr. John Cush RheumNow ( View Tweet)
Are you holding Otezla, SSZ, or leflunomide post vaccination? @RheumNow @LCalabreseDO @CCalabreseDO @DrDavidKarp @RADoctor @JointMD @JYazdanyMD
k dao KDAO2011 ( View Tweet)
@AngusWorthing @rheumecraig @ravenswoodrheum @JointMD @RheumNow @LCalabreseDO @CCalabreseDO @DrDavidKarp @RADoctor @JYazdanyMD @alhkim Do we have data that NSAIDS and acetaminophen alter antibody response? I would rather pts take acetaminophen or ibuprofen post-vax than prednisone.
k dao KDAO2011 ( View Tweet)
New podcast available for download wherever you get your podcasts! We review the big stories on RheumNow this week.
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Dr. John Cush RheumNow ( View Tweet)