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RheumNow Podcast – As Good As I Ever Was (7.2.2021)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

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Gender Trends in Rheumatology

d Jack Cush, MD

A study of rheumatologists in Ontario, Canada has shown an increasing percentage of women in rheumatology; unfortunately they have lower salaries but see fewer patients than do their older, male colleagues.

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Neuropsychiatric Events Common in Lupus

d Jack Cush, MD

Neuropsychiatric (NP-SLE) or CNS lupus events range from mild to severe; several recent studies have noted that NPS lupus is common and should be screened for.

A metanalysis of the literature finds 22 studies wherein the mean frequency of NPSLE ranged from 10.6% to 96.4%. When researchers with the Swiss SLE cohort study looked at their population, NPSLE was found in 28.1%. This included cerebrovascular insults, seizures and psychosis.

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New ACR Rheumatoid Arthritis Guideline: Emphasis on Methotrexate

d MedPage Today

The American College of Rheumatology (ACR) has issued new guidelines on the treatment of rheumatoid arthritis, addressing questions about initial treatment with methotrexate and minimizing reliance on glucocorticoids.

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A study of rheumatologists in Ontario, Canada has shown an increasing percentage of women in rheumatology; unfortunately they have lower salaries but see fewer patients than do their older, male colleagues. Read more: https://t.co/JM0345p8f1 https://t.co/y95LQ6lX5i

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Download this week’s podcast titled “Good as I Ever Was”. You can find us on SoundCloud and wherever you download your podcasts. https://t.co/hVMf8X5Dx3 https://t.co/uUDCXzO2eU

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New ACR Rheumatoid Arthritis Guideline: Emphasis on Methotrexate https://t.co/J9wmcZr17D

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How risky are family gatherings, birthday parties and informal social gatherings? Read more… https://t.co/jyGHakndUt https://t.co/7eps0EFVWy

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Brand new RheumNow podcast up titled “As Good As I Ever Was” Download now. https://t.co/hVMf8X5Dx3 https://t.co/2R2kq7dwp5 https://t.co/5mahn4D46M

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Therapeutic Drug Monitoring for Infliximab: Might it Actually Work? https://t.co/Onl6cijKbb https://t.co/jnwx4ZZvhz

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Ten Things to Tell Patients About Diet and Rheumatic Disease https://t.co/DpBAJwCJCY https://t.co/AVlgHfdP08

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With the expansion of knowledge regarding the safety of newer agents in pregnancy comes the PreCARA study showing that when pregnancy is planned and patients with RA are treated with a modified T2T approach, superior outcomes can be anticipated. Read on: https://t.co/sV5hJRzPJW https://t.co/ADppVd3CmZ

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The ACR has released an updated position statement on patient safety and site of service for biological. https://t.co/NONozoIIq6 https://t.co/CSbSuXBb8n

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Health care utilization by knee OA pts varies. In nearly 1 million Knee OA (Medicare), 33% ended up with TKR. TKR/arthroplasty assoc w/ more clinic visits; PT, specialist care & intraarticular Rx assoc. w/ less TKR. TKR range 26% to 42% by region https://t.co/d1EQTTie8X

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CDC: as of 5/15/2021; the rates of flu test positivity was 0.051-0.18% for the 2020-21 flu season - compared to usual rate of 10%-19% before COVID. Actual influenza hospitalizations dropped from 44.2 to 0.8/100 000 population https://t.co/N8b1sQWWIh

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Higher rate of Parkinsonism in Osteoarthritis? Taiwan Health Insurance claims analysis of 33,360 OA pts (age 50-64 yrs) vs age matched non-OA - found incr risk of Parkinsons in OA pts (aHR=1.41), esp in knee or hip OA (aHR 1.55) group. https://t.co/SHudF5NnwH

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Stroke risk is increased in arthritis (RR 1.36, 95% CI: 1.27–1.46); esp for RA (RR 1.38), AS (RR 1.49), PsA (1.33) & gout (1.40); but NOT osteoarthritis (RR=1.03). Apparently Inflammation drives this risk. https://t.co/Snb6OrtZJH

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Global metanalysis of 67 studies of T2T in gout shows only 34% on ULT achieve a serum urate target. Thus only a minority of gout receive T2T care worldwide. Thos on ULT, have low rates of continuous Rx, SUA testing, & achieving SUA target https://t.co/zpBRhRaek5

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BRAVE-AA1 - a Phase 2 trial of 110 pts w/ Alopecia areata Rx w/ either PBO or baricitinib (1, 2, 4 mg); showed significantly greater improvement with Bari 2-mg (33.3%, P = .016) and 4-mg (51.9%, P = .001) versus placebo (3.6%). https://t.co/tzDeb4l60H

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Retrospective study of 258 IBD patients, 17% had MRI sacroiliitis (73% w/ bone marrow edema. Sacroiliitis was significantly associated w/ Female gender, back pain, and later age of CD diagnosis. >two-thirds of these pts never seen a rheumatologist. https://t.co/HYhAU6aRIf

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