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Methotrexate Impairs COVID Vax Response

d MedPage Today

One-third of patients with immune-mediated inflammatory diseases being treated with methotrexate showed attenuated responses to the COVID-19 vaccine, researchers reported.

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Efficacy of 6 Weeks Antibiotics with Prosthetic Joint Infections

d Jack Cush, MD

The NEJM has published the results of a French multicenter study showing that prosthetic joint infections can be successfully managed with 6 weeks of antibiotic therapy; this was noninferior and had better outcomes compared to 12 weeks of antibiotic therapy.

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EULAR Guidelines on Intraarticular Therapy

d Jack Cush, MD

EULAR has published evidence-based recommendations on the use of intra-articular therapies (IAT) based on the literature review and recommendations of a multidisciplinary international task force. These IAT recommendations apply to adult patients with peripheral arthropathies.

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Triple DMARD Therapy Bested by Biologics in Swedish Registry

d Jack Cush, MD

The Swedish Register compared outcomes of 1502 rheumatoid arthritis (RA) patients initiating either biologics plus methotrexate (MTX) or triple therapy (MTX plus sulfasalazine plus hydroxychloroquine/chloroquine) and showed similar rates of sustained remission.

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CV Risk Decreased with Certain DMARDs in Rheumatoid Arthritis

d Jack Cush, MD

A large prospective cohort study examined the comparative risks of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) and found that, methotrexate (MTX), abatacept (ABA) and TNF inhibitor (TNFi) use were associated with a decreased risk of CV events. 

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Tocilizumab Augmented Efficacy in COVID-19 Pneumonia with High CRP

d Jack Cush, MD

JAMA Internal Medicine report an analysis of recent and composite trial data suggesting that tocilizumab (TCZ) therapy in COVID-19–associated pneumonia patients with high CRP levels is likely to be effective.

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Congress Slams AbbVie Over Price Hikes, 'Frivolous' Patents

d MedPage Today

House lawmakers on both sides of the aisle pummeled AbbVie CEO Richard Gonzalez for raising the price of two widely used drugs and for the company's "legally questionable" tactics to head off competition from biosimilars, despite pulling in healthy profits.

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Virtual DDW meeting this wk reports claims data comparing IBD to IBD with RA - IBD alone vs IBD w/ RA dx w/ more depression (21% vs 84%), anxiety (20% vs 47%). IBD w/ RA had more depression (OR 7.2); anxiety (OR, 1.25;) or both (OR, 2.3) https://t.co/B78xcJw584

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News Feature: CV Risk Decreased with Certain DMARDs in Rheumatoid Arthritis A large prospective cohort study examined the comparative risks of CVD in patients with RA and found that, MTX, ABA & TNFi use were associated w/ a decreased risk of CV events. https://t.co/uQbtB76Hgy https://t.co/ftc5ys9C58

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Mark your calendars--we'll be covering EULAR 2021 from June 3 through June 8. Over coverage will include new articles, videos, polls and more. https://t.co/LksbsK2TW2
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Interesting report of 27 pts w/ Jo-1 anti-synthetase syndrome shows that only 4 had classic triad at presentation. 7 patients presented with polyarthritis, 6/7 initially Dx as #RA, Time gap from RA to antisynthetase dx was 3 to 20 years. https://t.co/IMgk3VTr0c

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Dr. Samir V. Parikh from the #SLEEducatorsNetwork discusses the major treatment goals for lupus nephritis and the broader needs of the patient in this program- Defining Treatment Goals for Lupus Nephritis. Sponsored by GSK US Medical Affairs https://t.co/f2Y707YDJr https://t.co/lsYDVFWSCS

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Good Free 2 part series on Juvenile Fibromyalgia: a chronic diffuse musculoskeletal aching and pain syndrome that may be hard to distinguish from complex regional pain syndrome (CRPS) (ALWAYS CHECK FOR HYPERMOBILITY in Kids) https://t.co/EPmmGVNW63 https://t.co/aP6QHT7tiM

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Preliminary results from 600 pt SAVE-MORE trial in severe COVID, anakinra + standard-of-care was 55% better than SOC in preventing death or respiratory failure; and improving Hosp Discharge by 4 days. Anakinra Rx 100mg/day up to 10 days https://t.co/vbpUMQjC1o

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Popular Read: Little Effect with Multimodal Treatment of CMC1 Osteoarthritis https://t.co/6SnJYOK6nu https://t.co/ldTQRujshq

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RNL 2021 - Future Therapies in RA: Dr. Roy Fleischmann https://t.co/icnRaUHo5k

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Meet the #SLEEducatorsNetwork in this disease education series where leading rheumatologists and nephrologists share their perspectives on lupus nephritis. Sponsored by GSK US Medical Affairs https://t.co/H9BqP9bW4i https://t.co/VzS95UBJeo

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News: Factors Associated with COVID-19 Deaths in Rheumatic Patients https://t.co/FzsINtpZEz https://t.co/QzuLZRKaZy

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Levamisole, an anti-helminthic vet drug, is used as a colorless, odorless, adulterant to narcotics, cocaine, fentanyl, etc. Levamisole also causes ANCA+ Vasculitis (small to medium vessels), palpable purpura, agranulocytosis https://t.co/BKoDo2iemJ https://t.co/bSl0eYn0yO

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RheumNow Live is now available for all--check out any panels you may have missed. https://t.co/jaisVc2kGt https://t.co/Z9m7V96g1g

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