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Long COVID and Rheumatic Disease

Akhil Sood, MD

The COVID-19 pandemic has had a significant impact worldwide particularly among those who are immunocompromised. Numerous studies have highlighted the increased risk of acute SARS-CoV-2 infection among patients with rheumatic diseases (RD).

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creaky,joints

Creaky Joints Presentations at ACR Convergence 2022

Jack Cush, MD

The patient advocacy organization CreakyJoints will present 13 scientific posters at this year's ACR Convergence 2022 and 8 posters as part of the patient perspectives track. Below is a sampling of these scientific posters. 

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Women with Rheumatic Disease (11.4.2022)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com.  New regulatory decisions about JAK inhibitors and why do women with rheumatic diseases have unfair outcomes?

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undifferentiated,arthritis,early,RA

Undiagnosed RA During the Pandemic

EurekAlert!

The number of new diagnoses of rheumatoid arthritis fell by 20% in the first year of the COVID-19 pandemic, new research suggests.

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Infections & Lupus (10.28.2022)

Jack Cush, MD

Dr. Jack Cush discusses the news and journal reports from the past week on RheumNow. This week more lupus nephritis, more drug induced lupus and more lupus infections that may kill. 

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ACR Award Winners (10.21.2022)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. Highlighted discussion of implantable stimulators, urine proteomics and gut-immune responses to Prevotella in RA.

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covid.corona

Vaccination Cut Long COVID Risk for Rheum Patients

MedPage Today

Patients with rheumatologic conditions who developed breakthrough COVID-19 infection after vaccination were less likely to suffer long-term symptoms than unvaccinated but otherwise similar patients, researchers said.

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#ACR22 Year in Review. Dr Langford summarised significant progress attained in 2022 in combating #COVID and protect our immunosuppressed patients @RheumNow https://t.co/lZSDRj3bkm
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Study showing Evusheld can protect our patients who are immunosuppressed; it saved alot of live. One of Dr. C Langford's pick for #YearinReview @rheumnow #ACR22 https://t.co/6ekWvA6Ruw

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TheDaoIndex KDAO2011 ( View Tweet)

Was delighted to be a (very) small part of the fantastic work by the covid GRA getting a special mention by Dr Langford at yr in review #ACR22 @RheumNow Congrats @RichardPAConway @EBRheum @jeffsparks @SattuiSEMD @rheum_cat 🎉 https://t.co/W0n7rW9pma
Patricia Harkins DrTrishHarkins ( View Tweet)
Does #COVID19 #vaccine work in #psoriaticarthritis? @RheumNow #ACR22 Abstract #0389 🤚 HR for infection and hospitalization similar between controls and PsA after 2nd vaccination 🤚#Enbrel (OR 2.39) and #JAKi (OR 9.90) higher risk of infection and hospitalization

Catherine Sims, MD DrCassySims ( View Tweet)

FDA issues an Emergency Use Authorization (EUA) for anakinra (Kineret) to treat Hospitalized COVID-19+ Patients with pneumonia requiring supplemental O2 & ! risk for respiratory failure or increased suPAR levels https://t.co/t5gFULIhCH

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Dr. John Cush RheumNow ( View Tweet)

12 pts w/ new onset IgA vasculitis (IgAV) post COVID- 19 vaccination (5F; age 52 yrs) - 10 had mRNA & 2 viral vector Vax. Time from Vax to Sxs=11.5 d; 8/12 had vasculitis w/ 1st dose; all skin (7 Jts, 4GI, 2 renal). All Rx w/ steroids https://t.co/eCcUkGeAwV https://t.co/VU1LwFxITC

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Dr. John Cush RheumNow ( View Tweet)
NY Times reports preprint article showing that taking Paxlovid w/in 5 days of COVID Test+ lowers risk of Long COVID Sxs by 26%. EMR study of 56,340 COVID pts w/ >= risk factor for severe infx; 9,217 Rx w/ Paxlovid had lesss post-Covid Sxs > 90D https://t.co/JyWEoJbUc7 https://t.co/xvTVNugwhJ

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Dr. John Cush RheumNow ( View Tweet)
The spike protein of SARS-CoV-2 drives NLRP3 inflammasome activation (one of several reasons that patient may flare or activate after COVID-19 infection or vaccination?) https://t.co/92Z14bYaUD https://t.co/iEUSgPghtT

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Dr. John Cush RheumNow ( View Tweet)
Pre and post-COVID-19 assessment of 78 FM pts by Fibromyalgia Impact Questionnaire-Revised (FIQR). While COVID affected FM pts, there was no statistically significant change in FIQR scores (65% had no improvement or deterioration on FIQR) https://t.co/S1clBCvzWm https://t.co/ZApmgvKM2c

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Dr. John Cush RheumNow ( View Tweet)
1915 Rheumatic (RMD)pts w/ COVID (42% RA. 15% SLE, 1/2 comorbidities); Outcomes: 28% hospitalized, 8% to ICU & 4% died from COVID-19. Poor COVID-19 outcomes seen w/ age, male, Hi Dz activity, steroids & RTX, & 1+ comorbidity https://t.co/ztBiJc9nxV https://t.co/RVOKyjseFJ

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Dr. John Cush RheumNow ( View Tweet)
Health Canada has approved EVUSHELD to treat COVID-19 in immunocompromised patients (it was previously approved to prevent COVID) https://t.co/ePgd4DjTka https://t.co/whgSM3ce7Q

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Dr. John Cush RheumNow ( View Tweet)
Long COVID study (54 studies, 2 databases, 1.2 million pts) showed at least 1 in 3 reported Long COVID Sx clusters (fatigue, bodily pain, mood swings, cognitive or resp Sxs), more common in women <20 yrs, w/ duration 9 mos in Hosp pts https://t.co/vuJrpWizzr https://t.co/e58J8rctEC

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Dr. John Cush RheumNow ( View Tweet)
Dr. Jack Cush goes off on "Untitling" (not using proper names/titles) in the clinic, in addition to reports on rheumatologist salaries, new drugs in phase 1-3 development and the range of COVID-19 MSK symptoms -- all from the past week on RheumNow. https://t.co/EGXslouPmC https://t.co/UVcdjzbxYp

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Dr. John Cush RheumNow ( View Tweet)
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