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ACP: Best Practice Advice on Cannabis or Cannabinoids Use for Chronic Noncancer Pain

Jack Cush, MD

The American College of Physicians published a best practice advisory on cannabis or cannabinoids in the Annals of Internal Medicine.

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Cancer Survival with TNF Inhibitors (3.28.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com

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Targeting Obesity in Rheumatic Disease Patients

Jack Cush, MD

Sattar et al. has published an informative overview of the effect of obesity on rheumatic and musculoskeletal diseases (RMDs). They estimate that nearly 70% of RMD patients are overweight or obese.

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ERA, APPs, & Alpha GAL (3.21.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.  Listen in for 2 new case questions - Ask Cush Anything.

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World Changers (3.14.2025)

Jack Cush, MD

Dr Jack Cush and his podcast friends are out to change the world. Here is his weekly review of the news and journal reports from the past week on RheumNow.

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Opioid Deaths are Down (2.28.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.  Opioid deaths are down, IL-33 levels are up and Weight loss is in the news again this week!

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Postoperative Weight Loss Improves Joint Replacement Survival

Jack Cush, MD

A cohort study of shows that postoperative weight loss with antiobesity medications significantly reduced the risk of 5-year and 10-year revision among patients with obesity undergoing hip or knee replacement.

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Drug Naming Games (2.7.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news, regulatory and journal reports from the past week on RheumNow.com.

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Daily purposeful walking assoc w/ lower risk of Knee OA (KOA). UK Biobank study of 89,969 persons, F/U 6.8 yrs - 2711 developed KOA. HRs for incident KOA were 0.84 (0.76-0.92), 0.81 (0.71-0.90), and 0.74 (0.64-0.85) if walking ~5000, ~7000, & ≥8000 steps/d, respectively https://t.co/St9QLuOy9R
Dr. John Cush RheumNow ( View Tweet)
NIH Complimentary Medicine overview of Music Therapy - preliminary research suggests that music interventions may be helpful for anxiety, depression, pain control, dementia, multiple sclerosis, Parkinson’s disease, etc https://t.co/UGsfT7lITQ https://t.co/DrJm4JdEuY

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Dr. John Cush RheumNow ( View Tweet)
Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome🧵 @NatureMedicine https://t.co/VHxmdLvoDe

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Eric Topol EricTopol ( View Tweet)
Can you distinguish which PsA? Persistent inflammatory (PIPsA) vs non-inflammatory PsA (NIPsA)? NIPsA has normal ESR/CRP, w/ obesity, biomechanical pain, OA, fibromyalgia, secondary post-inflam damage or central pain mechanisms. https://t.co/WwhdIkpJFJ https://t.co/6b5KHQRfKo

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Dr. John Cush RheumNow ( View Tweet)
Can you distinguish which PsA? Persistent inflammatory (PIPsA) vs non-inflammatory PsA (NIPsA)? NIPsA has normal ESR/CRP, w/ obesity, biomechanical pain, OA, fibromyalgia, secondary post-inflam damage or central pain mechanisms. https://t.co/9SRmpNfXCF https://t.co/wsH6poUO1m

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Dr. John Cush RheumNow ( View Tweet)
Global burden of #OA among postmenopausal women continues to escalate. From1990 to 2021, was > 1.3-fold increases in OA incidence, prevalence, DALYs. Knee OA has heaviest burden; hip OA least. Higher BMI signif influences the burden of OA https://t.co/L6qd7ISFF8 https://t.co/1SkNJWxm54

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Dr. John Cush RheumNow ( View Tweet)
Opioid Deaths are Down (2.28.2025) Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow. Opioid deaths are down, IL-33 levels are up and Weight loss is in the news again this week! https://t.co/Lb6F64AlNJ https://t.co/7AjSXOn142

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Dr. John Cush RheumNow ( View Tweet)
Postoperative Weight Loss Improves Joint Replacement Survival A cohort study of shows that postoperative weight loss with antiobesity medications significantly reduced the risk of 5-year and 10-year revision among patients with obesity undergoing hip or knee replacement.… https://t.co/u04Lc6DTT0 https://t.co/iZhEICFHUd
Dr. John Cush RheumNow ( View Tweet)
Risk factors for development of PsA in psoriasis. Psoriasis severity, obesity, and depression. @alexisogdie @RheumNow @RNL2025 https://t.co/obMDBvLLnx

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Richard Conway RichardPAConway ( View Tweet)
Can treatment of PsO prevent PsA? -Severity of PsO and obesity->Risk fx for PsA -PRESTO scores: Predicts whether you will develop PsA in the next year vs next 5 years -Does ttx of PsO impact development of PsA? Trials are mostly observational (several confounders) TriNetX data:… https://t.co/TBv3Y2TLZv https://t.co/1K0MtMQ5gn

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Adela Castro AdelaCastro222 ( View Tweet)
Predicting #PsA PRESTO study #obvious risks are #predictive Alexis R Ogdie ⁦@RheumNow⁩ #RNL2025 bad PsO 2X ^PsA High BMI Depression Modifiable risks #psoriasis #psoriatic #arthritis https://t.co/pOxidCWcg5

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Janet Pope Janetbirdope ( View Tweet)
Overweight & obesity increase risk of Chr. Inflammatory Dz (CIDs). TriNetX EHR study of >3.1 million persons shows risk of any CID=28.5% in overweight/obese vs. 17.6% in controls (HR 1.52). Overweight/obesity posed a > risk of 4 CIDs in females & also >risk for 7 CIDs in Whites… https://t.co/U5ydFGolIY https://t.co/b3Jpl27wLf
Dr. John Cush RheumNow ( View Tweet)
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