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MMWR has published the results of the 2017 Behavioral Risk Factor Surveillance System showing that increases in the number of social risk factors independently increases the odds of arthritis and its burden in the USA.
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Rheumatoid arthritis (RA) is an autoimmune inflammatory disease of the joints, characterized by pain, swelling, and ultimately, if inadequately treated, joint destruction. Despite recent advances in laboratory testing and imaging, the diagnosis of RA remains a clinical one, according to experts.
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A pragmatic, open-label trial of osteoarthritis (OA) patients demonstrated that adding duloxetine treatment seems to be beneficial for end-stage knee OA patients with neuropathic-like symptoms (at risk of central sensitization).
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Drs. Jack Cush and Artie Kavanaugh review the highlights of the RWCS (Rheumatology Winter Clinical Symposium) from Maui.
Dr. John Cush
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Korean study of 53 424 kids with Kawasaki disease (KD) showed that outbreaks of rhinovirus, respiratory syncytial virus and varicella were significantly correlated with KD at 1 to 3 months before KD outbreaks https://t.co/U8FXao1TWn
Dr. John Cush
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Live from Maui! We have a new podcast available for download— RWCS 2022 Roundup
https://t.co/UJRjdPWPmn https://t.co/BIMKdt08kK
Dr. John Cush
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Prevent NSAID GI bleeding or perforation? Korean study (n=92K) shows (vs non-prophylaxis) PPI and COX-2 inhibitors associated with 64% and 74% reduced risk. COX2 = PPI +nsNSAID. H2-receptor antag. did not reduce the risk https://t.co/VJX5nAftMf
Dr. John Cush
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144 SLE pts from the SLICC cohort were studied showing that a majority (61.2%) scores consistent with depression over 4 yrs; also an inconsistent association between disease activity and depression in multivariate analysis https://t.co/Js5jB6hlox
Dr. John Cush
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Watch: Treat to Target Strategy in RA: Dr. Dylan Lee at RWCS22
https://t.co/QExalESU2q https://t.co/cqzL4FYOUl
Dr. John Cush
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Watch: COVID-19 Triggered Anti-MDA-5 Antibody: Innocent Bystander or Culprit?
https://t.co/4MtPFM3jvS
Dr. John Cush
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Late Onset Scleroderma Renal Crisis: A Case Control Analysis - Dr. Yoon Qiu at RWCS 2022
https://t.co/G1M7Lzhk7P https://t.co/hPRL8WFdUf
Dr. John Cush
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Did Your Specialty Choose You?
Why did I end up a rheumatologist? Circumstance, personality types, horoscopes or what? A current study in BMJ sheds light on why.
https://t.co/vlO5Z8Bu60 https://t.co/y75EsGbMFF
Dr. John Cush
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C.D.C. Proposes New Guidelines for Treating Pain; the main msg - use "nonopioid therapies” for chronic & acute pain, including gabapentin, ibuprofen, PT, massage and acupuncture., https://t.co/vJeGeq8mHz
Dr. John Cush
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CSF aptamer (short nucleic acid sequences) discovery of neuropsychiatric lupus pts finds increase in few CSF proteins that are discriminatory -- CSF Lipocalin-2, M-CSF, IgM and complement C3, the latter assoc w/ acute confusional state. https://t.co/Mvp2U8DMh8
Dr. John Cush
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Using whole gut scintigraphy & gastric emptying studies on 97 systemic sclerosis pts, researchers found 35% had gastroparesis, and these pts also had abnormal transit thru out the GI tract. High anti-CENP-B titers assoc w/ slower gastric emptying https://t.co/lQgQe5Uo9H
Dr. John Cush
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ICYMI: Dr Steen's recipe to dealing with digital ulcers.#RWCS2022 @RWCSmtg https://t.co/fPblrfaFbS https://t.co/rX0hZ7rKl9
Dr. John Cush
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ICYMI: Dr Artie Kavanaugh presents comparison of targeted therapies in different inflammatory disorders. #RWCS2022 @RWCSmtg https://t.co/P4SzIrWzYJ https://t.co/wnf3vnG4xc
Dr. John Cush
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ICYMI: Retrospective study of 98 patients with X-linked agammaglobulinemia (XLA) shows arthritis seen in 46% - more oligo- than polyarthritis, affecting . Knee, hip, and ankle. IVIG response rates around 70%; many w/ arthritis had missense mutation https://t.co/qT49OXLyKU https://t.co/Drz1poV1AH
Dr. John Cush
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ICYMI: Voriconazole-induced synovitis, enthesitis and periostitis described in woman treated for invasive aspergillosis. She had polyarthralgias, synovitis, and periostitis on xray. Voriconazole prev. caused periostitis; now drug induced arthritis? https://t.co/6HfLGIaEsU
Dr. John Cush
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Best treatments for NAFLD? WEIGHT loss, but E, pioglitazone, stations, bariatric surgery. And multidisciplinary approach @UmaMahadevanIBD @RWCSmtg https://t.co/ubdFfOrWIu
