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RheumNow’s expanded coverage of the annual #ACR2020 meeting is sponsored in part by @bmsnews, @HorizonNews, @SanofiGenzyme, @Novartis. All content chosen by RheumNow & its Faculty.
Dr. John Cush RheumNow ( View Tweet)
Study of 351 SLE patients from Leiden shows that SLE with Neuropsychatric disease do not have a higher mortality than lupus without CNS disease; but do have higher mortality than gen. population #ACR20 Abstr#1264 https://t.co/CmBjfUj1Ur https://t.co/WYZQDaI4yt
Dr. John Cush RheumNow ( View Tweet)
This study identified novel RFs for RA-ILD:
Obesity
⬆CRP(≥10mg/L)
Poor function(MDHAQ ≥1)
High education
30py smoking hx assoc'd w/⬆ RA-ILD risk
Do u counsel RA pts on smoking cessation & lifestyle change? @Rheumnow #ACR20 abs1198 #ACRbest @jeffsparks https://t.co/jvZ26n8k5p
sheila RHEUMarampa ( View Tweet)
Retrospective analysis of🤰outcomes in ILD:
Live births (77%), no maternal deaths, ⬇ rates of cardiopulmonary complications.
limitations: small # of severe ILD
Multidisciplinary approach important
@RheumNow #ACR20 abs1446 https://t.co/3ayZv4XsOT
sheila RHEUMarampa ( View Tweet)
Who will clot in #Lupus? 150 with SLE, clots ^ if PC4d + = market of plt Activation & arterial thrombosis abstr#1510 needs validation in another SLE group. V interesting @RheumNow @CRASCRRheum #ACR20 https://t.co/UBGxaFwhwZ
Janet Pope Janetbirdope ( View Tweet)
ACR/AF JIA guidelines presented @ACR20:
👉Initiate DMARD early over NSAID monotherapy
👉Use SQ MTX> oral MTX > SSZ/LEF
👉add biologic preferred over triple DMARD
👉DON'T use chronic low dose steroids
👉combo biologic+DMARD > biologic monoRx
https://t.co/lwoFSTuV91
@rheumnow https://t.co/wzh2LCS0dN
k dao KDAO2011 ( View Tweet)
Study incl 1243 #SLE patients finds excess risk of #cardiovascular events is underestimated by CVD prediction tools- the underestimation may be increased in those with more severe disease activity.
Abs#1286 #ACR20 @RheumNow
https://t.co/6FZvxE02CF
Mrinalini Dey DrMiniDey ( View Tweet)
#MAS and secondary #HLH #ACR20 ABS#1150 Highlighting the use of #neopterin in following disease course and CXCL9 in active disease.- large cohort of 82 pts #IL18 marker for MAS @RheumNow #ACRbest https://t.co/166afc5Tns
Bella Mehta bella_mehta ( View Tweet)
Great poster-abstract 1260- chicken or egg- what comes first cognitive issues for patients with SLE then the Depression/anxiety or the opposite—-mental health is so important to address!! @RheumNow #ACR20 https://t.co/3ippKQN7Ap
alexa meara lexmeara ( View Tweet)
Undiagnosed AxSpA in IBD pts:
3k IBD pts, biologic naive
1⃣5% with axSpA after rheum eval
2⃣12 yr delay to dx
3⃣7% with PsO, 16% peripheral MSK symptoms
We need to be diligent and early in detection!
@RheumNow #ACR20 Abs#1309
Robert B Chao, MD doctorRBC ( View Tweet)
Post-hoc analysis of RA-BUILD & RA-BEACON: Bari-2mg showed improvement in pain, physical funxn, fatigue and MJS vs. placebo for both csDMARD-IR & bDMARD-IR @RheumNow #ACR20 abs1228 https://t.co/EIDXyJEi1q
sheila RHEUMarampa ( View Tweet)
SLE pts May have significant changes in blood brain barrier with CSF leak w changes in brain structure &cognitive function. Abstr#1508 Take #Lupus pts CNS symptoms seriously. #ACR20 #bestinclass @RheumNow @CRASCRRheum https://t.co/asgL1R9eYq
Janet Pope Janetbirdope ( View Tweet)
The roadmap to a research career includes writing a grant. @jeffsparks explains why: @RheumNow #ACR20 https://t.co/QxqQHOytNS
sheila RHEUMarampa ( View Tweet)
Dr @kaz_yos and @jeffsparks presenting that childhood parental smoking is associated with later sero+ RA even after adjustment for adult personal smoking Abstr#1000 #ACR20 @rheumnow https://t.co/7ZqwNluwaP
Richard Conway RichardPAConway ( View Tweet)
Dr Joshua presents that citrulline-reactive B cells producing pathogenic ACPAs are present in the lungs of seropositive patients with arthralgia or early RA. Supports lung as key site of initiation of RA. @rheumnow #ACR20 Abstr#1445 #ACRbest https://t.co/PBZJdQo2M9
Richard Conway RichardPAConway ( View Tweet)
Gout has high multimorbidity burden in #RISE registry, gout has more cormorbidities than RA & PsA and OA has the least & the assoc diseases are different too. Abstr#1466 @RheumNow @CRASCRRheum #ACR20 https://t.co/qPogonxDSB
Janet Pope Janetbirdope ( View Tweet)
@LeslieCrofford on building a successful career:
> priority-setting is essential
> no shortcuts to career advancement
> set your goals & prioritize your efforts
> be kind
@RheumNow #ACR20 https://t.co/G0V2IY6b4Z
sheila RHEUMarampa ( View Tweet)
Lucio phenom: a hallmark of leprosy w/erythem macules & necrotic hemorrhagic blisters that ulcerate, scar; vasculitis w/thrombus formation and endothelial proliferation can occur
#ACR20 Thieves Market Abstr#TM02: "The Dz of the Soul" ref. medieval assc w/moral turpitude @rheumnow https://t.co/YQwGphBhFC
k dao KDAO2011 ( View Tweet)
Stimulating the vagus nerve with an auricular device decreases joint inflammation and clinical symptoms in painful erosive hand osteoarthritis: the first proof-of-concept trial. Courties et al. #ACR20 >FB https://t.co/RD9xTfjjCd
ARD & RMD Open ARD_BMJ ( View Tweet)
Pain in Women with Knee and/or Hip Osteoarthritis Is Related to Systemic Inflammation and to Adipose Tissue Dysfunction and Distribution: A Cross-sectional Metabolic Biomarkers Cohort Study. Sellam et al. #ACR20 >FB https://t.co/iIdrglAilW
ARD & RMD Open ARD_BMJ ( View Tweet)