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ACR Best Abstracts - Day 1
The RheumNow faculty reporters have been glued to their monitors all day, viewing video, reading and listening to abstract presentations and I charged them to earmark those presentations were the “Best” they saw today. Below is the list of most often noted #ACRbest abstracts from Day 1.
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This convinces me! #TNF inhibitors vs #JAKI
great debate at #ACR20 https://t.co/Xb8KkmDJ8f
KenWarringtonMD MdWarrington ( View Tweet)
New treatments in Axial Spa at #ACR20. A significantly higher proportion of pts receiving Upadactinib vs placebo achieved reductions in all PGA of pain assessments and sustained to week 64 @RheumNow Abstr#369
Dr. Antoni Chan synovialjoints ( View Tweet)
Secukinumab has been used to treat spinal involvement in axial SpA. Secukinumab led to significant improvements in symptoms of peripheral arthritis in pts with AS. Significant improvements were seen in both tender and swollen joints @RheumNow #ACR20 Abstr#366
Dr. Antoni Chan synovialjoints ( View Tweet)
Axial Involvement in Psoriatic Arthritis: Perspective by Dr. Eric Ruderman @JointMD
Dr. Eric Ruderman, Chicago, IL., provides his perspective on ACR 2020 coverage of axial involvement in Psoriatic Arthritis.
https://t.co/VwrQgirJnE
Dr. John Cush RheumNow ( View Tweet)
@drdavidliew @MGHrheumatology @RheumNow That is so interesting. Haptoglobin first described by Paolaggi et al in early 1980s as having potential to monitor PMR/GCA even when ESR normalised. See link here...
https://t.co/ERkhUwssox
Dr Sarah Mackie Sarah_L_Mackie ( View Tweet)
If TCZ blunts CRP a lot/ESR a fair bit, how can we pick GCA relapses in pts on TCZ?
Cool tech (mass spec w tandem mass tag multiplex) on GiACTA samples. Of 344 candidate proteins, guess what ranked highest?
Haptoglobin.
Let's validate!
@MGHrheumatology #ACR20 ABST0513 @RheumNow https://t.co/ErmqZuf2iu
David Liew drdavidliew ( View Tweet)
@LCalabreseDO @cappelliMD @MarieKostine @EladSharonMD @rheum_covid For those who missed it, my attempt to capture some of it in a Twitter thread: https://t.co/Z55sV7ZyBt
David Liew drdavidliew ( View Tweet)
Tailoring treatment of psoriatic arthritis
#ACR20 @RheumNow
https://t.co/Ytv0vDrd95
Robert B Chao, MD doctorRBC ( View Tweet)
Check out my video on @rheumnow! #ACR20 Non-radiographic axSpa ACR Abstracts: Dr. Rachel Tate https://t.co/TVDdyZvOEA via @YouTube
Dr. Rachel Tate uptoTate ( View Tweet)
Important study helping dissect the JAK-IFN axis I believe - we need to be cautious in attacking this axis as anifrolumab has >2x Zoster of JAKi's- we need to read the tea leaves from IEIs and COVID-19 #ACR20 @JYazdanyMD @Lupusdoc @casanova_lab @cannalab1 https://t.co/scI13jwFZd
Leonard Calabrese LCalabreseDO ( View Tweet)
Abst#0170 at #ACR20 used a process called design thinking (adopted from engineering) to build a comprehensive decision aid that takes into account preferences of both patients & providers. The future of shared-decision making? @RheumNow https://t.co/DDIqm6SQev
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Axial Involvement in Psoriatic Arthritis: Perspective by Dr. Eric Ruderman @JointMD
Dr. Eric Ruderman, Chicago, IL., provides his perspective on ACR 2020 coverage of axial involvement in Psoriatic Arthritis.
https://t.co/VwrQgirJnE
Links:
Dr. John Cush RheumNow ( View Tweet)
Scoring hand x-rays for Sharp scores is painfully tedious and not always perfectly consistent.
Why not get a computer to do it? Turns out you can - a deep adaptive machine learning model does as well as a human, each x-ray in literally one second.
#ACR20 ABST0493 @RheumNow https://t.co/SvqkaFy8XZ
David Liew drdavidliew ( View Tweet)
You can watch study group sessions that you were unable to get into by clicking on the session to access the recording! #ACR20 @RheumNow https://t.co/HdFthToKQ7
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Zonulin levels ⬆ in pre-RA/RA pts; activation of zonulin signalling leads to ⬆ intestinal permeability.
Leaky gut - potential therapeutic target for RA?
@RheumNow #ACR20 abs#492 https://t.co/C4TVrWwcYG
sheila RHEUMarampa ( View Tweet)
RheumNow’s expanded coverage of the #ACR20 Annual meeting is sponsored in part by @Novartis. All content chosen by RheumNow & its Faculty.
Dr. John Cush RheumNow ( View Tweet)
If you are using PROs for Psoriatic Arthritis in clinic, listen to the session #ACR20 #2F044 Dr. Walsh sets out the pros and cons of PROs. The key things are patient and provider buy in, integrated IT system operability and avoid PROs fatigue and burden @RheumNow
Dr. Antoni Chan synovialjoints ( View Tweet)
UK Biobank data: RA is associated with not just restrictive but also *obstructive* patterns on spirometry/PFTs (independent of smoking).
Consistent observation; direction of causality? The lung in RA continues to fascinate.
Prisco @jeffsparks et al #ACR20 ABST0491 @RheumNow https://t.co/LcjtAefnVF
David Liew drdavidliew ( View Tweet)
Among a 402 pt PSS cohort, 10% fmet 2019 EULAR/ACR SLE Criteria. SSc-SLE overlap pts more likely to be female, AfricanAmerican, limited cut.SSc, U1RNP and have similar rates of severe SSc-specific organ damage /mortality. #ACR20 Abstr#0401 https://t.co/CVcFyx9AxS https://t.co/3SAKZ9CZGS
Dr. John Cush RheumNow ( View Tweet)