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New Advances in Ultrasound Diagnostics for Psoriatic Arthritis

ACR Press Release Oct 27, 2025

Two pivotal studies led by an international team of rheumatology experts will be presented at ACR Convergence 2025, showcasing major strides in the ultrasound-based diagnosis of enthesitis in psoriatic arthritis (PsA).

Screening for ILD in RA patients: CXR and PFTs by themselves are close to a waste of time. When it comes to screening (high-risk) RA patients, it’s HRCT (or lung USS) or nothing really. (in keeping with EULAR, ACR guidelines) #ACR25 ABST1335 @RheumNow https://t.co/XBDxLwYsAT

https://x.com/drdavidliew/status/1982854635577848230/photo/1

This poster is absolutely bonkers & I LOVE it Huge table. Frequency of everything over time Really interesting to see which activity persists / how much damage is accumulated Every trial should be obligated to share this (esp SLE!) #ACR25 @RheumNow #ACRBest Abst#1608 https://t.co/blRrvwi3qP

https://x.com/EBRheum/status/1982854554925293910/photo/1

Loarce et al. Poor performance of CXR and PFT in diagnosing RA-ILD (compared to HRCT). Message is, if you think they have RA-ILD, you need to do CT. @RheumNow #ACR25 Abstr#1335 https://t.co/eeSTf72mvM

https://x.com/RichardPAConway/status/1982852038548406493/photo/1

Kharouf et al. Effect of handedness on radiographic damage in PsA. Left-handedness associated increased peripheral damage, especially in left hand. Hypothesis that having to use tools designed for right-handedness increases mechanical stress @RheumNow #ACR25 Abstr#1415 https://t.co/gfGQkrYyc8

https://x.com/RichardPAConway/status/1982848012193018147/photo/1

Really useful observational study, 305 pts with TAK Out of 205 pts w/subsequent imaging, 72 (35%) w/NEW lesions in previously-unaffected territory Majority of lesions stenotic. Emphasizes importance of regular monitoring #ACR25 @RheumNow Abstr#1631 https://t.co/zoWjH0lEym

Abstract 1431: Radiographic sacroiliitis in #PsA: insights from an Indian cohort - Cervical and lumbosacral spine syndesmophytes were common - Levels C5, C6, and L4 vertebrae frequently involved including syndesmophyte damage w/ non-marginal bridging @RheumNow #ACR25

Picture this 👉radiographic joint damage tied to worse physical function in #PsA: 🔹 ↑ mSS → ↑ HAQ (β=0.003 [0.002–0.004]) 🔹 ↑ mSS → ↓ SF-36 PF (β=−0.10 [−0.15 to −0.05]) 🔹 ↑ # of damaged joints → worse physical function @RheumNow #ACR25 Abstract 1425

Abstrat 1414 Compared to #PsO, early #PsA showed: 🔹 ↑ Dactylitis (66%), Enthesitis (78%), CRP/ESR 🔹 Longer morning stiffness & ↑TJC/SJC 🔹 MRI/US: frequent tenosynovitis & bone changes 🔹 Predictive model combining these features showed Sens 89%, Spec 84% @RheumNow #ACR25

@RheumNow on virtual learning: It’s integrated in clinical care, research and #MedEd How to manage info overload? - schedule, make use of tools - use AI to curate, analyze & focus #ACR25 @rheumarhyme https://t.co/ogCezlnxUP

In the #ACR25 Great AI debate, @RADoctor shows automated ultrasound scanning - one legitimately promising application ready very soon. I’ve written about this work (ARTHUR/DIANA) for @RheumNow last year - check it out: https://t.co/Zq4ywEjspi https://t.co/3RYCVunE3a

The CLASSIC study (n=1015, 27 countries) validated revised ASAS-SPARTAN axSpA criteria. Final model achieved 79.5% sensitivity & 90.4% specificity vs global diagnosis. MRI SIJ (active + structural) was strongest predictor. HLA-B27, CRP, IBD, uveitis also included. Abstract#0854 https://t.co/GjSHE2ihVI

https://x.com/synovialjoints/status/1982814541667762292/photo/1

#0854 @Official_ASAS & @SPARTAN_Updates revised #axSpA criteria meet targets: Sn 79.5% / Sp 90.4%. Imaging is central (SIJ MRI + structural lesions) with focused clinical items: HLA-B27, IBP, uveitis, IBD, heel enthesitis, psoriasis, ↑CRP @RheumNow #ACR25 https://t.co/i2d12y9HcD

https://x.com/DrMiniDey/status/1982817310122344676/photo/1

The severity of skin psoriasis increases the risk of psoriatic arthritis. Scher J @RheumNow #ACR25 https://t.co/EI0ACWACHy

https://x.com/synovialjoints/status/1982559833179193832/photo/1

We need more biomarkers in GCA - what about fibrinogen? Miller et al retrospectively compared CRP, ESR, and fibrinogen at different points in GCA dx Fibrinogen (and ESR/CRP) only helpful prior to initiation GC with comparable performance @RheumNow #ACR25 Abst #0750 https://t.co/q5gFxDMnTy

https://x.com/Dr_Brian_MD/status/1982557897369530485/photo/1

Can tissue give us an underlying diagnosis in aortitis? Dr. Kermani breaks down the autoimmune differential based on histopathology @RheumNow #ACR25 https://t.co/twcH021dxS

https://x.com/Dr_Brian_MD/status/1982556819118776511/photo/1

#Cancers esp #hematologic & #lung are ⬆️in Pts w #inflammatory #rheum #diseases Odds ratios of hem malignancies are wide & risk stratification is imp Are we doing a good job? 🤔skin cancer screening ??- not as per general standards Abst#0172 #ACR25 @RheumNow @ACRheum https://t.co/Uve9knXD3o

Phenotypes of GCA: Pt dx by PET compared to TA biopsy were: - younger -longer disease before dx -more frequent extremity claudication (still overall low) -less cranial / TA sx @RheumNow #ACR25 Abstract 0759 https://t.co/ilwa3eYmRq

https://x.com/Dr_Brian_MD/status/1982492391803408736/photo/1

Miller et al. Fibrinogen for GCA diagnosis and flare identification. Similar to ESR/CRP in diagnosis. For flares, lower sensitivity (79%) but better specificity (96%) @RheumNow #ACR25 Abstr#750 https://t.co/SIkAkEeYh1

https://x.com/RichardPAConway/status/1982484365751075203/photo/1

Observational study of fibrinogen for diagnosis of GCA At a cutoff of 4.7, roughly similar diagnostic performance as compared to ESR/CRP Kind of neat, but does not appear to have additive benefit #ACR25 @RheumNow Abstr#0750 https://t.co/xy2qn4jHXP

https://x.com/EBRheum/status/1982481345915040253/photo/1

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New Advances in Ultrasound Diagnostics for Psoriatic Arthritis

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