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Rheumatoid Arthritis Antibodies Linked With COPD
Women who were seropositive for anti-citrullinated protein antibodies (ACPA) and ultimately went on to develop rheumatoid arthritis (RA) were also at increased risk for being diagnosed with chronic obstructive pulmonary disease (COPD), analysis of data from the Nurses' Health Study showed.
Read ArticleBook Review: “Great Health Care Value: Chronic Diseases, Practice Teams and Population Management”
The US healthcare market has evolved into an incredibly expensive system that often does not deliver good medical outcomes. While most of us know these problems exist, we rarely have up-to-date data or can offer alternatives to the way we manage care, especially to the chronically ill who consume much of our health care dollars. In their book, authors Tim Harrington, MD and Andrew Johnson, MS, MBA offer insights, evidence and experience on how we may do our part to improve the management of chronic rheumatic/orthopedic issues.
NSAIDs May Impair Healing if Taken Nightly
A new study in Scientific Reports suggest that circadian rhythms play an important role in wound healing, and that nonsteroidal anti-inflammatory drugs (NSAIDs) may be disruptive if taken at night given primary healing that occurs in a body at night.
Read Article2019 EULAR Recommendations for the Management of Rheumatoid Arthritis
The 2019 update to the EULAR recommendations on the use of synthetic and biological disease-modifying antirheumatic drugs in rheumatoid arthritis (RA) have been published in Annals of Rheumatic Disease - highlighting the efforts of an international consensus committee effort.
In the end, the task force put forth 5 overarching principles and 12 recommendations concerning use of conventional synthetic DMARDs, glucocorticoids, biological DMARDs, biosimilar DMARDs, and targeted synthetic DMARDs (the Janus kinase (JAK) inhibitors tofacitinib, baricitinib, filgotinib, upadacitinib).
RheumNow Podcast- A Good First Impression (1.24.20)
Dr Jack Cush comments on this week's journal articles, reviews and studies.
Read ArticleProspectively study of neuropsychiatric (NP) events in1827 SLE - found that NP-SLE occured in 52%; with 31% directly attributed to SLE. Risk of NP-SLE was highest in the first 2 years (RR 6.16) and mortality risk was higher in NP-SLE pts ((16% vs 7%) https://t.co/03wfX5SxNm
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Study of 260 TB patients treated with pyrazinamide or fluoroquinolones showed a higher risk of joint pain (mostly ankles knees) with FQN (29%) vs PZA (17%); median latency was 55 days vs 138 days; half had hyperuricemia. https://t.co/ylc4Az0yOz
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ENTRACTE trial studied the risk of major adverse CV events (MACE) in 3080 RA pts Rx with tocilizumab (TCZ) vs etanercept (ETN), and found no increased risk of MACE in TCZ patients compared to ETN (HR 1.05 (95% condence interval 0.77–1.43). https://t.co/QxOlzfDcZD
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New ACR guidelines for OA hip/knee give a conditional recommendation for Balance exercises. https://t.co/2YLKuhZ92M A systematic review of 11 studies shows Knee OA pts at risk for falls. Risk factors: impaired balance, weakness, comorbidities, # of joints https://t.co/fAzYHtIpEM
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Minna Kohler, MD, RhMSUS minnakohlermd ( View Tweet)
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