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Chikungunya - takeaway points
🪔Acute arthritis in large joints , polyarthritis and tenosynovitis in hands
🪔 Associated with travel history to Africa/Asia/Asia Pacific
🪔<5% develop chronic arthritis
#ACR23
#ACRambassador https://t.co/yzZDpy70i3
Tanmayee Bichile, MD ( View Tweet)
As per #ACR23 ABST0433, what % of RA patients on US Medicare are on a DMARD within 1y of diagnosis?
I'm not talking your choice of b/tsDMARD.
I'm talking any cs/b/tsDMARD of any sort.
Hear from @JihaRheum to skip to the answer:
https://t.co/lI2M20JWKC
Truly stunning. @RheumNow
David Liew drdavidliew ( View Tweet)
INSIST trial: MMF vs Tac in SS-ILD
N=25 pts
👉No significant diff between MMF & TAC in mean change in FVC at 24 weeks [2.52%, 95% CI (-10.3 to 5.18)p=0.500]
👉No SAEs noted in both grps
Larger studies w/ longer ffup needed.
#ACR23 ABST2595 @RheumNow https://t.co/cqpnxyMDmv
sheila ( View Tweet)
Dr. @Janetbirdope has the best quotes ever ‘ if its ain’t broke, don’t fix it, just leave it alone’ 🤷🏻♀️
IGg4 is very interesting , could just be reacting / secondary to an underlying phenomenon?
https://t.co/hueCJuYI32
@RheumNow
#ACR23, Daily recap.
Nouf Al hemmadi ( View Tweet)
Here at Last: Treatment Options for VEXAS
We have known about the VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome for nearly 3 years, but there has been relatively little to say about how to treat it. To date there have been over twice as many publications about VEXAS (263 publications) as there have been patients described with respect to treatment strategies (116 patients). One of the late breaking abstracts may finally have rectified this imbalance.
Read ArticleAre Rheumatologists doing Enough for Cervical Cancer?
Should rheumatologists be counseling patients on cervical cancer prevention and screening?
Read Article
Is MSOT the New Ultrasound?
Dr. Aurelie Najm reports on oral abstract 0750 presented at #ACR23
https://t.co/okbGHTR0i3 https://t.co/9zkHPiFl74
Dr. John Cush RheumNow ( View Tweet)
A randomised clinical trial show improvements in clinical outcomes CDAI, VAS for both the ITIS diet and the Med diet. Baseline differences in the microbiome between responders and non-responders were seen. Sala Climent M, Abst#2124 #ACR23 @RheumNow https://t.co/tiyNcV7cmD https://t.co/EEP4zrwjXs
Dr. Antoni Chan ( View Tweet)
Fecal transplant for treatment of GI complications of systemic sclerosis?
No change in those who received transplant...
Overall procedure safe
@RheumNow #ACR23 Abs#2597 https://t.co/TEdeGHuzpi
Robert B Chao, MD ( View Tweet)
What's the long-term mainentance game plan in IgG4-RD?
WInS IgG4-RD study
China, n=146
IgG4-RD stable disease >12mo
Withdrawing both IM+GC completely has much higher relapse rates vs at least keeping some IM
IgG4-RD needs some steroid-sparing Rx ongoing
#ACR23 L16 @RheumNow https://t.co/1JJpQmFTF5
David Liew drdavidliew ( View Tweet)
L18 @ #ACR23
⭐️Clinical Implications in Primary Sjögren's Syndrome (pSS) by Molecular classification of Salivary Glands (SGs)
➡️ transcriptomic profiling of SGs in Chinese cohort
👉 396 pSS, 87 non-pSS, & 44 early-pSS
➡️ 3 distinct sub-types:
⭐️Pacui-immune/C1… https://t.co/3ZdrghCB6F https://t.co/hZ9S3hvCzv
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Withdrawing immunosuppression and steroids in IgG4-RD
Maintaining immunosuppression with or without steroids associated with low relapse rate
52% of pts who withdrew steroids +immunosuppression relapsed
@RheumNow #ACR23 Abs#L16 https://t.co/xJyDiCkMVD
Robert B Chao, MD ( View Tweet)
Inflammation in interstitial fibrosis & tubular atrophy (i-IFTA) is assoc w/ GFR loss accdg to this study by Dr SMalvica et al.
✳️In pts w/ mod-to-severe IFTA, the degree of i-IFTA was assoc'd with higher risk of GFR loss
#ACR23 ABST2552 @RheumNow https://t.co/7iA0nzbmgM
sheila ( View Tweet)
Beware of the « HOT stuff 🌶️ bias »
In his very didactic catalogue of bias, Timothy McAlindon particularly warns us against the hot stuff, or the tendency to be less rigorous in the scientific approach when a topic is fashionable
@RheumNow #ACR23 https://t.co/rS8lItDrGS
Aurelie Najm ( View Tweet)
#ACR23 Abstr#2580 Could high-intensity resistance training improve outcomes in myositis? RCT showed 16 wks of training was tolerable, improved quality of life & functional capacity, without increasing disease activity/damage @RheumNow https://t.co/O1nP2x9C1L
Md Yuzaiful Md Yusof ( View Tweet)
TM66 at #ACR23
60 yo M w/ worsening PMR symptoms (polyarthralgias, difficulty raising arms) & b/l vision loss
PMH: PMR, central serous chorioretinopathy, HTN
VS: 100.2 F, HR 108
Labs:
- CRP 100 mg/dL, ESR 81 mm/h
- UA: proteinuria (100 mg/dL)
- ANA > 1:10,000, dsDNA > 300… https://t.co/T7Nov5vyoc https://t.co/3GuXVgh03Z
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Patella tendon characteristics with USG - thickness, cross sectional area and stiffness measures with shear wave elastography
In pts with or without knee pain
@rheumnow #ACR23 52 pts Pain didnt correralate with thick ess and cross sectional area but did correlate with stiffness https://t.co/q3ZPG1l2n2
Bella Mehta bella_mehta ( View Tweet)
Plenary Abs #2425: Pregnancies among vasculitis pts - higher frequency of spontaneous abortion and preterm delivery. Risk of maternal complications associated with vasculitis were observed to vary by vessel size and parity. #ACR23 https://t.co/qLcpNapcjg @rheumnow https://t.co/sk3dhySVfP
Dr. Rachel Tate ( View Tweet)
So great to see posters back at #ACR23 and interactions of #students and #mentors which can be career shaping. Data from #Alberta with a nearly 3K survey on #cannabis use in Pts with #rheumatic diseases studying the use as #Rx and #recreational @RheumNow #979, 980 https://t.co/xbVcK5HuRS
Janet Pope ( View Tweet)