Researchers from Germany have analyzed their large prospective rheumatoid arthritis (RA) registry to address whether being on biologic therapies leads to poorer outcomes - namely sepsis or death, following a serious infection (SIE).
Researchers from the radiology department at University of California, Davis Health System have studied the phenomenon of knuckle cracking by simultaneously recording audio and ultrasound imaging from 17 women and 23 men. The group included 30 habitual knuckle crackers and 10 who were not.
Some individuals cracked their knuckles up to 20 times per day for the past 40 years.
Dr. Cush reviews the RheumNow.com highlights in rheumatology for the week ending 19 August 2016.
The goal in rheumatoid arthritis (RA) treatment is remission. But what level or method of remission is best? Using clinical parameters, there are numerous definitions of remission to choose from (ACR boolean, CDAI, SDAI, etc.) and not all measures perform equally when applied to the same patients.
A U.S. court has affirmed its decision that the patent for Johnson & Johnson's drug Remicade is invalid. This new ruling favors the intent of Celltrion and Pfizer, who are seeking to bring their biosimilar versions of infliximab to market in the near future.
Remicade has been Centocor's (J&J's) best selling product, with $6.6 billion in sales last year. The drug's patent will lapse in September 2018.
People with hyperuricemia who followed the blood-pressure-lowering DASH diet showed significant decreases in serum urate levels, post-hoc analysis of data from an influential randomized study found.
In the Dietary Approaches to Stop Hypertension (DASH) study, participants adhering to the diet, which emphasizes the consumption of vegetables, fruits, and low-fat dairy foods as well as whole grains, poultry, fish, and nuts, had a mean decrease in
A new national survey in the United States of nearly 600 individuals with psoriasis, reveals that although patients have numerous treatment options, they have difficulty finding treatment plans that work. In addition, respondents reported a heavy emotional toll, with many feeling isolated and stigmatized due to the condition.
Tobacco and chronic smoking is a major risk factor for the onset of rheumatoid arthritis (RA), and chronic smoking has been linked to severity of disease and lower DMARD response rates. None of this is surprising given the known higher risks for RA in those with ACPA seropositivity, the shared epitope and cigarette smoking.
Myelodysplastic syndrome may infrequently present with inflammatory or autoimmune symptoms. This literature review shows a variety of presentations and treatment options for such patients.
Rheumatologists are well-acquainted with the rules for hydroxychloroquine (HCQ) retinopathy screening: A) annual visits to the ophthalmologist and B) maintain HCQ doses at less than 6.5 mg/kg to avoid retinopathy. But...not only are we not so well acquainted, there are new guidelines from the AAO.
In 20111, the American Academy of Ophthalmology published revised recommendations regarding HCQ screening.
Watch Dr. Cush review 13 highlights from this week on RheumNow.
SHARE (Single Hub and Access point for pediatric Rheumatology in Europe) is a group established in 2012 to develop and optimize diagnostic and management regimens in Europe for children and young adults with rheumatic diseases.
Warnings of cancer, especially lymphoma, have accompanied the development and promotion of tumor necrosis factor inhbitors (TNFi) in the treatment of RA and other inflammatory disorders.
The pathogenesis of Alzheimer's disease (AD) is unknown but some have speculated a role for inflammation.A group of investigators assessed the frequency of AD in and inflammatory disorder, rheumatoid arthritis (RA) and if effective therapy with TNF-α inhibitors (TNFi) would lower the risk of AD in RA patients.
