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Promising Therapies for Sjogren's
Adult-onset Still’s disease is a rare complex, sporadic, systemic autoinflammatory disease similar to systemic juvenile idiopathic arthritis characterized by sustained fever, salmon-colored rash, and arthritis. The 2023 ACR convergence featured several abstracts spotlighting developments in understanding and managing this complex disease spectrum.
Calcineurin Inhibitors in Lupus Nephritis

Dr. Kathryn Dao discusses abstract 1509 with Dr. Gabriel Figueroa-Parra at t

Dr. John Cush RheumNow

2 years 10 months ago
Calcineurin Inhibitors in Lupus Nephritis Dr. Kathryn Dao discusses abstract 1509 with Dr. Gabriel Figueroa-Parra at the 2023 ACR Convergence meeting in San Diego, CA. https://t.co/4CjJ8Ri3ym https://t.co/KUONVdMfBB
How do we Diversify Clinical Trials?

Dr. Rachel Tate talks with Dr. Irene Blanco at the 2023 ACR Convergence meeting i

Dr. John Cush RheumNow

2 years 10 months ago
How do we Diversify Clinical Trials? Dr. Rachel Tate talks with Dr. Irene Blanco at the 2023 ACR Convergence meeting in San Diego, CA. https://t.co/fZ7kKfdRwP https://t.co/Non3X7zOxA
Is MTX Safe in the Elderly?

Dr.Cush reviews this past week's news from RheumNow. Good news is that nearly 99% of adul

Dr. John Cush RheumNow

2 years 10 months ago
Is MTX Safe in the Elderly? Dr.Cush reviews this past week's news from RheumNow. Good news is that nearly 99% of adult rheumatology positions matched! But 45% of pediatric fellowship programs and 39% of pediatric rheum slots were unfilled. https://t.co/un9CbyYooL https://t.co/ilABvgr7bH
Since the millennium, we have seen an expansion in the number of advanced treatments both biologic and targeted synthetic disease modifying anti-rheumatic drugs for rheumatoid arthritis. The challenge remains on how best to characterise the subtypes of RA in order to choose the best drug to ensure optimal outcome for patients. 
A recent New England Journal review of post-menopausal osteoporosis (OP) provided updated information, strategies and a review of guidelines and clinical recommendations. Here are the salient highlights.
Few people are aware of the EULAR recommendations for cardiovascular risk management in SLE published in 2022.  The recommendations had 4 overarching principles: increase awareness of elevated cardiovascular risk, need for regular cardiovascular screening, assess and manage modifiable risk factors, and patient education. During ACR 2023 Convergence, several abstracts were presented evaluating the prevalence of CV disease and exploring new
resolved HBV (HBsAg-, HBcAb+, HBsAb+) are at low risk of reactivation (~2%) w/ TNFi or biologics. But in a high risk end

Dr. John Cush RheumNow

2 years 10 months ago
resolved HBV (HBsAg-, HBcAb+, HBsAb+) are at low risk of reactivation (~2%) w/ TNFi or biologics. But in a high risk endemic region (ie, Korea) this risk is higher. Study of 416 such pts HBV reactivation rate 3.5% @5 yrs, 6.1% @10 yrs & 24.2% @17 yrs https://t.co/oQ5e6O9wds https://t.co/50vBtapJVN
Risk of Hepatitis B reactivation is assessed by serology
- Resolved HBV (low risk reactiv): HBsAg-neg, HBcAb–pos &

Dr. John Cush RheumNow

2 years 10 months ago
Risk of Hepatitis B reactivation is assessed by serology - Resolved HBV (low risk reactiv): HBsAg-neg, HBcAb–pos & Pos HBsAb - If HBcAb(+), HBsAb negativity incr risk; - HBsAg(-), HBcAb(+), HBsAb(-) negative= resolved infx, occult infx, chronic hepatitis https://t.co/91ZwqWkdvo https://t.co/c23nN8ER1Y
#RA pattern of synovitis is well knownn & decr in grip strength seen in Early (39%) & later RA (59% @5y). MCP1 s

Dr. John Cush RheumNow

2 years 10 months ago
#RA pattern of synovitis is well knownn & decr in grip strength seen in Early (39%) & later RA (59% @5y). MCP1 synovitis impacts grip strength most (60%) followed by MCP4 (much less w/ tender/swelling of PIPs,other MCPs). Based on study of 215 early RA pts https://t.co/rTFBHKlNGV https://t.co/zCVsTNuYWW
Rheum Fellowship Slots Fill Up for 2024

The NRMP announced yesterday that the 2024 rheumatology fellowship match fille

Dr. John Cush RheumNow

2 years 10 months ago
Rheum Fellowship Slots Fill Up for 2024 The NRMP announced yesterday that the 2024 rheumatology fellowship match filled 97.6% (124/127) of programs, and 98.9% (273/276) of rheumatology fellowship positions. https://t.co/wTwajHyal0 https://t.co/JpgDUmioQh
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