Incidence of Psoriatic Arthritis Among Psoriasis Patients Save
Researchers at the University of Toronto have prospectively studied a cohort of 464 psoriasis patients without a diagnosis of arthritis and followed them over 8 years to estimate the incidence and frequency of psoriatic arthritis (PsA).
During the 8 years of follow-up, 51 patients developed PsA; with an annual incidence rate of PsA was 2.7 cases (95% confidence interval 2.1–3.6) per 100 psoriasis patients.
In multivariate analysis, variables that were predictive for the development of PsA included severe psoriasis (RR 5.4), low level of education (RR 0.22), retinoid use (RR 3.4), nail pitting (RR 2.5) and uveitis (RR 31.5).
The observed incidence of PsA in patients with psoriasis is higher than previously reported and may be suspected moreso in those with a severe psoriasis phenotype, presence of nail pitting, low level of education, and uveitis.
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