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JAKi and TYK2i: What to use and when?

You can see that the JAKi/TYK2i have both approved or potential seropositive and seronegative indications. There are also improvements in PsO for the class and studies in CTDs. So, it is difficult to know which to choose.

Rheumatology Roundup - ACR 2023

Drs. Jack Cush and Arthur Kavanaugh discuss highlights and key takeaways from ACR 23.

This included the following abstracts:

#ACRbest Abstracts – Day 4

While there wasn’t much original new programming and research presented on the final day, that didn’t slow the RheumNow faculty from tweeting the noteworthy “Best of ACR” abstracts.  Enjoy these below.

ACR 2023 – Day 4 Report

The last day at ACR23 was a ghost town as most left, largely because there was limited programming on the fourth and final day. The main attraction on Day 4 was the late-breaking abstract – oral presentations.

#ACRbest Abstracts – Day 3

Today was a big day for the Plenaries, Curbside Consult

Day 2 Report - ACR Plenaries: Changing the Practice of Rheumatology

The Merriam-Webster definitions of “plenary” include: 1. complete in every respect: absolute, unqualified and 2. fully attended or constituted by all entitled to be present.

#ACRbest Abstracts – Day 2

Our reporters have been prolific in finding the hot abstracts, those that were most attended or those that are getting the most buzz on social media.  Here are RheumNows #ACRbest abstract reports from Monday, November 13, 2023 at #ACR23. 

THE GREAT DEBATE

Pregnancy Updates That Will Change The Way I Practice

ACR Convergence is truly drinking from the proverbial fire hose. It’s a beautiful mash-up of basic science and treatment updates meets guidelines, recommendations, and disease identification.

Subcutaneous Biosimilars? (10.27.2023)

Dr. Jack Cush reviews RheumNow's top entries the PMR Campaign, news, journal reports and regulatory actions.

Methotrexate in OA (10.20.2023)

Dr. Jack Cush discusses the news, journal articles and regulatory actions. This week we discuss JAKne, DLE and SLE and more.

RheumNow Podcast – with Special Guest Dr. Kathryn Dao (9.29.2023)

This week on the podcast, Dr. Jack Cush is joined by special guest, Dr. Kathryn Dao to review the news and journal reports from the past week on RheumNow.com. They discuss unmet needs in gout, obesity and CV disease in PsA and should you check ANCA antibodies in SLE?

Focus on the Fasting Lipid Profile

There has been much discussion of late regarding the important topic of how best to manage the independent cardiovascular risk associated with rheumatoid arthritis and other rheumatic diseases.

Social

Mycophenolate isn't great for vaccine immunogenicity, but withholding MMF for one week after both doses of recombinant zoster vaccine boosts Ab titres ++ in this Brazilian RCT. A week off post-vaccine: definitely worth considering in stable disease #ACR24 ABST0247 @RheumNow https://t.co/lajS5DzRbD
David Liew @drdavidliew ( View Tweet )
10 months ago
CKD keeps a persistent low grade inflammatory state! Implications: CKD ⬆️risk for CV dz through different mech @RheumNow #ACR24 https://t.co/KcCvyTVaav
TheDaoIndex @KDAO2011 ( View Tweet )
10 months ago
#ACR24 Ab#0771 ARID5B - transcription factor controls pathologic inflammatory fibroblast ARID5B: RA risk locus on GWAS, also link to SLE, Graves Binds to histone editors to epigenetically regulate fibroblast state ARID5B deletion incr inflamm response, overexpr decr @RheumNow https://t.co/ebKnX1uTuO
10 months ago
Save the date! RheumNow will be covering #ACR24 from 11/14-11/19. Get ready for daily recaps, live streaming and much, much, more! https://t.co/rDMFH3wlbc
Dr. John Cush @RheumNow ( View Tweet )
10 months 1 week ago
Save the date! RheumNows will be covering #ACR24 from 11/14-11/19. Get ready for daily recaps, live streaming and much, much, more! https://t.co/uKc14y1fOm
Dr. John Cush @RheumNow ( View Tweet )
10 months 2 weeks ago
Hydroxychloroquine effects studied in 30pts (23 RA, 7SLE). Results did not support that HCQ may reduce CV risk - Arterial stiffness was not affected by HCQ, HCQ modestly lowered HbA1c & lipids - yet HCQ has been shown to reduced CV risk in observational studies… https://t.co/n283HwvRm4 https://t.co/lQN342uevy
Dr. John Cush @RheumNow ( View Tweet )
10 months 2 weeks ago
Blue Collar Arthritis (10.25.2024) Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow. https://t.co/INcke6eLLC https://t.co/TGyxzmCrjv
Dr. John Cush @RheumNow ( View Tweet )
10 months 3 weeks ago
Early bird pricing ends 10/31. Secure your seat for RheumNow Live today! https://t.co/TBNLxfBbEF https://t.co/6OLHEXCvUw
Dr. John Cush @RheumNow ( View Tweet )
10 months 3 weeks ago
ANA+ consult (10.18.2024) Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow. https://t.co/cH4s99Fzka https://t.co/kNcUqahmeS
Dr. John Cush @RheumNow ( View Tweet )
10 months 4 weeks ago
Dr. Lindsey Criswell Elected to National Academy of Medicine. Dr. Criswell is the NIAMS Director and is known for her research in SLE, RA, and Sjogrens. Congrats!! https://t.co/3l4VHqnH2m https://t.co/FDcNVGjw4l
Dr. John Cush @RheumNow ( View Tweet )
11 months ago
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