RNL23 Replays (5.6.2023) Save

This week on the podcast we feature replay content from RNL 2023, cannabis effects on pain and sleep, and what drives PJP risk the most - steroids or RTX?

1. QD Clinic - Audience RA Questions from RNL23 https://t.co/vh1Tzstbwl

2. #RNL2023 @RheumNow There are a lot of RA Rx on market now - do we need more? Dr. Brenner: YES Stromal targets like LIF/LIFR, Notch3, cadherin-11 offer upstream benefits for our difficult to treat RA patients that don't respond to tradition cs/bDMARDs https://t.co/xavJrFX84G

3. Treatment with MTX in early CCP+ RA thought to be effective in slowing disease however StopRA study did not show a difference between HCQ and PBO in patients. We need to know more about HCQ vs MTX in this space! #RNL2023 https://t.co/hkypaEwZ8F

4. ACR 2023 Convergence Brings Back the Poster Hall and 4 Day Meeting ACR Convergence 2023, the annual meeting of the ACR and the world’s premier rheumatology experience, will be held Nov. 10 – 15 at the San Diego Convention Center in San Diego, CA. https://t.co/2yFL5m5Y4f

5. How do you prevent RA in at-risk patient? Smoking cessation! Healthy weight and exercise! Diet! Periodontal health! 🚭🏋️🥕🦷 Education follow-up! Not robustly proven to prevent/delay RA, but may be more important than early DMARD intervention! Kevin Deane, MD #RNL2023

6. Korean retrospective claims analysis of #RA (n=54 .7K; 39K RF/CCP+) (2010-2019; F/U 4.3 yrs) saw Parkinsons dx in 290 RA; Compared to controls, RA had a significant 1.74-fold higher risk of PD (found in seropos HR 1.95) but not seroneg RA https://t.co/GRahCXDuYt

7. 5 year retrospective study of hip replacements (w/ RA, PsA, OA, AS pts), looked at those w perioperative TNFi vs stopped TNFi; showing no differences in outcomes (p = 0.713)> @ last F/U, revision rates were TNFi 2.5%, nonbiologics 3% & 0.8% OA THAs https://t.co/fMKJLyMO6A

8. Pharma marketing payments to MDs (none; < $100; >$100) correlated with Medicare billing of Intraarticular Hyaluronic Acid injx. In 20 501 MDs, 41.5% gave HA injx; Odds incr w/ payment <$100 (OR 2.06) or >$100 (OR 3.28); 12.7% & 21% more likely https://t.co/BP395xm0TW

9. Observational study of cannabis use in 25 cancer pts (52% w/ colon/lung/breast CA) taking a 2-wks of ad libitum cannabis noted to have improvements in pain intensity, pain interference, sleep quality, & cognitive function,but no change in quality of life. https://t.co/iZjGMM1Pud

10. PJP Prophylaxis Needed with Steroids and Rituximab

11. Join us this Tuesday for our Tuesday Night Rheumatology focusing on Modern Management of Psoriatic arthritis Tuesday, May 9, 2023. Register here.