Abuse of the Safety-Net 340B Drug Programs

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Dr. Madelaine Feldman has written an important commentary on the 340B Drug Pricing Program, a safety-net program that would allow vulnerable populations to receive expensive new therapies. But she points out that "this well-intentioned program has strayed from its original purpose", allowing certain hospitals and for-profit pharmacies to exploit the program.

ICYMI: JAKi in inflammatory myositis?

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Abstract 1731 is a small RCT of baricitinib in inflammatory myositis comparing early start baricitinib to later start.

Tocilizumab Efficacy in Giant Cell Arteritis Phenotypes

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Biosimilars Do Impact Biologic Drug Costs

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Introduction of biosimilars for the rheumatology drug adalimumab, whose original branded version Humira has long been a blockbuster, appears to have led to a dramatic drop in net spending for these products -- even though biosimilars barely dented Humira prescription rates.

ICYMI: Sex related differences in PsA

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Different factors are known to influence disease characteristics and outcomes in psoriatic arthritis (PsA).

ICYMI: Beyond the Needle: Redefining the Assessment of Lupus Nephritis

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Lupus nephritis is one of the most silent and severe manifestations of SLE. When not captured early, patients are at high risk of progressing to end-stage renal disease, which would require dialysis or transplantation. Renal biopsy remains the gold standard for diagnosis and disease classification. However, the procedure is invasive and very painful. Non-invasive measures are critical for early detection and continuous monitoring.

ICYMI: Are Emulation Trials a Fantasy?

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Are emulation ‘trials’ helpful, despite the biases that occur with observational data, or do they truly mimic the results of randomized controlled trials (RCTs)?

54K Peptic Ulcers Annually (12.13.2024)

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Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com

Rheumatoid Arthritis Boosts Risk for Some Types of Heart Failure

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Rates of heart failure with preserved ejection fraction (HFpEF) were doubled in patients with rheumatoid arthritis (RA) relative to other people of the same age and sex, researchers found.

Safety of Acetaminophen in the Elderly

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New research, led by experts at the University of Nottingham, has found that repeated doses of paracetamol in people aged 65 and over, can lead to an increased risk of gastrointestinal, cardiovascular and renal complications.

ICYMI: Say Goodbye to Methotrexate in PMR?

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For decades, glucocorticoids (GCs) have formed the backbone of polymyalgia rheumatica (PMR) management.

Outcome of Pain in Hand Osteoarthritis

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Leiden cohort study of hand osteoarthritis (HOA) patients shows that over 4 years, pain outcomes are variable, and not inevitably worsening.