Coccyx and Sacrococcygeal Joint Disorders

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Pain from coccygeal or sacrococcygeal disorders is rare, often presenting as a diagnostic challenge. Coccygeal pain is often mistaken for lumbosacral, pelvic, or gastrointestinal disorders.

Treating Refractory Still's Disease

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Chronic pain may dramatically raise your blood pressure

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Widespread chronic pain may stealthily drive up blood pressure, partly through its ties to depression and inflammation.

Managing Perioperative DMARDs with Arthroplasty

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Postoperative complications with arthroplasty may be related to chronic inflammation and immunosuppressive therapy. Yet a recent retrospective study total ankle arthroplasty in end-stage RA patients shows that early postoperative wound complications are unaffected by the continued use of their preoperative medications including DMARDs.

Partial vs Total Knee Replacement: Is One Superior?

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Patients with osteoarthritis (OA) primarily affecting only one knee joint compartment did just as well with partial knee replacement (PKR) as with total arthroplasty after 10 years in a randomized trial -- and maybe a little bit better. Final results of the landmark TOPKAT study indicated that rates of the most clinically important outcomes were nearly equal between the two procedures, according to David Beard, DPhil, GDPhys, MCSP, MSc, of the University of Oxford in England, and colleagues. These similarities included Oxford Knee Score (OKS) values both at year 10 and cumulatively during the entire follow-up period, as well as reoperations and revisions.

Vitamin D and Lupus Outcomes (11.21.2025)

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Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

Organ Involvement with Behçet’s

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A review of patient data from the International AutoInflammatory Disease Alliance (AIDA) Network registry identifying those with mucocutaneous Behçet’s disease (BD) may progres to major organ involvement (MOI)m especially at later stages.

A New Disease Activity Score for Antiphospholipid Syndrome?

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APS is a systemic autoimmune disorder. It is characterised by the presence of antiphospholipid antibodies and a broad spectrum of clinical features, causing obstetric as well as thrombotic, microvascular and non-thrombotic (TMN) symptoms.

APEX Study: Inhibition of structural damage progression with Guselkumab in Psoriatic Arthritis

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Guselkumab, a human IL-23 inhibitor, was evaluated in patients with active psoriatic arthritis (PsA) and shown to have both clinical and radiographic benefits at weeks 24 and 48.

Pulse Steroids and Mycophenolate in Juvenile Dermatomyositis

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JAMA Dermatology has published a pilot study demonstrating the safety and efficacy of intermittent intravenous methylprednisolone pulse (IVMP) therapy plus mycophenolate in 28 patients with juvenile dermatomyositis (JDM).

Seeking Musculoskeletal Care

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A report entitled The Burden of Musculoskeletal Diseases in the United States (BMUS) report was published by the US Bone and Joint Decade (USBJD) with input from rheumatology, orthopedic surgery, physical medicine and rehabilitation regarding musculoskeletal care.

Rheumatology Supply and Demand (2009 - 2024)

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A retrospective review of US rheumatology manpower and training between 2009 and 2024 shows that US rheumatology training has become competitive with an increasing surplus of applicants compared to available training positions, which have also increased over time.

ACR Applauds Bipartisan Support for Prior Authorization Reform Bill

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The American College of Rheumatology (ACR) today commended the more than 295 bipartisan, bicameral cosponsors of The Improving Seniors’ Timely Access to Care Act, which, if enacted, would reform the prior authorization process for Medicare Advantage plans.

25-Hydroxyvitamin D levels and Lupus Outcomes

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Lupus patients entering a prospective cohort study with low vitamin D levels faced doubled all-cause mortality risk and tripled risk for major cardiovascular events during follow-up averaging 6 years, researchers said.

Treating During Pregnancy (11.14.2025)

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Dr. Jack Cush reviews the journal articles, news and guidelines from this past week on RheumNow.com