Skip to main content

News

Prevalence of Inflammatory Bowel Disease Increases

The MMWR has reported that Crohn’s disease and ulcerative colitis, collectively known as inflammatory bowel disease (IBD), previously (1999) had an estimated 1.8 million (0.9%) prevalence. But as of 2015, an estimated 3.1 million (1.3%) of U.S.

Is There a Familial Risk to Scleroderma?

Using population based data, researchers found a 10 fold increase prevalence of SSc in first degree relatives. That equates to a relative risk of 81. Genetic factors appear to be important in the risk for scleroderma.

The RheumNow Week in Review – 28 October 2016

Dr. Jack Cush reviews highlights, news and journal reports from this week at RheumNow.com

Simultaneous Versus Staged Bilateral Total Knee Arthroplasty

This metanalysis from 2013 reports on an important issue for orthopedists and rheumatologists alike. The issue being in those who need bilateral total knee arthroplasty, is it better to do both knees at once or to do one at a time (staged, serial) arthroplasties..

POSTURE Study: Apremilast Fails in Ankylosing Spondylitis

ClinicalTrials.gov has listed the results of the POSTURE study, a large randomized placebo-controlled trial wherein apremilast was found to yield no benefit (compared to placebo) in treating ankylosing spondylitis (AS) (32.5% vs. 36.6% ASAS20 at week 16) patients.

Kawasaki Disease Pathogenesis Hinges on Interleukin-1

Researchers from the Toronto Hospital for Sick Children have published in the Journal of Immunology that a polymorphism in the inositol-triphosphate 3-kinase C (ITPKC) (rs28493229) is associated with the pathogenesis of Kawasaki's disease (KD).

A Neural Signature in Fibromyalgia

Fibromyalgia is a well characterized condition with disordered pain processing. Although the clinical constellation and diagnostic clues are well characterized, FM lacks a diagnostic biomarker and most imaging and tissue diagnostics have been unrevealing.

Seropositivity Increases Mortality Rates in Rheumatoid Arthritis

It has been long known that rheumatoid arthritis is associated with an increased mortality rate, especially in seropositive patients and those with extraarticular manifestations.

October-September 2016 Top Social Media News

Following is a list of top tweets in September and October 2016; they were selected based on the number of clicks, retweets and likes by the viewership. More than 40,000 people were reached with the first one on our list.

ACP Guidelines on the Diagnosis and Treatment of Low Back Pain

Low back pain (LBP) is the fifth most common reason for all physician visits in the United States and nearly 25% of all U.S. adults have had LBP in the  last 3 months and nearly 6% reported at least 1 episode of severe acute low back pain in the last 1-year.

Most Clinicians Do Not Order MRI/CT for Nonspecific Low Back Pain

Low back pain (LBP) is a highly prevalent public health problem. Not surprisingly, imaging of LBP is also an expensive and often overused diagnostic tool.  

Early Intervention with Corticosteroids and IVIG is Crucial in Kawasaki Disease

The current JAMA Pediatrics issue has published a report showing that adjunctive corticosteroid therapy yielded significantly fewer coronary artery complications compared with intravenous immunoglobulin therapy alone, particularly among high-risk patients with Kawasaki disease.

×