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Power Doppler Ultrasound Detects Early Synovitis Change in APPRAISE Study

While new recommendations suggest early aggressive management of rheumatoid arthritis, our ability to assess treatment response is limited to clinical and laboratory assessment.

EU Endorses Biosimilar Etanercept (SB4) from Samsung/Biogen

Reuters today reported that a copy of the blockbuster biotech drug Enbrel (SB4) was recommended for approval in Europe on Friday, making it the second so-called biosimilar antibody medicine to win such a green light from the continent's regulators.

CMS Releases Final Rule on Joint Replacement

MedPage Today reports that the Centers for Medicare & Medicaid Services (CMS) has issued a final rule governing payment for hip and knee replacements for Medicare patients this week that includes several concessions to stakeholders, such as delaying implementation from early 2016 to later in

Opioid Use Ups the Risk of Hospitalized Infections in Rheumatoid Arthritis

Researchers from Vanderbilt University have studied the issue of opioid use in rheumatoid arthritis (RA) and whether this influences infection risk.

From Psoriasis to PsA: Who and Why?

The number of patients with psoriasis who go on to develop psoriatic arthritis (PsA) is considerably higher than has previously been estimated, a prospective cohort study found.

Psoriasis May Not Be a Risk for CV Events

Patients with psoriatic skin and joint disease are uniquely susceptible to multiple comorbidities, obesity and possibly more cardiovascular risks. In rheumatoid arthritis, the increased CV risk and CV events have been closely aligned with inflammation and disease activity.

AMA Proposes Ban on Television Drug Ads

The American Medical Association has called for a ban on direct-to-consumer (DTC) advertising for prescription drugs and medical devices, noting these forms of advertising drive up health care costs and often mislead the public.

SB4 - A Second Biosimilar Up For Review in Europe

A biosimilar of etanercept (Enbrel) made by the South Korean company Samsung Bioepis is under consideration by regulators in the European Union. Samsung Bioepis, a joint venture between Samsung Biologics and Biogen, is taking aim with its version of etanercept.

Alcohol and Methotrexate - What Do You Advise?

What are your rules on methotrexate and alcohol use? How about casual, social or occasional alcohol use? If one alcoholic beverage is ok, what about 2, 3 or six while taking MTX?

Tocilizumab & Abatacept Effective in Giant Cell Arteritis

Giant cell arteritis (GCA) is a medium and large vasculitis, wherein only glucocorticoids (GC) treatment has been the mainstay of therapy. As many will require prolonged treatment, the hazards of GC are well known, lead to substantial toxicity and morbidity.

Surviving Infection on DMARDs or Biologics

Sepsis is a dangerous and potentially fatal consequence of serious infections (SIE), particularly in susceptible populations such as the elderly and immunosuppressed. Published evidence points toward the potential role of TNF in development of sepsis.

Are Guidelines Worth the Cost?

A thoughtful perspective on the purpose, focus and cost of guideline efforts in rheumatology has been published in the journal Rheumatology.

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