MOST Study: End Stage Knee Osteoarthritis Shows Dynamic Change by MRI
Guermazi and colleagues have investigated whether end-stage knee osteoarthritis (OA), assessed as grade 4 Kellgren and Lawrence (KL) radiographic changes, are really "end stage".
News
Life Expectancy Rises, but People Living Longer with More Illness
Lancet has reported that people are living 6.2 years longer, worldside since 1990. Yet, there has been a rise in illness and disability,and a complex mix of fatal and non-fatal ailments leading to a large amount of health loss.
C5orf30 Gene is a Negative Regulator of Tissue Damage in Rheumatoid Arthritis
PNAS has reported the work of an international team of scientists from the University College Dublin and the University of Sheffield, who have studied DNA samples and biopsy samples from joints of over 1,000 rheumatoid arthritis patients in the UK and Ireland and determined the C5orf30 gene to be
DSB: Drug Shortages August 2015
RheumNow is committed to reporting safety issues in our monthly Drug Safety Bulletins. Each month we will update you with reports of new, ongoing and resolved Drug Shortages that will affect the practicing rheumatologist.
Increased Vascular Mortality in Ankylosing Spondylitis
Haroon et al has analyzed administrative claims data from Ontario, Canada and compared 21473 AS patients with 86606 normal comparators matched for age, sex, and location of residence.
Growth Hormone Protects Against Osteoporotic Fractures
This article was sourced from sciencedaily.com
In a decade-long study of the effects of growth hormone (GH), 80 women with osteoporosis on HRT, between ages of 50-70 yrs were randomized to receive GH 1.0 U or GH 2.5 U recombinant human GH or placebo sc daily during 3 years and compared to an age-matched populatoin sample of (n=120).
Hyperuricemia, Death & Kidney Disease
In a recent study published in the Journal of the American Geriatrics SocietyTaiwan investigators examined the Annual Geriatric Health Examination Program database (2006 to 2010) to estimate the all-cause, cardiovascular, and cancer mortality risks associated with serum uric acid le
Female "Viagra Pill" Controversy - Grandstanding or Equal Rights?
The FDA is under pressure over the recent approval of the "female viagra" pill. On August 18th, the FDA announced its approval for Addyi (flibanserin) to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women.
Early RA and the Chance of DMARD-Free Remission
Early and aggressive treatment of rheumatoid arthritis has become the mantra for most who manage the disease and hope to achieve optimal outcomes - including remission.
BMI at Age 20 Influences Future Risk of Low Back Pain
A nationwide, cross-sectional study of men aged 30–50 years (n=1385) examined the relationship between weight and back pain over time.
Fasenmyer Grant to Calabrese and Lederman Will Further the Interface Between Rheumatology and Virology
Two longtime collaborators studying HIV/AIDS at the Cleveland Clinic and Case Western Reserve University have received an $18.5 million grant from the Richard J. Fasenmyer Foundation.
Epidural Steroid Injections Ineffective
A meta-analysis of 30 placebo-controlled trials evaluated epidural corticosteroid injections for radiculopathy, and 8 trials were done for spinal stenosis.
