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Sodium Channels, Carbemazepine and Osteoarthritis Progression

A study published in Nature suggests that therapies affecting sodium channels could be employed to treat osteoarthritis.

SLE: A Mutated Gene and TLR7 Overexpression

EurekAlert!

A group of researchers lead by Min Ae Lee-Kirsch from the Department of Pediatrics, Medical Faculty, TUD Dresden University of Technology (Germany), studied four patients from two families who developed symptoms of SLE in the first years of life.

2023 Rheumatology Year in Review

Dr. Jack Cush reviews highlights, advances and hot topics in rheumatology from 2023 and the RheumNow website.  

2023 was a year of growth and new horizons while returning to operational and practice standards (in care and education) established before the pandemic.  

Increased CV Comorbidity in Dermatomyositis

A cohort study suggest that patients with dermatomyositis (DM) are at an increased risk for multiple comorbidities, including chronic kidney and cardiovascular disease,

Drug-Induced Dermatomyositis

A JAMA Dermatology systematic review of drug-induced dermatomyositis (DM) found the most commonly implicated agents include hydroxyurea, immune checkpoint inhibitors, statins and lipid-lowering agents, penicillamine, and tumor necrosis factor inhibitors.

2023 Rheumatology Year in Review

Here is my top 10 list (in no particular order) of 2023 advances, game-changers, and developments that changed, or will soon change, rheumatologic practices.

Hormonal Status Increases RA Risk

EurekAlert!

Early menopause—before the age of 45—taking hormone replacement therapy (HRT), and having 4 or more children are among several hormonal and reproductive factors linked to a heightened risk of rheumatoid arthritis in women, finds a large long term study published in the open access journal 

Black, Asian, and Hispanic Military Members with OA Treated Differently

MedPage Today

Black, Asian, and Hispanic members of the U.S. Armed Forces were far less likely than their white comrades to undergo knee replacement surgeries after being diagnosed with osteoarthritis (OA), military researchers found.

2023 In Memoriam

In 2023, too many of our rheumatology colleagues passed away. Here is an incomplete list of our revered fellow practitioners, mentors, role-models, and researchers.

Florida Approves Import of Drugs from Canada

Last Friday, the Food and Drug Administration (FDA) approved Florida’s plan to import certain prescription drugs directly from Canada.  Florida is the first time a state to undertake this pathway to save money.

Heritability of Osteoarthritis

A Swedish study examine the genetic contribution to various rheumatic/musculoskeletal diseases (RMDs) and showed that osteoarthritis (OA) had a large heritability compared with other RMDs.

New Year's Resolutions (1.5.2024)

Dr. Jack Cush imparts his new New Year's Resolutions for 2024 and also reviews the news and journal reports from the past week on RheumNow.com.
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