A population-based retrospective cohort study patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants demonstrated significant adverse pregnancy outcome, particularly the infants of women with SLE. This included maternal/infant rehospitalization, malformations and mortality.
The population under study was derived from the Washington State linked vital-hospital discharge records (between 1987-2014) and included women with RA (N=1,223) and SLE (N=1,354) and a comparatory group of unexposed women with singleton births.