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"It takes alot of courage to reach out and say 'I need some help on this one'" (Carla Harris) Put on your big-boy pants,

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Dr. John Cush
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"It takes alot of courage to reach out and say 'I need some help on this one'" (Carla Harris) Put on your big-boy pants, woman-up and ask for advice, not from anyone - go to the right person/people - you know who they are! https://t.co/GUs1nCvXeU

Holes in TH17 cells release IL-1α on NLRP3 activation Certain T cells can secrete cytokines that are normally part of

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Dr. John Cush
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Holes in TH17 cells release IL-1α on NLRP3 activation Certain T cells can secrete cytokines that are normally part of the innate immune system, as researchers from the Leibniz-HKI and an international research team discovered. https://t.co/lLHD66D3RP https://t.co/cym7SGD2WX

Free great handout on DRESS - Drug Reaction With Eosinophilia and Systemic Symptoms. May affect adults or children; usua

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Dr. John Cush
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Free great handout on DRESS - Drug Reaction With Eosinophilia and Systemic Symptoms. May affect adults or children; usually 2 to 8 weeks after beginning a medication. ~1 in 1000 taking specific drugs get DRESS. Allopurinol is a common cause https://t.co/X8lHtGVunC https://t.co/OjCzUXWJcz
Worse Birth Outcomes in RA and SLE

A population-based retrospective cohort study patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants demonstrated significant adverse pregnancy outcome, particularly the infants of women with SLE. This included maternal/infant rehospitalization, malformations and mortality. 

The population under study was derived from the Washington State linked vital-hospital discharge records (between 1987-2014) and included women with RA (N=1,223) and SLE (N=1,354) and a comparatory group of unexposed women with singleton births.

Bimekizumab in Active Psoriatic Arthritis - BE COMPLETE study
BE COMPLETE is published, showing that bimekizumab (BMK), a selective dual inhibitor of interleukin (IL)-17F and IL-17A, results in superior improvement in both skin and joint outcomes in psoriatic arthritis (PsA) patients who have previously failed treatment with a tumour necrosis factor-α (TNFα) inhibitor.

anti-mitochondrial antibodies (AMA) in were assayed in 404 #RA patients & found to positive in 14-26%. Importantly A

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Dr. John Cush
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anti-mitochondrial antibodies (AMA) in were assayed in 404 #RA patients & found to positive in 14-26%. Importantly AMA Abs were associated with erosive disease (p<0.05) and interstitial lung disease (p<0.01), independent of CCP or RF https://t.co/ZcrOYr0cWX https://t.co/KvZ3N5IiCB

10 best US jobs in2023, half are medical 1 Software developer 2 Nurse practioner 3 Medical/health serv manager 4 Ph

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Dr. John Cush
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10 best US jobs in2023, half are medical 1 Software developer 2 Nurse practioner 3 Medical/health serv manager 4 Physician asst 5 Information security analyst 6 Physical therapist 7 Financial manager 8 IT Manager 9 Web developer 10 Dentist https://t.co/nL5yuorzTH https://t.co/4mYspRCZX0

2022 Memorium Sadly, too many of our rheumatology colleagues passed on in 2022. Here is an (incomplete) list of notabl

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Dr. John Cush
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2022 Memorium Sadly, too many of our rheumatology colleagues passed on in 2022. Here is an (incomplete) list of notable brethren, mentors, do-gooders and great rheumatologists. https://t.co/wtr4ablgUm https://t.co/xPpgnrEQWz
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