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"FLAME" - machine learning model developed to predict SLE flares. Data from 28,433 SLE pts (2011-2022) looked at clinica

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Dr. John Cush
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"FLAME" - machine learning model developed to predict SLE flares. Data from 28,433 SLE pts (2011-2022) looked at clinical & social determinants of health (SDoH) to predict 3 mo flare risk. AUROC = 0.67; SHAP analysis identified HA, OBS, & pyuria as predictors. Is this the https://t.co/6Eqqc9w2oV

Top 20 Best Rheumatology Hospitals - 2025

U.S. News & World Report has published its Best Hospitals for 2025, listing the best among many specialties, including rheumatology.  Each year, U.S. News ranks hospitals in 15 specialties and for the 8th year in a row, Johns Hopkins Hospital in Baltimore has been named the top hospital for rheumatology by U.S. News & World Report.

PsA is worse in women--why? 100 PsA pts, serum study of differentially expressed proteins - 20 times more sex-specific

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Dr. John Cush
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PsA is worse in women--why? 100 PsA pts, serum study of differentially expressed proteins - 20 times more sex-specific DEPs in PsA males than females (PsA vs controls). In women leukotriene A-4; and in men IL-36, NEK7 & PIK3CA/PIK3R1 were significant predictors. https://t.co/JzI1n6Hf5G

CKD & Osteoporosis Rx Revisited (7.25.2025) Dr. Jack Cush reviews the news, journal and FDA updates from this past

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Dr. John Cush
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CKD & Osteoporosis Rx Revisited (7.25.2025) Dr. Jack Cush reviews the news, journal and FDA updates from this past week on RheumNow. https://t.co/k78DRpWIJS https://t.co/aYKvIhmJN1

Heart Attack No Longer the Leading Cause of Death in America . Journal of AHA reports that heart disease mortality in th

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Dr. John Cush
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Heart Attack No Longer the Leading Cause of Death in America . Journal of AHA reports that heart disease mortality in the United States dropped by 66 percent over the past five decades, driven largely by a dramatic decline in fatal heart attacks. https://t.co/whMQSMozVv https://t.co/ik6uydmspF
HCQ Preserves Renal Function in Lupus Nephritis
Lupus nephritis patients on long-term therapy with hydroxychloroquine showed significantly less decline in renal function, compared with patients treated otherwise, a 10-year retrospective study indicated.
Factors Affecting Biologic Use in Rheumatoid Arthritis

A San Francisco Rheumatoid Arthritis Panel cohort survey between 1999–2011, showed numerous sociodemographic, disease, and health characteristics that influenced the initiation of treatment with biologic agents for rheumatoid arthritis (RA).

The University of California, San Francisco Rheumatoid Arthritis Panel Study was the source of data, primarily collected by a structured annual phone survey. 

The study included 527 RA patients in 1999, and 229 persons (44%) had received biologic therapies by 2011.

Systemic immune-inflammation index (SII), as a potential biomarker -- computed as platelet count × neutrophil count/lym

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Dr. John Cush
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Systemic immune-inflammation index (SII), as a potential biomarker -- computed as platelet count × neutrophil count/lymphocyte count. SII has been shown to be useful in RA, PsA, SpA, SLE and vasculitis, reflecting disease activity, drug responses & supplements ESR & CRP levels https://t.co/LuFaYbWiWN

Review of risankizumab efficacy & safety included 545 psoriasis pts showing Mean PASI decreased from 14 to 0.5 at 20

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Dr. John Cush
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Review of risankizumab efficacy & safety included 545 psoriasis pts showing Mean PASI decreased from 14 to 0.5 at 208Wk. PASI100 achieved in 33% and 74% at 16Wk & 208Wk. Bio-naïve responded faster bio-experienced pts - only 5 pts D/C for adverse events https://t.co/VklLWpD0SF https://t.co/zZfuiFijd4

MTX or TNFi use in elderly #RA pts w/in a year of Dx of melanoma was not associated with increased mortality. This inclu

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Dr. John Cush
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MTX or TNFi use in elderly #RA pts w/in a year of Dx of melanoma was not associated with increased mortality. This included melanoma in situ (48%), localized (47%) and regional (5%) melanoma. Steroid use however was assoc w/ reduced survival. https://t.co/QOXfEf51S1 https://t.co/6BPtEV6sOU
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