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SLE Faculty Panel Q&A

SLE Faculty Panel Q&A - Featuring Drs. David Karp, Michelle Kahlenberg, and Andrea Fava; moderated by Dr. Jack Cush

Study of f 234 AAV pts. 85 (36%) developed diffuse alveolar haemorrhage. Independent predictors of DAH: 1) Age [OR=1.037); 2) PLT # [OR=0.996]; 3) ESR [OR=1.028]; 4) HgB [OR=0.978]; 5) hematuria [OR=3.77] https://t.co/eKOu5PHs4R https://t.co/mGwLAVJhAN
Dr. John Cush @RheumNow  (  View Tweet)
“50% of pts with lupus nephritis are asymptomatic . You have to have a degree of kidney damage before you have proteinuria. Proteinuria does not correlate with intrarenal activity.” – Dr. A Fava #RNL2024 @rheumnow https://t.co/UOC8MZDM8N

Dr. John Cush @RheumNow  (  View Tweet)

Danish registry study shows positive association between maternal autoimmune Dz & childhood cancer. AID assoc w/ all child CA (OR=1.25), ALL (1.52), Burkitts (2.69), CNS tumors (1.45). RA mothers AID had higher risk of all cancers (OR=2.1) https://t.co/EYHyHzOboc https://t.co/FNRrvySI8P
Dr. John Cush @RheumNow  (  View Tweet)
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Complex Autoantibody Patterns in RA

EurekAlert!

Patients with rheumatoid arthritis (RA) all have a unique and diverse set of antibodies that are involved in the development of the disease. Researchers at Utrecht University unveiled the complexity of these antibodies using powerful lab tools capable of analysing our immune system at molecular levels.

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Systemic Inflammation and Mortality in RA-ILD

Analysis of the German RABBIT registry shows that systemic inflammation, more so than disease activity, strongly influences all-cause mortality in patients with rheumatoid arthritis and prevalent interstitial lung disease (RA-ILD).

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Dr. Gabalawy: "How do you know what disease patients will develop in this preclinical autoimmunity state?" @drdavidkarp ""it's like when weeds pop up in a garden, it's random ...if ACPA Ab pops up, you might have RA, if it's dsDNA, maybe lupus."" #RNL2024 https://t.co/kDkDaDRP8X

Dr. John Cush @RheumNow  (  View Tweet)

Low urinary IL16 levels at 12 months predicts kidney survival at 3 years better than proteinuria - @Andreafava @rheumnow #RNL2024 https://t.co/4GLmJQr46C

Dr. John Cush @RheumNow  (  View Tweet)

Tuesday Night Rheumatology- Mastering SLE

Join us for session highlights from RheumNow Live 2024. This webinar will feature highlights from these lectures followed by live audience Q & A: Rethinking Pre-Clinical Disease in Lupus David Karp, MD Biology and Rx of Lupus Flares Michelle Kahlenberg, MD Current/Future Biomarkers in SLE Andrea Fava, MD

GSK May RX Update

Approaches for slowing organ damage progression in lupus

Sponsored by GSK US Medical Affairs Sponsored by GSK US Medical Affairs

Watch our videos featuring global rheumatology experts to learn about recent advances towards slowing organ damage progression in lupus. Discover how you can implement disease modification and remission treatment goals, alongside corticosteroid tapering and the earlier introduction of biologics, to help improve patient outcomes.

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Rheum Chapter Notes Dr. Jack Cush reviews this past week’s news and journal articles from https://t.co/V10S4oVFsv. https://t.co/m6pkmYeiAl https://t.co/3cr3KwV1CP
Dr. John Cush @RheumNow  (  View Tweet)
UK Early Inflammatory Arthritis Audit of 20,060 RA pts (~12k on MTX; 5K csDMARD; ~2.5K no DMARD). Serious infections (SIE) hosp rate was 3.19/100PY, death 0.1/100PY. SIE risk incr w/ age, smoking, Hi DAS28 & HAQ. 1 unit DAS28, SI risk increased by 8% https://t.co/OrNh8oYE3y https://t.co/DqbeibNMbp
Dr. John Cush @RheumNow  (  View Tweet)
Tuesday Night Rheumatology: Mastering SLE https://t.co/lhExjSsKNA

Dr. John Cush @RheumNow  (  View Tweet)

FDA issued a drug safety warning linking thiopurine (AZA, 6MP) use in pregnancy & a rare risk of intrahepatic cholestasis of pregnancy (ICP). ICP has been reported in pts w/ CD, UC, or SLE; however thiopurines are not FDA approved for these Dx https://t.co/XKoUdy4sAR https://t.co/DSU9z0v7CZ
Dr. John Cush @RheumNow  (  View Tweet)
British Society for Rheumatology (BSR) presented (at the 2024 annual BSR meeting) new guidelines for the management of Behçet's disease - how to manage skin lesions, mouth ulcers, genital ulcers, serious eye, CNS & vascular involvement https://t.co/d0bjKuubym https://t.co/lqoTeTGqZ7
Dr. John Cush @RheumNow  (  View Tweet)