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General Rheumatology

Vitamin D in Rheumatic Disease - Is It Good Enough? Vitamin D in rheumatic disease — is it sufficient? Vitamin D deficiency/insufficiency is common and linked to inflammatory rheumatic diseases, raising the question of whether low vitamin D drives immune dysregulation, disease https://t.co/Xd8s8LKqKT
Dr. John Cush @RheumNow( View Tweet )
Parvovirus B19 Infection - Images from JAMA Dermatology. 40yoM 2-days asymptomatic rash w/ fever to 39°C, w/ arthralgias, Rash on BL cheeks, inguinal, flanks, axilla. WBC =2K, CRP 1.24 mg/dl. Dx by PCR for parvovirus B19 DNA https://t.co/LGGnabvFvA https://t.co/XzPlaWkIfz
Dr. John Cush @RheumNow( View Tweet )
Lupus Mortality Risk in Young Women New research using death certificate data from 52,942 females, reveals that systemic lupus erythematosus (lupus) is a leading cause of years of potential life lost among young women in the United States, underscoring the disease’s significant https://t.co/2FSINr6gZN
Dr. John Cush @RheumNow( View Tweet )
NEJM reports a 10 yrs study of Arthroscopic Partial Meniscectomy (APM) for Degenerative Tear — randomized, sham-surgery–controlled RCT of 147 pts w/o Knee https://t.co/WMGRIOunwZ 10 years, found no signif benefit betw APM and Sham surgery (pain, function) & possible worsening https://t.co/979C7IYuyZ
Dr. John Cush @RheumNow( View Tweet )

Infectious Rheumatology (5.15.2026)

Dr. Jack Cush discusses his favorite journal articles from the past week on RheumNow.com.

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UCB has aquired Candid Therapeutics for $2 billion; plan to lead in autoimmune dz by acquiring cizutamig - a T cell engager. Its been studied in >100 pts, including early Global Phase 2 RCTs of myasthenia gravis & ILD. https://t.co/xz4uEhvxu6 https://t.co/6FS1riLecW
Dr. John Cush @RheumNow( View Tweet )
Society of Interventional Radiology position statement supports genicular artery embolization (GAE) symptomatic knee #OA pts who have failed conservative therapy and not candidates for TKA. https://t.co/fFkKqRm0s6 https://t.co/0jDhVsgyha
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JAMA Insights on Chikungunya (affects 35 million worldwide) - mosquito-borne alphavirus seen in tropics, also travelers. Dz char by fever, disabling polyarthritis; less rash, HA, myalgia, N/V, conjunctivitis; rarely myocarditis. https://t.co/Fa3cHygc4W https://t.co/jmh2WjOcI5
Dr. John Cush @RheumNow( View Tweet )
Advanced Practice Rheum: Still's Disease and Fever https://t.co/P3qbGYll8y https://t.co/6EAoVWimSI
Dr. John Cush @RheumNow( View Tweet )

Fatigue in SLE

An NIH lupus cohort study looked at fatigue in SLE and found associations with organ damage, obesity, but does not correlate with disease activity in systemic lupus erythematosus (SLE) patients.

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Another IL-17A inhibitor (Vunakizumab) for active Ankylosing Spondylitis

Vunakizumab, a novel anti–interleukin (IL) 17A monoclonal antibody, was studied in patients with active radiographic axial spondyloarthritis [r-axSpA] and found to be effective

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EGPA Review

A current review of eosinophilic granulomatosis with polyangiitis (EGPA) provides current recommendations on diagnosis and management.

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Chronic Low Back Pain Disappointments in a Randomized Trial Annals of Internal Medicine reports that patients with chronic low back pain (cLBP) may benefit from physical therapy (PT); but when that fails, other secondary measures (cognitive behavioral therapy (CBT) or https://t.co/17JObbXz5U
Dr. John Cush @RheumNow( View Tweet )
Vitamin D in Rheumatic Disease - Is It Good Enough? Vitamin D in rheumatic disease — is it sufficient? Vitamin D deficiency/insufficiency is common and linked to inflammatory rheumatic diseases, raising the question of whether low vitamin D drives immune dysregulation, disease https://t.co/CLBFii2TbR
Dr. John Cush @RheumNow( View Tweet )
🚨 SAVE THE DATE June 3–6, 2026 RheumNow is bringing you real-time coverage of #EULAR2026 👉 Breaking data 👉 Late-breakers 👉 Global expert insights Don’t miss a moment. #Rheumatology https://t.co/hqmIdeoS4H
Dr. John Cush @RheumNow( View Tweet )
APR: Still's Disease Companion slide deck for the Advanced Practice Rheum: Still's Disease and Fever video, featuring Dr. Jack Cush. https://t.co/wsUP2zEulC https://t.co/AWSNt9Uzlg
Dr. John Cush @RheumNow( View Tweet )
Influential Rheumatoid Factors (5.8.2026) Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow. https://t.co/BaugLQEIai https://t.co/WdWXAfB5lk
Dr. John Cush @RheumNow( View Tweet )

Toll-Like Receptor Drugs Effective in Cutaneous Lupus

MedPage Today

Enpatoran, an investigational oral drug that inhibits Toll-like receptors (TLR) 7 and 8, was superior to placebo in relieving lupus skin manifestations in a dose-finding phase II trial.

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Parvovirus B19 Infection - Images from JAMA Dermatology. 40yoM 2-days asymptomatic rash w/ fever to 39°C, w/ arthralgias, Rash on BL cheeks, inguinal, flanks, axilla. WBC =2K, CRP 1.24 mg/dl. Dx by PCR for parvovirus B19 DNA https://t.co/LGGnabvFvA https://t.co/yyBF9pEGls
Dr. John Cush @RheumNow( View Tweet )
Dr. Robert Terkeltaub walks through the evolution of gout at #RheumNowLive 2026. 🎧 Listen here: https://t.co/S6RXQo2Umt #Gout #Rheumatology #MedEd https://t.co/XDbTmj3MOw
Dr. John Cush @RheumNow( View Tweet )

Chronic Low Back Pain Disappointments in a Randomized Trial

Annals of Internal Medicine reports that patients with chronic low back pain (cLBP) may benefit from physical therapy (PT); but when that fails, other secondary measures (cognitive behavioral therapy (CBT) or mindfulness) may not be effective.

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Vitamin D in Rheumatic Disease - is it Good Enough?

Vitamin D deficiency or insufficiency of is highly prevalent and has been often associated with inflammatory rheumatic diseases, raising the question of whether inadequate vitamin D status contributes to immune dysregulation, incipient disease, increased disease activity, or poor skeletal
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“60-40-20” - Ed Keystone (rumor has it he was actually bidding on a copy of my textbook!)

Dr. John Cush @RheumNow( View Tweet )

In Still's disease, what is the primary life-threatening complication clinicians must monitor for? If you think you know the answer, prove it in this week's RheumIQ quiz at https://t.co/KVK8J2iaFQ https://t.co/O62ZpIciWW
Dr. John Cush @RheumNow( View Tweet )
24 systemic amyloidosis pts (AA type 46%, AL 29%); 62% joint pain & AM stiff, axial 37.5%, macroglossia (4 pts, 17%), carpal tunnel (12%), proteinuria > 1 gm 50%, CKD 21%, Cardiac amyloid 29%. Amyloid was secondary to Rheum Dx in 11/24. Better survival w/ AA than AL (91% vs https://t.co/hwkpeav4MQ
Dr. John Cush @RheumNow( View Tweet )
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