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Articles By Jack Cush, MD

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Aspergillus Arthritis - A Rare Opportunistic Infection

The International Osteoarticular Mycoses Consortitum has publist their review Aspergillus arthritis caused by invasive aspergillosis. Their review identified 31 evaluable cases, 87% of whom were males and adults.

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It's the engine that kills ya’, not the caboose

This past weekend I was fortunate to lecture at the Harvard Advances in Rheumatology Course, where I reviewed the safety issues surrounding the use of biologic therapies. In discussing infections, cancer, cardiovascular events, etc., it became very clear to me that these problems, while worrisome, are often escalated in their importance – all at the expense of what is most dangerous: RA itself.

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CPAP Use Fails to Prevent CV Events in Sleep Apnea Patients

There are numerous health hazards associated with obstructive sleep apnea (OSA), including an increased risk of cardiovascular events.

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Lupus Patients at Higher Risk for Heart Failure

Although cardiovascular disease and complications have been well-described in patients with systemic lupus erythematosus (SLE), the association between SLE and heart failure (HF) remains undefined.

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The RheumNow Week in Review – 9 September 2016

Dr. Jack Cush reviews highlights from the past week on RheumNow.com, including IBD/TNFi and cancer risk, fracture nonunion, PMR worse in women, not treating asymptomatic hyperuricemia, and shingles followed by stroke.

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P. Gingivalis Antibodies Antedate Rheumatoid Arthritis Onset

Periodontal disease, gingivitis and Porphyromonas gingivalis have been linked to the pathogenesis of rheumatoid arthritis (RA) and the production of anti-citrullinated protein antibodies (ACPA).

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Karolinska Scandal May Undermine the Nobel Prize

Nature reports that the Karolinska Institute and the affiliated Karolinska Hospital are being scrutinized for violations regarding stem cell research in patients without sufficient pre-clinical research, research ethics approval, or approval from regulatory authorities.

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Is Biologic Safety Different in the Elderly?

The factors that influence the safety of biologic therapy are numerous. Amongst them, increasing age is a potential risk factor, moreso if you also consider the polypharmacy, comorbidities and longer disease duration inherent in an elderly group of rheumatoid arthritis (RA) patients.

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AMA Policy on Freebies and Meals Clarified

A recent JAMA Internal Medicine report on pharmaceutical-sponsored meals disclosed that a $20 meal provided by a drug company could yields 2-5 times more prescriptions.  (Citation source http://buff.ly/2cd58i0)

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EMRs Causing Physician Burnout

Researchers suggest that the burden of EHRs could contribute to physician burnout. The findings of a time and motion study are published in Annals of Internal Medicine.

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