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Articles By Jack Cush, MD

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Rheumatoid Modern Management is Better but More Costly

The mantra of rheumatologists worldwide is to treat rheumatoid arthritis (RA) earlier and more aggressively. While referral of early RA patients has improved, there is little data demonstrating that more aggressive treatment works or is cost effective.

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FDA Advisory Arthritis Committee Votes to Approve the CT-P13 (infliximab) Biosimilar

On Tuesday February 9th Celltrion presented its biosimilar developmental data to the FDA as they sought approval for their CT-P13 (called Inflectra), a biosimilar of infliximab (Remicade).

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FDA Reviews Celltrion's Remicade Biosimilar Today

The arthritis advisory committee of the Food and Drug Administration (FDA) is scheduled to meet today, February 9th to review the efficacy and safety of Celltrion's biosimilar form of infliximab (Remicade) that is currently marketed in other countries.

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Parenteral Methotrexate Intolerance is High in Juvenile Idiopathic Arthritis

Juvenile idiopathic arthritis (JIA) is commonly managed with methotrexate (MTX), with many pediatric rheumatologists preferring to use parenteral MTX for compliance and absorption reasons.

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Racial Disparity in Cardiovascular Risks with Connective Tissue Disorders

Cardiovascular events account for significant morbidity and mortality in patients with rheumatoid arthritis (RA) and other connnective tissue disorders (CTD). Investigators analyzed health records from a large U.S.

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The Week in Review: 5 February 2016

Dr. Cush reviews highlights from last week's news and research in rheumatology.

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Arthritis Foundation Awards $5.5 Million to 11 Investigators

The Arthritis Foundation announced that 11 scientists were selected out of 167 proposals as the 2015 Scientific Discovery Awardees for their innovations toward finding a cure for arthritis and related diseases.

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Young Lupus Patients Have Higher Mortality Risk

A retrospective study examined mortality rates by comparing 2740 UK lupus patients  who were matched 1:4 with controls from the UK Clinical Practice Research Datalink between 1999 and 2012. (Citation source http://buff.ly/1nJWKIT)

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Should You Avoid Pneumococcal Vaccine in CAPS and Behcet's Patients

Althought EULAR currently recommends the pneumococcal vaccine be given to patients with inflammatory rheumatic diseases and the Centers for Disease Control and Prevention (CDC) recommends the vaccine in patients treated with immunosuppressive drugs, a recent brief report suggests it be

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Increased Congenital Anomalies in Children from Women with a Juvenile Arthritis History

A Quebec administrative claims analysis examined the birth outcomes of women with a history of juvenile idiopathic arthritis (JIA) who subsequently had a first-time birth (between 1983-2010).

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