Articles By Jack Cush, MD
Are Guidelines Worth the Cost?
A thoughtful perspective on the purpose, focus and cost of guideline efforts in rheumatology has been published in the journal Rheumatology.
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Pharmacy Benefit Managers at Odds with Specialty Pharmacies
Reuters and the Wall Street Journal have reported that the largest U.S. pharmacy benefit managers (PBM) of private prescription drug benefits have cut off at least eight pharmacies that work closely with drugmakers, intensifying scrutiny of a system that helps inflate drug prices.
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Hypertension Increased in Psoriasis Treated with NSAIDs, Cyclosporine or Steroids
Psoriasis and psoriatic arthritis patient have significantly higher rates of comorbidity, including hypertension (HTN). This population-based, nested case–control study analyzed an inception psoriasis cohort from Taiwan's National Health Insurance Research Database between 2000–2010.
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Biology of Bone Remodeling in Psoriatic Disease
Paine and Ritchlin have reviewed the evidence that new bone formation is centered around enthesial sites and that such findings are evident in psoriatic arthritis as well as psoriasis patients without arthritis.
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Is Baricitinib Really Better Than Adalimumab in RA: Trial Results Reviewed
Dr. Peter Taylor and colleagues presented their results of the 52-week BEAM trial wherein baricitinib (a JAK 1, 2 inhibitor) was compared to adalimumab in both clinical and radiographic outcomes. This was the most viewed abstract online at the ACR website.
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Cryoglobulinemic Vasculitis Reviewed
Cacoub et al review the common entity cryoglobulinemic vasculitis (CryoVas) in the current issue of the American Journal of Medicine. This small-vessel vasculitis involves the skin, joints, and potentially other organs, including the peripheral nervous system or the kidneys.
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Are We Using Methotrexate Appropriately?
Methotrexate is a mainstay drug in the treatment of rheumatoid arthritis (RA). Yet, we may not be using it long enough or optimizing its use.
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Concern Still Lingers for Silicone Breast Implants
What do you tell your patients who are considering augmentation mammoplasty? Or who question the safety of prior implants?
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Anifrolumab Improves Lupus Outcomes
Furie and coworkers presented the results of a 52-week phase II trial of anifrolumab (ANIFR), a type I interfernon (IFN) receptor antagonist in patients with lupus (SLE).
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Mycophenolate in Scleroderma Lung Disease
Clements et al presented the results of their Scleroderma Lung Study II wherein PSS patients with interstitial lung disease were randomized to receive either 3 grams daily of mycopheonolate or 2mg/kg/day of cyclophosphamide.
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