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Articles By Jack Cush, MD

lupus SLE

Mycophenolate in New-Onset SLE

How aggressively do you treat newly diagnosed new-onset systemic lupus erythematosus (SLE), or should you wait for organ involvement?

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TREAT EARLIER - Methotrexate in Clinically Suspect Arthralgia Patients

Lancet Rheumatology has published the results of the TREAT EARLIER trial, showing the prevention of rheumatoid arthritis may be enhanced by risk stratification, particularly in anti-citrullinated protein antibody (ACPA)-negative people with clinically suspect arthralgia.

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FOREMOST: Apremilast in Early Oligoarticular Psoriatic Arthritis

A controlled trial has shown that apremilast is effective in patients with early, oligoarticular psoriatic arthritis (PsA).

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Increased Cardiovascular Events in Lupus

A New York surveillance registry (Manhattan Lupus Surveillance Program) estimates higher rates of cardiovascular events (CVE) among systemic lupus erythematosus (SLE) patients, especially amongst younger males, Hispanic/Latinos and non-Hispanic Black patients.

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BSR Guidelines for Systemic Sclerosis Management

The British Society for Rheumatology (BSR) has updated its 2015 guidelines for the management of patients with sytemic sclerosis (SSc) based on published evidence, systematic literature review and expert opinion. 

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Different Autoantibody Phenotypes in Juvenile and Adult Myositis

A Kyoto University study compared juvenile-idiopathic inflammatory myopathy (IIM) and adult-IIM patients, demonstrating different autoantibody profiles and a more favorable outcome for n juvenile-IIM patients.

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Systemic Sclerosis Insights (9.13.2024)

Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com.

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Increasing Incidence of Morphea

A large EMR derived cohort study of over 10,000 patients with morphea (localized scleroderma) sheds light on its prevalence and associated features.

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Low Placental Transfer Rates with Risankizumab

There are significant concerns about the safety of drug use during pregnancy and lactation, especially newer biologic agents. This is complicated by a lack of research. 

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Methotrexate

Consensus Guidelines on Pediatric Methotrexate Use

Methotrexate (MTX) is commonly used in the treatment of pediatric inflammatory skin conditions, often for off-label indications. Consensus based recommendations were published to address 5 major subjects.

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